ID
40370
Descrição
DELCODE is conducted by DZNE, the German Center for Neurodegenerative Diseases within the Helmholtz Association. The following information was taken from https://www.dzne.de/en/research/studies/clinical-studies/delcode/. Background and aims: One of the important aims of research into Alzheimer's is to find ways of detecting the disease early – if at all possible, as soon as the first minor symptoms appear, or even before any symptoms at all have appeared. Such detection capabilities are the necessary basis for development of therapies that can be applied at such early stages in the disease. Recent research indicates that such therapies could be more effective than therapies initiated during the disease's later stages. Over a period of several years, the DELCODE study is studying persons in early stages of the disease, along with various risk groups. The research is aimed at the development of procedures for characterizing early stages of the disease, at improving prediction of the course of the disease and at identifying new markers for early diagnosis of Alzheimer's-related dementia. Overview: DELCODE is set up to run for an initial period of three years, and to include a total of 1,000 study participants, who will be examined on a yearly basis. The group of participants will include persons with no complaints (healthy control subjects), patients with slight memory impairment or mild dementia and first-degree relatives of patients with diagnosed Alzheimer's disease. The minimum age for participants is 60. Course of the study: The examinations in the framework of the study will include a comprehensive interview carried out by a study investigator, a detailed neuropsychological examination (testing of memory functions and other areas of cognitive performance), a blood test and a cranial MRI scan. Optionally, subject to the study participant's consent in each case, a lumbar puncture (collection of cerebrospinal fluid) will be carried out." For more information (e.g. principle investigator and study coordination), please visit the above link or https://www.dzne.de. This document contains the Geriatric Depression Scale (GDS) and the Geriatric Anxiety Inventory – Short Form (GAI‐SF). It has to be filled in for Baseline and for all Follow-ups. For use of the questionnaire GDS no licence is required. For more information to the GDS see Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, Leirer VO. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res. 1982-83;17(1):37-49. Due to potential copyright on the questionnaire GAI-SF included in the DZNE DELCODE protocol, GAI-SF will only be included as text result item in this version of the DELCODE forms (at least until permission to publish is received from the original authors or becomes clear upon further research). The respective score items will have a comment in their descriptions about this to distinguish them from score items that were already defined like that by DZNE. For more information to GAI-SF see: Pachana, N., Byrne, G., Siddle, H., Koloski, N., Harley, E., & Arnold, E. (2007). Development and validation of the Geriatric Anxiety Inventory. International Psychogeriatrics, 19, 103-114. doi: 10.1017/S1041610206003504. Rozzini, L., Chilovi, B., Peli, M., Conti, M., Rozzini, R., Trabucchi, M., Padovani, A. (2009). Anxiety symptoms in mild cognitive impairment. International Journal of Geriatric Psychiatry, 24, 300-305. doi: 10.1002/gps.2106.
Link
https://www.dzne.de/en/research/studies/clinical-studies/delcode/
Palavras-chave
Versões (1)
- 14/04/2020 14/04/2020 -
Titular dos direitos
DZNE
Transferido a
14 de abril de 2020
DOI
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Licença
Creative Commons BY-NC 4.0
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DELCODE: DZNE – Longitudinal Cognitive Impairment and Dementia Study
Geriatric Depression Scale (GDS), Geriatric Anxiety Inventory – Short Form (GAI‐SF) (Geriatrische Depressionsskala (GDS) und GAI-SF)
Descrição
Geriatrische Depressionsskala (GDS)
Alias
