ID
40370
Descrizione
DELCODE is conducted by DZNE, the German Center for Neurodegenerative Diseases within the Helmholtz Association. The following information was taken from https://www.dzne.de/en/research/studies/clinical-studies/delcode/. Background and aims: One of the important aims of research into Alzheimer's is to find ways of detecting the disease early – if at all possible, as soon as the first minor symptoms appear, or even before any symptoms at all have appeared. Such detection capabilities are the necessary basis for development of therapies that can be applied at such early stages in the disease. Recent research indicates that such therapies could be more effective than therapies initiated during the disease's later stages. Over a period of several years, the DELCODE study is studying persons in early stages of the disease, along with various risk groups. The research is aimed at the development of procedures for characterizing early stages of the disease, at improving prediction of the course of the disease and at identifying new markers for early diagnosis of Alzheimer's-related dementia. Overview: DELCODE is set up to run for an initial period of three years, and to include a total of 1,000 study participants, who will be examined on a yearly basis. The group of participants will include persons with no complaints (healthy control subjects), patients with slight memory impairment or mild dementia and first-degree relatives of patients with diagnosed Alzheimer's disease. The minimum age for participants is 60. Course of the study: The examinations in the framework of the study will include a comprehensive interview carried out by a study investigator, a detailed neuropsychological examination (testing of memory functions and other areas of cognitive performance), a blood test and a cranial MRI scan. Optionally, subject to the study participant's consent in each case, a lumbar puncture (collection of cerebrospinal fluid) will be carried out." For more information (e.g. principle investigator and study coordination), please visit the above link or https://www.dzne.de. This document contains the Geriatric Depression Scale (GDS) and the Geriatric Anxiety Inventory – Short Form (GAI‐SF). It has to be filled in for Baseline and for all Follow-ups. For use of the questionnaire GDS no licence is required. For more information to the GDS see Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, Leirer VO. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res. 1982-83;17(1):37-49. Due to potential copyright on the questionnaire GAI-SF included in the DZNE DELCODE protocol, GAI-SF will only be included as text result item in this version of the DELCODE forms (at least until permission to publish is received from the original authors or becomes clear upon further research). The respective score items will have a comment in their descriptions about this to distinguish them from score items that were already defined like that by DZNE. For more information to GAI-SF see: Pachana, N., Byrne, G., Siddle, H., Koloski, N., Harley, E., & Arnold, E. (2007). Development and validation of the Geriatric Anxiety Inventory. International Psychogeriatrics, 19, 103-114. doi: 10.1017/S1041610206003504. Rozzini, L., Chilovi, B., Peli, M., Conti, M., Rozzini, R., Trabucchi, M., Padovani, A. (2009). Anxiety symptoms in mild cognitive impairment. International Journal of Geriatric Psychiatry, 24, 300-305. doi: 10.1002/gps.2106.
collegamento
https://www.dzne.de/en/research/studies/clinical-studies/delcode/
Keywords
versioni (1)
- 14/04/20 14/04/20 -
Titolare del copyright
DZNE
Caricato su
14 aprile 2020
DOI
Per favore, per richiedere un accesso.
