ID

39943

Description

https://www.hl7.org/fhir/resourcelist.html (accessed at 14.02.2020) This form contains an incomplete implementation of the FHIR Resource SubstanceProtein (0). After preliminary review, it contains the data elements that request clinical information.

Link

https://www.hl7.org/fhir/resourcelist.html

Keywords

Versions (4)
  1. 2/24/20 2/24/20 -
  2. 3/5/20 3/5/20 -
  3. 3/5/20 3/5/20 -
  4. 3/18/20 3/18/20 -
Copyright Holder

HL7 FHIR

Uploaded on

March 5, 2020

DOI

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License

Creative Commons BY-NC 4.0
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FHIR v4.0.1

English

Resource SubstanceProtein (0)

1 forms  
SubstanceProtein (0)
Description

SubstanceProtein (0)

Alias
UMLS CUI-1
C0439861
UMLS CUI-2
C0033684
SubstanceProtein.sequenceType
Description

The SubstanceProtein descriptive elements will only be used when a complete or partial amino acid sequence is available or derivable from a nucleic acid sequence.

Data type

text

Alias
UMLS CUI [1,1]
C0033684
UMLS CUI [1,2]
C0002518
UMLS CUI [1,3]
C0332307
SubstanceProtein.numberOfSubunits
Description

Number of linear sequences of amino acids linked through peptide bonds. The number of subunits constituting the SubstanceProtein shall be described. It is possible that the number of subunits can be variable.

Data type

integer

Alias
UMLS CUI [1,1]
C0033684
UMLS CUI [1,2]
C0002520
UMLS CUI [1,3]
C1711351
UMLS CUI [1,4]
C0449788
SubstanceProtein.disulfideLinkage
Description

The disulphide bond between two cysteine residues either on the same subunit or on two different subunits shall be described. The position of the disulfide bonds in the SubstanceProtein shall be listed in increasing order of subunit number and position within subunit followed by the abbreviation of the amino acids involved. The disulfide linkage positions shall actually contain the amino acid Cysteine at the respective positions.

Data type

text

Alias
UMLS CUI [1,1]
C1511997
UMLS CUI [1,2]
C0002520
UMLS CUI [1,3]
C0033684
SubstanceProtein.subunit.subunit
Description

Index of primary sequences of amino acids linked through peptide bonds in order of decreasing length. Sequences of the same length will be ordered by molecular weight. Subunits that have identical sequences will be repeated and have sequential subscripts.

Data type

text

Alias
UMLS CUI [1,1]
C0033684
UMLS CUI [1,2]
C1711351
UMLS CUI [1,3]
C0918012
UMLS CUI [1,4]
C1519249
UMLS CUI [1,5]
C0002520
UMLS CUI [1,6]
C0678595
UMLS CUI [1,7]
C0442797
UMLS CUI [1,8]
C1444754
SubstanceProtein.subunit.sequence
Description

The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single-letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence.

Data type

text

Alias
UMLS CUI [1,1]
C0033684
UMLS CUI [1,2]
C1711351
UMLS CUI [1,3]
C1519249
UMLS CUI [1,4]
C0002520
SubstanceProtein.subunit.length
Description

SubstanceProtein.subunit.length

Data type

integer

Alias
UMLS CUI [1,1]
C0033684
UMLS CUI [1,2]
C0002520
UMLS CUI [1,3]
C1711351
UMLS CUI [1,4]
C1444754
SubstanceProtein.subunit.sequenceAttachment
Description

The sequence information shall be provided enumerating the amino acids from N- to C-terminal end using standard single-letter amino acid codes. Uppercase shall be used for L-amino acids and lowercase for D-amino acids. Transcribed SubstanceProteins will always be described using the translated sequence; for synthetic peptide containing amino acids that are not represented with a single letter code an X should be used within the sequence. The modified amino acids will be distinguished by their position in the sequence.

Data type

text

Alias
UMLS CUI [1,1]
C0033684
UMLS CUI [1,2]
C0002518
UMLS CUI [1,3]
C1711351
UMLS CUI [1,4]
C1999228
SubstanceProtein.subunit.cTerminalModification
Description

SubstanceProtein.subunit.cTerminalModification

Data type

text

Alias
UMLS CUI [1,1]
C0033684
UMLS CUI [1,2]
C0002520
UMLS CUI [1,3]
C1711351
UMLS CUI [1,4]
C3158165
SubstanceProtein.subunit.nTerminalModification
Description

SubstanceProtein.subunit.nTerminalModification

Data type

text

Alias
UMLS CUI [1,1]
C0033684
UMLS CUI [1,2]
C0002520
UMLS CUI [1,3]
C1711351
UMLS CUI [1,4]
C1623126
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Similar models

Resource SubstanceProtein (0)

1 forms
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
SubstanceProtein (0)
C0439861 (UMLS CUI-1)
C0033684 (UMLS CUI-2)
SubstanceProtein.sequenceType
Item
SubstanceProtein.sequenceType
text
C0033684 (UMLS CUI [1,1])
C0002518 (UMLS CUI [1,2])
C0332307 (UMLS CUI [1,3])
SubstanceProtein.numberOfSubunits
Item
SubstanceProtein.numberOfSubunits
integer
C0033684 (UMLS CUI [1,1])
C0002520 (UMLS CUI [1,2])
C1711351 (UMLS CUI [1,3])
C0449788 (UMLS CUI [1,4])
SubstanceProtein.disulfideLinkage
Item
SubstanceProtein.disulfideLinkage
text
C1511997 (UMLS CUI [1,1])
C0002520 (UMLS CUI [1,2])
C0033684 (UMLS CUI [1,3])
SubstanceProtein.subunit.subunit
Item
SubstanceProtein.subunit.subunit
text
C0033684 (UMLS CUI [1,1])
C1711351 (UMLS CUI [1,2])
C0918012 (UMLS CUI [1,3])
C1519249 (UMLS CUI [1,4])
C0002520 (UMLS CUI [1,5])
C0678595 (UMLS CUI [1,6])
C0442797 (UMLS CUI [1,7])
C1444754 (UMLS CUI [1,8])
SubstanceProtein.subunit.sequence
Item
SubstanceProtein.subunit.sequence
text
C0033684 (UMLS CUI [1,1])
C1711351 (UMLS CUI [1,2])
C1519249 (UMLS CUI [1,3])
C0002520 (UMLS CUI [1,4])
SubstanceProtein.subunit.length
Item
SubstanceProtein.subunit.length
integer
C0033684 (UMLS CUI [1,1])
C0002520 (UMLS CUI [1,2])
C1711351 (UMLS CUI [1,3])
C1444754 (UMLS CUI [1,4])
SubstanceProtein.subunit.sequenceAttachment
Item
SubstanceProtein.subunit.sequenceAttachment
text
C0033684 (UMLS CUI [1,1])
C0002518 (UMLS CUI [1,2])
C1711351 (UMLS CUI [1,3])
C1999228 (UMLS CUI [1,4])
SubstanceProtein.subunit.cTerminalModification
Item
SubstanceProtein.subunit.cTerminalModification
text
C0033684 (UMLS CUI [1,1])
C0002520 (UMLS CUI [1,2])
C1711351 (UMLS CUI [1,3])
C3158165 (UMLS CUI [1,4])
SubstanceProtein.subunit.nTerminalModification
Item
SubstanceProtein.subunit.nTerminalModification
text
C0033684 (UMLS CUI [1,1])
C0002520 (UMLS CUI [1,2])
C1711351 (UMLS CUI [1,3])
C1623126 (UMLS CUI [1,4])
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