ID
37507
Description
Study ID: 110269 Clinical Study ID: 110269 Study Title: An open label positron emission tomography study in healthy male subjects to investigate brain Dopamine D3 receptor occupancy, pharmacokinetics and safety of single oral doses of GSK618334, using 11C-PHNO as PET ligand Patient Level Data: Study Listed on ClinicalStudyDataRequest.com Clinicaltrials.gov Identifier: NCT00814957 Sponsor: GlaxoSmithKline Phase: Phase 1 Study Recruitment Status: Completed Generic Name: positron emission tomography, GSK618334 Study Indication: Substance Dependence
Keywords
Versions (2)
- 7/24/19 7/24/19 -
- 8/4/19 8/4/19 -
Copyright Holder
GlaxoSmithKline
Uploaded on
August 4, 2019
DOI
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License
Creative Commons BY-NC 3.0
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Brain Dopamine D3 receptor occupancy, pharmacokinetics and safety of single oral doses of GSK618334, using 11C-PHNO as PET ligand NCT00814957
Day -1 - PET; Functional MRI Scan
- StudyEvent: ODM
Description
PET - Scan 2
Alias
- UMLS CUI-1
- C0032743
Description
Date of PET Scan 2
Data type
date
Alias
- UMLS CUI [1,1]
- C0032743
- UMLS CUI [1,2]
- C0011008
Description
PET Scan 2 - Examination Number
Data type
integer
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C0582103
- UMLS CUI [2,2]
- C0237753
Description
PET Scan 2 - Radiochemical purity at release
Data type
integer
Measurement units
- %
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C0599914
- UMLS CUI [2,2]
- C0678739
- UMLS CUI [2,3]
- C1963578
- UMLS CUI [2,4]
- C0032743
Description
PET Scan 2 - Radiochemical purity time at release
Data type
time
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C0599914
- UMLS CUI [2,2]
- C0678739
- UMLS CUI [2,3]
- C0040223
- UMLS CUI [2,4]
- C1963578
- UMLS CUI [2,5]
- C0032743
Description
PET Scan 2 - Mass of tracer administered
Data type
float
Measurement units
- ug
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C1522485
- UMLS CUI [2,2]
- C0178602
- UMLS CUI [2,3]
- C0032743
Description
PET Scan 2 - Volume to be administered (inc diluent)
Data type
float
Measurement units
- mL
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C0449468
- UMLS CUI [2,2]
- C1533734
- UMLS CUI [2,3]
- C0032743
Description
PET Scan 2 - Bolus activity injected
Data type
float
Measurement units
- MBq/mL
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C2986768
- UMLS CUI [2,2]
- C0205177
- UMLS CUI [2,3]
- C0032743
Description
PET Scan 2 - Bolus injection Start time
Data type
time
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C1511237
- UMLS CUI [2,2]
- C1301880
- UMLS CUI [2,3]
- C0032743
Description
PET Scan 2 - Duration of bolus injection
Data type
durationDatetime
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C1511237
- UMLS CUI [2,2]
- C0449238
- UMLS CUI [2,3]
- C0032743
Description
PET Scan 2 - Constant infusion activity concentration (at start of infusion)
Data type
float
Measurement units
- MBq/mL
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C0574032
- UMLS CUI [2,2]
- C0205177
- UMLS CUI [2,3]
- C0032743
Description
PET Scan 2 - Constant infusion start time
Data type
time
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C0574032
- UMLS CUI [2,2]
- C1301880
- UMLS CUI [2,3]
- C0032743
Description
PET Scan 2 - Constant infusion stop time
Data type
time
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C0574032
- UMLS CUI [2,2]
- C1522314
- UMLS CUI [2,3]
- C0032743
Description
PET Scan 2 - Volume of constant infusion administered
Data type
float
Measurement units
- mL
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C0574032
- UMLS CUI [2,2]
- C0449468
- UMLS CUI [2,3]
- C0032743
Description
Functional MRI Scan
Alias
- UMLS CUI-1
- C0376335
Description
Has an fMRI scan been carried out?
