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ID

38817

Beschreibung

Study ID: 111610 Clinical Study ID: 111610 Study Title: A randomised, double-blind, placebo-controlled study in healthy volunteers to examine the safety, tolerability and pharmacokinetics of a) single, ascending and b) twice-daily repeat doses of intranasal SB-705498. Patient Level Data: Study Listed on ClinicalStudyDataRequest.com Clinicaltrials.gov Identifier: NCT00907933 Sponsor: GlaxoSmithKline Phase: Phase 1 Study Recruitment Status: Completed Generic Name: SB705498, Placebo Study Indication: Rhinitis

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  1. 06.11.19 06.11.19 -
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GlaxoSmithKline

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6. November 2019

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    Safety, tolerability and pharmacokinetics of single, ascending and twice-daily repeat doses of intranasal SB-705498 NCT00907933

    Visual Analogue Scale (Period 1 - 5; Day 1 - Day 16)

    Visual Analogue Scale - Dosing Date and Time (Period 1 - 5)
    Beschreibung

    Visual Analogue Scale - Dosing Date and Time (Period 1 - 5)

    Alias
    UMLS CUI-1
    C2959685
    UMLS CUI-2
    C0178602
    UMLS CUI-3
    C1264639
    AM Dosing date/ time
    Beschreibung

    AM Dosing date/ time

    Datentyp

    datetime

    Alias
    UMLS CUI [1,1]
    C0178602
    UMLS CUI [1,2]
    C1264639
    UMLS CUI [1,3]
    C4331833
    PM Dosing date/ time
    Beschreibung

    PM Dosing date/ time

    Datentyp

    datetime

    Alias
    UMLS CUI [1,1]
    C0178602
    UMLS CUI [1,2]
    C1264639
    UMLS CUI [1,3]
    C1509133
    Visual Analogue Scale (Period 1 - 5)
    Beschreibung

    Visual Analogue Scale (Period 1 - 5)

    Alias
    UMLS CUI-1
    C2959685
    Timepoint
    Beschreibung

    Timepoint

    Datentyp

    integer

    Alias
    UMLS CUI [1]
    C2348792
    Please check if not done
    Beschreibung

    Please check if not done

    Datentyp

    text

    Alias
    UMLS CUI [1]
    C1272696
    Date/ Time of assessment
    Beschreibung

    Date/ Time of assessment

    Datentyp

    datetime

    Alias
    UMLS CUI [1,1]
    C2985720
    UMLS CUI [1,2]
    C1264639
    Nose not runny/Nose extremely runny
    Beschreibung

    Nose not runny/Nose extremely runny

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C1260880
    mm
    Nose clear/Nose completely blocked
    Beschreibung

    Nose clear/Nose completely blocked

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0027424
    mm
    Nose not itchy/Nose extremely itchy
    Beschreibung

    Nose not itchy/Nose extremely itchy

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0850060
    mm
    Nose not sore/Nose as sore as it has ever been
    Beschreibung

    Nose not sore/Nose as sore as it has ever been

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0857495
    mm
    Nose not dry/Nose as dry as it has ever been
    Beschreibung

    Nose not dry/Nose as dry as it has ever been

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0231919
    mm
    Throat not sore/Throat as sore as it has ever been
    Beschreibung

    Throat not sore/Throat as sore as it has ever been

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0242429
    mm
    Sense of taste normal/ Sense of taste completely abnormal
    Beschreibung

    Sense of taste normal/ Sense of taste completely abnormal

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0039336
    mm
    Taste nothing/Taste something very strongly
    Beschreibung

    Taste nothing/Taste something very strongly

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C1301555
    mm
    Sense of smell normal/ Sense of smell completely abnormal
    Beschreibung

    Sense of smell normal/ Sense of smell completely abnormal

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0037361
    mm
    Smell nothing/Smell something very strongly
    Beschreibung

    Smell nothing/Smell something very strongly

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C2712084
    mm
    Nasal symptom: (No symptoms/Worst symptoms I have ever had)
    Beschreibung

