ID
40430
Beschrijving
DELCODE is conducted by DZNE, the German Center for Neurodegenerative Diseases within the Helmholtz Association. The following information was taken from https://www.dzne.de/en/research/studies/clinical-studies/delcode/. Background and aims: One of the important aims of research into Alzheimer's is to find ways of detecting the disease early – if at all possible, as soon as the first minor symptoms appear, or even before any symptoms at all have appeared. Such detection capabilities are the necessary basis for development of therapies that can be applied at such early stages in the disease. Recent research indicates that such therapies could be more effective than therapies initiated during the disease's later stages. Over a period of several years, the DELCODE study is studying persons in early stages of the disease, along with various risk groups. The research is aimed at the development of procedures for characterizing early stages of the disease, at improving prediction of the course of the disease and at identifying new markers for early diagnosis of Alzheimer's-related dementia. Overview: DELCODE is set up to run for an initial period of three years, and to include a total of 1,000 study participants, who will be examined on a yearly basis. The group of participants will include persons with no complaints (healthy control subjects), patients with slight memory impairment or mild dementia and first-degree relatives of patients with diagnosed Alzheimer's disease. The minimum age for participants is 60. Course of the study: The examinations in the framework of the study will include a comprehensive interview carried out by a study investigator, a detailed neuropsychological examination (testing of memory functions and other areas of cognitive performance), a blood test and a cranial MRI scan. Optionally, subject to the study participant's consent in each case, a lumbar puncture (collection of cerebrospinal fluid) will be carried out." For more information (e.g. principle investigator and study coordination), please visit the above link or https://www.dzne.de. This document contains the Clinical Dementia Rating (CDR) form. It has to be filled in for baseline and for all follow-ups. Due to a necessary license agreement for use of the CDR, it will only be included as subscore/result items in this version of DELCODE forms. The respective score items will have a comment in their descriptions about this to distinguish them from score items that were already defined like that by DZNE. For more information see: https://otm.wustl.edu/for-industry/tools/cdr-licensing/
Link
https://www.dzne.de/en/research/studies/clinical-studies/delcode/
Trefwoorden
Versies (1)
- 20-04-20 20-04-20 -
Houder van rechten
DZNE
Geüploaded op
20 april 2020
DOI
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Licentie
Creative Commons BY-NC 4.0
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DELCODE: DZNE – Longitudinal Cognitive Impairment and Dementia Study
Clinical Dementia Rating (CDR)
- StudyEvent: ODM
Beschrijving
Clinical Dementia Rating (CDR), modified, Informant
Alias
- UMLS CUI-1
- C0451074
- UMLS CUI-2
- C1550484
Beschrijving
CDR - memory, result
Datatype
text
Alias
- UMLS CUI [1,1]
- C3640455
- UMLS CUI [1,2]
- C1274040
Beschrijving
CDR - orientation skills, result
Datatype
text
Alias
- UMLS CUI [1,1]
- C3640456
- UMLS CUI [1,2]
- C1274040
Beschrijving
CDR - judgment and problem solving, result
Datatype
text
Alias
- UMLS CUI [1,1]
- C3640457
- UMLS CUI [1,2]
- C1274040
Beschrijving
CDR - community life, result
Datatype
text
Alias
- UMLS CUI [1,1]
- C3640458
- UMLS CUI [1,2]
- C1274040
Beschrijving
CDR - home and hobbies, result
Datatype
text
Alias
- UMLS CUI [1,1]
- C3640459
- UMLS CUI [1,2]
- C1274040
Beschrijving
CDR - personal care, result
Datatype
text
Alias
- UMLS CUI [1,1]
- C3640460
- UMLS CUI [1,2]
- C1274040
Beschrijving
Clinical Dementia Rating (CDR), modified, Subject
Alias
- UMLS CUI-1
- C0451074
- UMLS CUI-2
- C1997894
Beschrijving
Clinical Dementia Rating (CDR), modified, summary
Alias
- UMLS CUI-1
- C0451074
- UMLS CUI-2
- C0242482
Beschrijving
Clinical assessment of the severity of dementia (CDR)
Datatype
text
Alias
- UMLS CUI [1,1]
- C0451074
- UMLS CUI [1,2]
- C4534461
- UMLS CUI [1,3]
- C0392364
- UMLS CUI [1,4]
- C0497327
Beschrijving
CDR - Memory
Datatype
float
Alias
- UMLS CUI [1]
- C3640455
Beschrijving
CDR - Orientation
Datatype
float
Alias
- UMLS CUI [1]
- C3640456
Beschrijving
CDR - Judgement and problem solving
Datatype
float
Alias
- UMLS CUI [1]
- C3640457
Beschrijving
CDR - Social life
Datatype
float
Alias
- UMLS CUI [1]
- C3640458
Beschrijving
CDR - Home and hobbies
Datatype
float
Alias
- UMLS CUI [1]
- C3640459
Beschrijving
CDR - Personal care
Datatype
integer
Alias
- UMLS CUI [1]
- C3640460
Similar models
Clinical Dementia Rating (CDR)
- StudyEvent: ODM
C1550484 (UMLS CUI-2)
C1274040 (UMLS CUI [1,2])
C1274040 (UMLS CUI [1,2])
C1274040 (UMLS CUI [1,2])
C1274040 (UMLS CUI [1,2])
C1274040 (UMLS CUI [1,2])
C1274040 (UMLS CUI [1,2])
C1997894 (UMLS CUI-2)
C1274040 (UMLS CUI [1,2])
C1274040 (UMLS CUI [1,2])
C0242482 (UMLS CUI-2)
C4534461 (UMLS CUI [1,2])
C0392364 (UMLS CUI [1,3])
C0497327 (UMLS CUI [1,4])