Licenza
Creative Commons BY-NC 4.0
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DELCODE: DZNE – Longitudinal Cognitive Impairment and Dementia Study
Geriatric Depression Scale (GDS), Geriatric Anxiety Inventory – Short Form (GAI‐SF) (Geriatrische Depressionsskala (GDS) und GAI-SF)
Descrizione
Geriatrische Depressionsskala (GDS)
Alias
- UMLS CUI-1
- C0451184
Descrizione
GDS, time period
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C1948053
Descrizione
GDS, satisfaction with life
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C0392352
Descrizione
GDS, quit activities and interests
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C0543488
- UMLS CUI [1,3]
- C1272694
- UMLS CUI [2,1]
- C0451184
- UMLS CUI [2,2]
- C0034872
- UMLS CUI [2,3]
- C1272694
Descrizione
GDS, empty Life
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C4062183
Descrizione
GDS, often boredom
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C0332183
- UMLS CUI [1,3]
- C0006019
Descrizione
GDS, usually cheerful mood
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C3888388
- UMLS CUI [1,3]
- C0018592
Descrizione
GDS, afraid that something bad is going to happen to you
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C1288289
- UMLS CUI [1,3]
- C1954037
Descrizione
GDS, usually happiness
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C3888388
- UMLS CUI [1,3]
- C0018592
Descrizione
GDS, often helplessness
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C0332183
- UMLS CUI [1,3]
- C2987395
Descrizione
GDS, prefer staying at home than enterprise new
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C0558295
- UMLS CUI [1,3]
- C0442519
- UMLS CUI [2,1]
- C0451184
- UMLS CUI [2,2]
- C1298908
- UMLS CUI [2,3]
- C0558295
- UMLS CUI [2,4]
- C0596545
- UMLS CUI [2,5]
- C0205314
- UMLS CUI [2,6]
- C0034872
Descrizione
GDS, subjectively more problems with memory than others
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C0439655
- UMLS CUI [1,3]
- C0233794
- UMLS CUI [1,4]
- C0439093
- UMLS CUI [1,5]
- C0205394
Descrizione
GDS, worthiness of life
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C3261639
Descrizione
GDS, self-worth
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C1821293
Descrizione
GDS, power
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C3842459
Descrizione
GDS, judgement of general situation
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C0150041
Descrizione
GDS, comparison to others
Tipo di dati
integer
Alias
- UMLS CUI [1,1]
- C0451184
- UMLS CUI [1,2]
- C1707455
- UMLS CUI [1,3]
- C0205394
- UMLS CUI [1,4]
- C2987225
Descrizione
Total GDS
Tipo di dati
integer
Alias
- UMLS CUI [1]
- C1954099
Descrizione
Geriatric Anxiety Inventory – Short Form (GAI‐SF)
Alias
- UMLS CUI-1
- C1704440
- UMLS CUI-2
- C0003467
- UMLS CUI-3
- C0034394
- UMLS CUI-4
- C1806781
Descrizione
Da für die Nutzung des GAI-SF eine LIzenz erforderlich ist, sind die ursprünglichen 5 Fragen in dieser Version der DELCODE Form nur als gemeinsames Ergebnisitem umgesetzt.
Tipo di dati
text
Alias
- UMLS CUI [1,1]
- C1704440
- UMLS CUI [1,2]
- C0003467
- UMLS CUI [1,3]
- C0034394
- UMLS CUI [1,4]
- C1806781
Similar models
Geriatric Depression Scale (GDS), Geriatric Anxiety Inventory – Short Form (GAI‐SF) (Geriatrische Depressionsskala (GDS) und GAI-SF)
C1948053 (UMLS CUI [1,2])
C0392352 (UMLS CUI [1,2])
C0543488 (UMLS CUI [1,2])
C1272694 (UMLS CUI [1,3])
C0451184 (UMLS CUI [2,1])
C0034872 (UMLS CUI [2,2])
C1272694 (UMLS CUI [2,3])
C4062183 (UMLS CUI [1,2])
C0332183 (UMLS CUI [1,2])
C0006019 (UMLS CUI [1,3])
C3888388 (UMLS CUI [1,2])
C0018592 (UMLS CUI [1,3])
C1288289 (UMLS CUI [1,2])
C1954037 (UMLS CUI [1,3])
C3888388 (UMLS CUI [1,2])
C0018592 (UMLS CUI [1,3])
C0332183 (UMLS CUI [1,2])
C2987395 (UMLS CUI [1,3])
C0558295 (UMLS CUI [1,2])
C0442519 (UMLS CUI [1,3])
C0451184 (UMLS CUI [2,1])
C1298908 (UMLS CUI [2,2])
C0558295 (UMLS CUI [2,3])
C0596545 (UMLS CUI [2,4])
C0205314 (UMLS CUI [2,5])
C0034872 (UMLS CUI [2,6])
C0439655 (UMLS CUI [1,2])
C0233794 (UMLS CUI [1,3])
C0439093 (UMLS CUI [1,4])
C0205394 (UMLS CUI [1,5])
C3261639 (UMLS CUI [1,2])
C1821293 (UMLS CUI [1,2])
C3842459 (UMLS CUI [1,2])
C0150041 (UMLS CUI [1,2])
C1707455 (UMLS CUI [1,2])
C0205394 (UMLS CUI [1,3])
C2987225 (UMLS CUI [1,4])
C0003467 (UMLS CUI-2)
C0034394 (UMLS CUI-3)
C1806781 (UMLS CUI-4)
C0003467 (UMLS CUI [1,2])
C0034394 (UMLS CUI [1,3])
C1806781 (UMLS CUI [1,4])