    Nasal symptom: (No symptoms/Worst symptoms I have ever had)

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0231918
    mm
    Nasal symptom: (No symptoms/Worst symptoms I have ever had)
    Beschreibung

    Nasal symptom: (No symptoms/Worst symptoms I have ever had)

    Datentyp

    text

    Alias
    UMLS CUI [1]
    C0231918
    Specify symptom
    Beschreibung

    Specify symptom

    Datentyp

    text

    Alias
    UMLS CUI [1,1]
    C1457887
    UMLS CUI [1,2]
    C2348235
    Visual Analogue Scale (Day 3 - Day 13)
    Beschreibung

    Visual Analogue Scale (Day 3 - Day 13)

    Alias
    UMLS CUI-1
    C2959685
    Day of assessment
    Beschreibung

    Day of assessment

    Datentyp

    integer

    Alias
    UMLS CUI [1]
    C2985720
    AM Dosing date/ time
    Beschreibung

    AM Dosing date/ time

    Datentyp

    datetime

    Alias
    UMLS CUI [1,1]
    C0178602
    UMLS CUI [1,2]
    C1264639
    UMLS CUI [1,3]
    C4331833
    PM Dosing date/ time
    Beschreibung

    PM Dosing date/ time

    Datentyp

    datetime

    Alias
    UMLS CUI [1,1]
    C0178602
    UMLS CUI [1,2]
    C1264639
    UMLS CUI [1,3]
    C1509133
    Timepoint
    Beschreibung

    Timepoint

    Datentyp

    integer

    Alias
    UMLS CUI [1]
    C2348792
    Date/ Time of assessment
    Beschreibung

    Date/ Time of assessment

    Datentyp

    datetime

    Alias
    UMLS CUI [1,1]
    C2985720
    UMLS CUI [1,2]
    C1264639
    Nose not runny/Nose extremely runny
    Beschreibung

    Nose not runny/Nose extremely runny

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C1260880
    mm
    Nose clear/Nose completely blocked
    Beschreibung

    Nose clear/Nose completely blocked

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0027424
    mm
    Nose not itchy/Nose extremely itchy
    Beschreibung

    Nose not itchy/Nose extremely itchy

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0850060
    mm
    Nose not sore/Nose as sore as it has ever been
    Beschreibung

    Nose not sore/Nose as sore as it has ever been

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0857495
    mm
    Nose not dry/Nose as dry as it has ever been
    Beschreibung

    Nose not dry/Nose as dry as it has ever been

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0231919
    mm
    Throat not sore/Throat as sore as it has ever been
    Beschreibung

    Throat not sore/Throat as sore as it has ever been

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0242429
    mm
    Sense of taste normal/ Sense of taste completely abnormal
    Beschreibung

    Sense of taste normal/ Sense of taste completely abnormal

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0039336
    mm
    Taste nothing/Taste something very strongly
    Beschreibung

    Taste nothing/Taste something very strongly

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C1301555
    mm
    Sense of smell normal/ Sense of smell completely abnormal
    Beschreibung

    Sense of smell normal/ Sense of smell completely abnormal

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0037361
    mm
    Smell nothing/Smell something very strongly
    Beschreibung

    Smell nothing/Smell something very strongly

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C2712084
    mm
    Nasal symptom: (No symptoms/Worst symptoms I have ever had)
    Beschreibung

    Nasal symptom: (No symptoms/Worst symptoms I have ever had)

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0231918
    mm
    Nasal symptom: (No symptoms/Worst symptoms I have ever had)
    Beschreibung

    Nasal symptom: (No symptoms/Worst symptoms I have ever had)

    Datentyp

    text

    Alias
    UMLS CUI [1]
    C0231918
    Specify symptom
    Beschreibung

    Specify symptom

    Datentyp

    text

    Alias
    UMLS CUI [1,1]
    C1457887
    UMLS CUI [1,2]
    C2348235
    Visual Analogue Scale - Dosing date/ time (Day 14 - 16)
    Beschreibung