- UMLS CUI-1
- C0451184
Descrição
GDS, time period
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C1948053
Descrição
GDS, satisfaction with life
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C0392352
Descrição
GDS, quit activities and interests
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C0543488
- UMLS CUI [1,3]
- C1272694
- UMLS CUI [2,1]
- C0451184
- UMLS CUI [2,2]
- C0034872
- UMLS CUI [2,3]
- C1272694
Descrição
GDS, empty Life
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C4062183
Descrição
GDS, often boredom
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C0332183
- UMLS CUI [1,3]
- C0006019
Descrição
GDS, usually cheerful mood
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C3888388
- UMLS CUI [1,3]
- C0018592
Descrição
GDS, afraid that something bad is going to happen to you
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C1288289
- UMLS CUI [1,3]
- C1954037
Descrição
GDS, usually happiness
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C3888388
- UMLS CUI [1,3]
- C0018592
Descrição
GDS, often helplessness
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C0332183
- UMLS CUI [1,3]
- C2987395
Descrição
GDS, prefer staying at home than enterprise new
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C0558295
- UMLS CUI [1,3]
- C0442519
- UMLS CUI [2,1]
- C0451184
- UMLS CUI [2,2]
- C1298908
- UMLS CUI [2,3]
- C0558295
- UMLS CUI [2,4]
- C0596545
- UMLS CUI [2,5]
- C0205314
- UMLS CUI [2,6]
- C0034872
Descrição
GDS, subjectively more problems with memory than others
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C0439655
- UMLS CUI [1,3]
- C0233794
- UMLS CUI [1,4]
- C0439093
- UMLS CUI [1,5]
- C0205394
Descrição
GDS, worthiness of life
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C3261639
Descrição
GDS, self-worth
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C1821293
Descrição
GDS, power
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C3842459
Descrição
GDS, judgement of general situation
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C0150041
Descrição
GDS, comparison to others
Tipo de dados
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C1707455
- UMLS CUI [1,3]
- C0205394
- UMLS CUI [1,4]
- C2987225
Descrição
Total GDS
Tipo de dados
integer
Alias
- UMLS CUI [1]
- C1954099
Descrição
Geriatric Anxiety Inventory – Short Form (GAI‐SF)
Alias
- UMLS CUI-1
- C1704440
- UMLS CUI-2
- C0003467
- UMLS CUI-3
- C0034394
- UMLS CUI-4
- C1806781
Descrição
Da für die Nutzung des GAI-SF eine LIzenz erforderlich ist, sind die ursprünglichen 5 Fragen in dieser Version der DELCODE Form nur als gemeinsames Ergebnisitem umgesetzt.
Tipo de dados
text
Alias
- UMLS CUI [1,1]
- C1704440
- UMLS CUI [1,2]
- C0003467
- UMLS CUI [1,3]
- C0034394
- UMLS CUI [1,4]
- C1806781
Similar models
Geriatric Depression Scale (GDS), Geriatric Anxiety Inventory – Short Form (GAI‐SF) (Geriatrische Depressionsskala (GDS) und GAI-SF)
C1948053 (UMLS CUI [1,2])
C0392352 (UMLS CUI [1,2])
C0543488 (UMLS CUI [1,2])
C1272694 (UMLS CUI [1,3])
C0451184 (UMLS CUI [2,1])
C0034872 (UMLS CUI [2,2])
C1272694 (UMLS CUI [2,3])
C4062183 (UMLS CUI [1,2])
C0332183 (UMLS CUI [1,2])
C0006019 (UMLS CUI [1,3])
C3888388 (UMLS CUI [1,2])
C0018592 (UMLS CUI [1,3])
C1288289 (UMLS CUI [1,2])
C1954037 (UMLS CUI [1,3])
C3888388 (UMLS CUI [1,2])
C0018592 (UMLS CUI [1,3])
C0332183 (UMLS CUI [1,2])
C2987395 (UMLS CUI [1,3])
C0558295 (UMLS CUI [1,2])
C0442519 (UMLS CUI [1,3])
C0451184 (UMLS CUI [2,1])
C1298908 (UMLS CUI [2,2])
C0558295 (UMLS CUI [2,3])
C0596545 (UMLS CUI [2,4])
C0205314 (UMLS CUI [2,5])
C0034872 (UMLS CUI [2,6])
C0439655 (UMLS CUI [1,2])
C0233794 (UMLS CUI [1,3])
C0439093 (UMLS CUI [1,4])
C0205394 (UMLS CUI [1,5])
C3261639 (UMLS CUI [1,2])
C1821293 (UMLS CUI [1,2])
C3842459 (UMLS CUI [1,2])
C0150041 (UMLS CUI [1,2])
C1707455 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C2987225 (UMLS CUI [1,4])
C0003467 (UMLS CUI-2)
C0034394 (UMLS CUI-3)
C1806781 (UMLS CUI-4)
C0003467 (UMLS CUI [1,2])
C0034394 (UMLS CUI [1,3])
C1806781 (UMLS CUI [1,4])