    Visual Analogue Scale - Dosing date/ time (Day 14 - 16)

    Alias
    UMLS CUI-1
    C2959685
    UMLS CUI-2
    C0178602
    UMLS CUI-3
    C1264639
    AM Dosing date/ time
    Beschreibung

    AM Dosing date/ time

    Datentyp

    datetime

    Alias
    UMLS CUI [1,1]
    C0178602
    UMLS CUI [1,2]
    C1264639
    UMLS CUI [1,3]
    C4331833
    PM Dosing date/ time
    Beschreibung

    PM Dosing date/ time

    Datentyp

    datetime

    Alias
    UMLS CUI [1,1]
    C0178602
    UMLS CUI [1,2]
    C1264639
    UMLS CUI [1,3]
    C1509133
    Visual Analogue Scale (Day 14 - 16)
    Beschreibung

    Visual Analogue Scale (Day 14 - 16)

    Alias
    UMLS CUI-1
    C2959685
    Timepoint
    Beschreibung

    Timepoint

    Datentyp

    integer

    Alias
    UMLS CUI [1]
    C2348792
    Date/ Time of assessment
    Beschreibung

    Date/ Time of assessment

    Datentyp

    datetime

    Alias
    UMLS CUI [1,1]
    C2985720
    UMLS CUI [1,2]
    C1264639
    Nose not runny/Nose extremely runny
    Beschreibung

    Nose not runny/Nose extremely runny

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C1260880
    mm
    Nose clear/Nose completely blocked
    Beschreibung

    Nose clear/Nose completely blocked

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0027424
    mm
    Nose not itchy/Nose extremely itchy
    Beschreibung

    Nose not itchy/Nose extremely itchy

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0850060
    mm
    Nose not sore/Nose as sore as it has ever been
    Beschreibung

    Nose not sore/Nose as sore as it has ever been

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0857495
    mm
    Nose not dry/Nose as dry as it has ever been
    Beschreibung

    Nose not dry/Nose as dry as it has ever been

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0231919
    mm
    Throat not sore/Throat as sore as it has ever been
    Beschreibung

    Throat not sore/Throat as sore as it has ever been

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0242429
    mm
    Sense of taste normal/ Sense of taste completely abnormal
    Beschreibung

    Sense of taste normal/ Sense of taste completely abnormal

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0039336
    mm
    Taste nothing/Taste something very strongly
    Beschreibung

    Taste nothing/Taste something very strongly

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C1301555
    mm
    Sense of smell normal/ Sense of smell completely abnormal
    Beschreibung

    Sense of smell normal/ Sense of smell completely abnormal

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0037361
    mm
    Smell nothing/Smell something very strongly
    Beschreibung

    Smell nothing/Smell something very strongly

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C2712084
    mm
    Nasal symptom: (No symptoms/Worst symptoms I have ever had)
    Beschreibung

    Nasal symptom: (No symptoms/Worst symptoms I have ever had)

    Datentyp

    integer

    Maßeinheiten
    • mm
    Alias
    UMLS CUI [1]
    C0231918
    mm
    Nasal symptom: (No symptoms/Worst symptoms I have ever had)
    Beschreibung

    Nasal symptom: (No symptoms/Worst symptoms I have ever had)

    Datentyp

    text

    Alias
    UMLS CUI [1]
    C0231918
    Specify symptom
    Beschreibung

    Specify symptom

    Datentyp

    text

    Alias
    UMLS CUI [1,1]
    C1457887
    UMLS CUI [1,2]
    C2348235

    Ähnliche Modelle

    Visual Analogue Scale (Period 1 - 5; Day 1 - Day 16)

    Name
    Typ
    Description | Question | Decode (Coded Value)
    Datentyp
    Alias
    Item Group
    Visual Analogue Scale - Dosing Date and Time (Period 1 - 5)
    C2959685 (UMLS CUI-1)
    C0178602 (UMLS CUI-2)
    C1264639 (UMLS CUI-3)
    AM Dosing date/ time
    Item
    AM Dosing date/ time
    datetime
    C0178602 (UMLS CUI [1,1])
    C1264639 (UMLS CUI [1,2])
    C4331833 (UMLS CUI [1,3])
    PM Dosing date/ time
    Item
    PM Dosing date/ time
    datetime
    C0178602 (UMLS CUI [1,1])
    C1264639 (UMLS CUI [1,2])
    C1509133 (UMLS CUI [1,3])
    Item Group
    Visual Analogue Scale (Period 1 - 5)
    C2959685 (UMLS CUI-1)
    Item
    Timepoint
    integer
    C2348792 (UMLS CUI [1])
    Code List
    Timepoint
    CL Item
    Pre dose (1)
    CL Item
    15 mins (2)
    CL Item
    30 mins (3)
    CL Item
    1 hr (4)
    CL Item
    2 hr (5)
    CL Item
    4 hr (6)
    CL Item
    8 hr (7)
    CL Item
    12 hr (8)
    CL Item
    12 hr:15 m (9)
    CL Item
    12 hr:30 m (10)
    CL Item
    13 hr (11)
    CL Item
    14 hr (12)
    CL Item
    16 hr (13)
    CL Item
    20 hr (14)
    CL Item
    24 hr (15)
    Item
    Please check if not done
    text
    C1272696 (UMLS CUI [1])
    Code List
    Please check if not done
    CL Item
    Not Done (ND)
    Date/ Time of assessment
    Item
    Date/ Time of assessment
    datetime
    C2985720 (UMLS CUI [1,1])
    C1264639 (UMLS CUI [1,2])
    Nose not runny/Nose extremely runny
    Item
    Nose not runny/Nose extremely runny
    integer
    C1260880 (UMLS CUI [1])
    Nose clear/Nose completely blocked
    Item
    Nose clear/Nose completely blocked
    integer
    C0027424 (UMLS CUI [1])
    Nose not itchy/Nose extremely itchy
    Item
    Nose not itchy/Nose extremely itchy
    integer
    C0850060 (UMLS CUI [1])
    Nose not sore/Nose as sore as it has ever been
    Item
    Nose not sore/Nose as sore as it has ever been
    integer
    C0857495 (UMLS CUI [1])
    Nose not dry/Nose as dry as it has ever been
    Item
    Nose not dry/Nose as dry as it has ever been
    integer
    C0231919 (UMLS CUI [1])
    Throat not sore/Throat as sore as it has ever been
    Item
    Throat not sore/Throat as sore as it has ever been
    integer
    C0242429 (UMLS CUI [1])
    Sense of taste normal/ Sense of taste completely abnormal
    Item
    Sense of taste normal/ Sense of taste completely abnormal
    integer
    C0039336 (UMLS CUI [1])
    Taste nothing/Taste something very strongly
    Item
    Taste nothing/Taste something very strongly
    integer
    C1301555 (UMLS CUI [1])
    Sense of smell normal/ Sense of smell completely abnormal
    Item
    Sense of smell normal/ Sense of smell completely abnormal
    integer
    C0037361 (UMLS CUI [1])
    Smell nothing/Smell something very strongly
    Item
    Smell nothing/Smell something very strongly
    integer
    C2712084 (UMLS CUI [1])
    Nasal symptom: (No symptoms/Worst symptoms I have ever had)
    Item
    Nasal symptom: (No symptoms/Worst symptoms I have ever had)
    integer
    C0231918 (UMLS CUI [1])
    Item
    Nasal symptom: (No symptoms/Worst symptoms I have ever had)
    text
    C0231918 (UMLS CUI [1])
    Code List
    Nasal symptom: (No symptoms/Worst symptoms I have ever had)
    CL Item
    No additional symptoms (NA)
    CL Item
    Specify symptom (?)
    Specify symptom
    Item
    Specify symptom
    text
    C1457887 (UMLS CUI [1,1])
    C2348235 (UMLS CUI [1,2])
    Item Group
    Visual Analogue Scale (Day 3 - Day 13)
    C2959685 (UMLS CUI-1)
    Item
    Day of assessment
    integer
    C2985720 (UMLS CUI [1])
    Code List
    Day of assessment
    CL Item
    Day 3 (1)
    CL Item
    Day 4 (2)
    CL Item
    Day 5 (3)
    CL Item
    Day 6 (4)
    CL Item
    Day 7 (5)
    CL Item
    Day 8 (6)
    CL Item
    Day 9 (7)
    CL Item
    Day 10 (8)
    CL Item
    Day 11 (9)
    CL Item
    Day 12 (10)
    CL Item
    Day 13 (11)
    AM Dosing date/ time
    Item
    AM Dosing date/ time
    datetime
    C0178602 (UMLS CUI [1,1])
    C1264639 (UMLS CUI [1,2])
    C4331833 (UMLS CUI [1,3])
    PM Dosing date/ time
    Item
    PM Dosing date/ time
    datetime
    C0178602 (UMLS CUI [1,1])
    C1264639 (UMLS CUI [1,2])
    C1509133 (UMLS CUI [1,3])
    Item
    Timepoint
    integer
    C2348792 (UMLS CUI [1])
    Code List
    Timepoint
    CL Item
    1 hr post AM dose (1)
    CL Item
    1 hr post PM dose (2)
    Date/ Time of assessment
    Item
    Date/ Time of assessment
    datetime
    C2985720 (UMLS CUI [1,1])
    C1264639 (UMLS CUI [1,2])
    Nose not runny/Nose extremely runny
    Item
    Nose not runny/Nose extremely runny
    integer
    C1260880 (UMLS CUI [1])
    Nose clear/Nose completely blocked
    Item
    Nose clear/Nose completely blocked
    integer
    C0027424 (UMLS CUI [1])
    Nose not itchy/Nose extremely itchy
    Item
    Nose not itchy/Nose extremely itchy
    integer
    C0850060 (UMLS CUI [1])
    Nose not sore/Nose as sore as it has ever been
    Item
    Nose not sore/Nose as sore as it has ever been
    integer
    C0857495 (UMLS CUI [1])
    Nose not dry/Nose as dry as it has ever been
    Item
    Nose not dry/Nose as dry as it has ever been
    integer
    C0231919 (UMLS CUI [1])
    Throat not sore/Throat as sore as it has ever been
    Item
    Throat not sore/Throat as sore as it has ever been
    integer
    C0242429 (UMLS CUI [1])
    Sense of taste normal/ Sense of taste completely abnormal
    Item
    Sense of taste normal/ Sense of taste completely abnormal
    integer
    C0039336 (UMLS CUI [1])
    Taste nothing/Taste something very strongly
    Item
    Taste nothing/Taste something very strongly
    integer
    C1301555 (UMLS CUI [1])
    Sense of smell normal/ Sense of smell completely abnormal
    Item
    Sense of smell normal/ Sense of smell completely abnormal
    integer
    C0037361 (UMLS CUI [1])
    Smell nothing/Smell something very strongly
    Item
    Smell nothing/Smell something very strongly
    integer
    C2712084 (UMLS CUI [1])
    Nasal symptom: (No symptoms/Worst symptoms I have ever had)
    Item
    Nasal symptom: (No symptoms/Worst symptoms I have ever had)
    integer
    C0231918 (UMLS CUI [1])
    Item
    Nasal symptom: (No symptoms/Worst symptoms I have ever had)
    text
    C0231918 (UMLS CUI [1])
    Code List
    Nasal symptom: (No symptoms/Worst symptoms I have ever had)
    CL Item
    No additional symptoms  (NA)
    CL Item
    Specify symptom (?)
    Specify symptom
    Item
    Specify symptom
    text
    C1457887 (UMLS CUI [1,1])
    C2348235 (UMLS CUI [1,2])
    Item Group
    Visual Analogue Scale - Dosing date/ time (Day 14 - 16)
    C2959685 (UMLS CUI-1)
    C0178602 (UMLS CUI-2)
    C1264639 (UMLS CUI-3)
    AM Dosing date/ time
    Item
    AM Dosing date/ time
    datetime
    C0178602 (UMLS CUI [1,1])
    C1264639 (UMLS CUI [1,2])
    C4331833 (UMLS CUI [1,3])
    PM Dosing date/ time
    Item
    PM Dosing date/ time
    datetime
    C0178602 (UMLS CUI [1,1])
    C1264639 (UMLS CUI [1,2])
    C1509133 (UMLS CUI [1,3])
    Item Group
    Visual Analogue Scale (Day 14 - 16)
    C2959685 (UMLS CUI-1)
    Item
    Timepoint
    integer
    C2348792 (UMLS CUI [1])
    Code List
    Timepoint
    CL Item
    Pre-dose (1)
    CL Item
    15 mins (2)
    CL Item
    30 mins (3)
    CL Item
    1 hr (4)
    CL Item
    2 hr (5)
    CL Item
    4 hr (6)
    CL Item
    8 hr (7)
    CL Item
    12 hr (9)
    CL Item
    12 hr:15 m (10)
    CL Item
    12 hr:30 m (11)
    CL Item
    13 hr (12)
    CL Item
    14 hr (13)
    CL Item
    16 hr (14)
    CL Item
    20 hr (15)
    CL Item
    24 hr (16)
    CL Item
    36 hr (17)
    CL Item
    48 hr (18)
    CL Item
    60 hr (19)
    Date/ Time of assessment
    Item
    Date/ Time of assessment
    datetime
    C2985720 (UMLS CUI [1,1])
    C1264639 (UMLS CUI [1,2])
    Nose not runny/Nose extremely runny
    Item
    Nose not runny/Nose extremely runny
    integer
    C1260880 (UMLS CUI [1])
    Nose clear/Nose completely blocked
    Item
    Nose clear/Nose completely blocked
    integer
    C0027424 (UMLS CUI [1])
    Nose not itchy/Nose extremely itchy
    Item
    Nose not itchy/Nose extremely itchy
    integer
    C0850060 (UMLS CUI [1])
    Nose not sore/Nose as sore as it has ever been
    Item
    Nose not sore/Nose as sore as it has ever been
    integer
    C0857495 (UMLS CUI [1])
    Nose not dry/Nose as dry as it has ever been
    Item
    Nose not dry/Nose as dry as it has ever been
    integer
    C0231919 (UMLS CUI [1])
    Throat not sore/Throat as sore as it has ever been
    Item
    Throat not sore/Throat as sore as it has ever been
    integer
    C0242429 (UMLS CUI [1])
    Sense of taste normal/ Sense of taste completely abnormal
    Item
    Sense of taste normal/ Sense of taste completely abnormal
    integer
    C0039336 (UMLS CUI [1])
    Taste nothing/Taste something very strongly
    Item
    Taste nothing/Taste something very strongly
    integer
    C1301555 (UMLS CUI [1])
    Sense of smell normal/ Sense of smell completely abnormal
    Item
    Sense of smell normal/ Sense of smell completely abnormal
    integer
    C0037361 (UMLS CUI [1])
    Smell nothing/Smell something very strongly
    Item
    Smell nothing/Smell something very strongly
    integer
    C2712084 (UMLS CUI [1])
    Nasal symptom: (No symptoms/Worst symptoms I have ever had)
    Item
    Nasal symptom: (No symptoms/Worst symptoms I have ever had)
    integer
    C0231918 (UMLS CUI [1])
    Item
    Nasal symptom: (No symptoms/Worst symptoms I have ever had)
    text
    C0231918 (UMLS CUI [1])
    Code List
    Nasal symptom: (No symptoms/Worst symptoms I have ever had)
    CL Item
    No additional symptoms  (NA)
    CL Item
    Specify symptom (?)
    Specify symptom
    Item
    Specify symptom
    text
    C1457887 (UMLS CUI [1,1])
    C2348235 (UMLS CUI [1,2])

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