Data type
boolean
Alias
- UMLS CUI [1]
- C0376335
Description
If fMRI has been carried out, enter date of fMRI Scan
Data type
date
Alias
- UMLS CUI [1,1]
- C0376335
- UMLS CUI [1,2]
- C0011008
Description
fMRI Examination Number
Data type
integer
Alias
- UMLS CUI [1,1]
- C0376335
- UMLS CUI [1,2]
- C0582103
- UMLS CUI [1,3]
- C0237753
Description
fMRI Scan start time
Data type
time
Alias
- UMLS CUI [1,1]
- C0376335
- UMLS CUI [1,2]
- C1301880
Description
fMRI Scan end time
Data type
time
Alias
- UMLS CUI [1,1]
- C0376335
- UMLS CUI [1,2]
- C1522314
Description
Leave blank if scan was without incident (e.g., ‘subject moved’, subject was coughing‘)
Data type
text
Alias
- UMLS CUI [1,1]
- C0376335
- UMLS CUI [1,2]
- C0205161
- UMLS CUI [1,3]
- C2745955
Description
PET - Scan 3
Alias
- UMLS CUI-1
- C0032743
Description
Date of PET Scan 3
Data type
date
Alias
- UMLS CUI [1,1]
- C0032743
- UMLS CUI [1,2]
- C0011008
Description
PET Scan 3 - Examination Number
Data type
integer
Alias
- UMLS CUI [1,1]
- C0032743
- UMLS CUI [1,2]
- C0582103
- UMLS CUI [1,3]
- C0237753
Description
PET Scan 3 - Radiochemical purity at release
Data type
integer
Measurement units
- %
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C0599914
- UMLS CUI [2,2]
- C0678739
- UMLS CUI [2,3]
- C1963578
- UMLS CUI [2,4]
- C0032743
Description
PET Scan 3 - Radiochemical purity time at release
Data type
time
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C0599914
- UMLS CUI [2,2]
- C0678739
- UMLS CUI [2,3]
- C0040223
- UMLS CUI [2,4]
- C1963578
- UMLS CUI [2,5]
- C0032743
Description
PET Scan 3 - Mass of tracer administered
Data type
float
Measurement units
- ug
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C1522485
- UMLS CUI [2,2]
- C0178602
- UMLS CUI [2,3]
- C0032743
Description
PET Scan 3 - Volume to be administered (inc diluent)
Data type
float
Measurement units
- mL
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C0449468
- UMLS CUI [2,2]
- C1533734
- UMLS CUI [2,3]
- C0032743
Description
PET Scan 3 - Bolus activity injected
Data type
float
Measurement units
- MBq/mL
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C2986768
- UMLS CUI [2,2]
- C0205177
- UMLS CUI [2,3]
- C0032743
Description
PET Scan 3 - Bolus injection Start time
Data type
time
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C1511237
- UMLS CUI [2,2]
- C1301880
- UMLS CUI [2,3]
- C0032743
Description
PET Scan 3 - Duration of bolus injection
Data type
durationDatetime
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C1511237
- UMLS CUI [2,2]
- C0449238
- UMLS CUI [2,3]
- C0032743
Description
PET Scan 3 - Constant infusion activity concentration (at start of infusion)
Data type
float
Measurement units
- MBq/mL
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C0574032
- UMLS CUI [2,2]
- C0205177
- UMLS CUI [2,3]
- C0032743
Description
PET Scan 3 - Constant infusion start time
Data type
time
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C0574032
- UMLS CUI [2,2]
- C1301880
- UMLS CUI [2,3]
- C0032743
Description
PET Scan 3 - Constant infusion stop time
Data type
time
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C0574032
- UMLS CUI [2,2]
- C1522314
- UMLS CUI [2,3]
- C0032743
Description
PET Scan 3 - Volume of constant infusion administered
Data type
float
Measurement units
- mL
Alias
- UMLS CUI [1]
- C0032743
- UMLS CUI [2,1]
- C0574032
- UMLS CUI [2,2]
- C0449468
- UMLS CUI [2,3]
- C0032743
Similar models
Day -1 - PET; Functional MRI Scan
- StudyEvent: ODM
C0011008 (UMLS CUI [1,2])
C0582103 (UMLS CUI [2,1])
C0237753 (UMLS CUI [2,2])
C0599914 (UMLS CUI [2,1])
C0678739 (UMLS CUI [2,2])
C1963578 (UMLS CUI [2,3])
C0032743 (UMLS CUI [2,4])
C0599914 (UMLS CUI [2,1])
C0678739 (UMLS CUI [2,2])
C0040223 (UMLS CUI [2,3])
C1963578 (UMLS CUI [2,4])
C0032743 (UMLS CUI [2,5])
C1522485 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C0032743 (UMLS CUI [2,3])
C0449468 (UMLS CUI [2,1])
C1533734 (UMLS CUI [2,2])
C0032743 (UMLS CUI [2,3])
C2986768 (UMLS CUI [2,1])
C0205177 (UMLS CUI [2,2])
C0032743 (UMLS CUI [2,3])
C1511237 (UMLS CUI [2,1])
C1301880 (UMLS CUI [2,2])
C0032743 (UMLS CUI [2,3])
C1511237 (UMLS CUI [2,1])
C0449238 (UMLS CUI [2,2])
C0032743 (UMLS CUI [2,3])
C0574032 (UMLS CUI [2,1])
C0205177 (UMLS CUI [2,2])
C0032743 (UMLS CUI [2,3])
C0574032 (UMLS CUI [2,1])
C1301880 (UMLS CUI [2,2])
C0032743 (UMLS CUI [2,3])
C0574032 (UMLS CUI [2,1])
C1522314 (UMLS CUI [2,2])
C0032743 (UMLS CUI [2,3])
C0574032 (UMLS CUI [2,1])
C0449468 (UMLS CUI [2,2])
C0032743 (UMLS CUI [2,3])
C0011008 (UMLS CUI [1,2])
C0582103 (UMLS CUI [1,2])
C0237753 (UMLS CUI [1,3])
C1301880 (UMLS CUI [1,2])
C1522314 (UMLS CUI [1,2])
C0205161 (UMLS CUI [1,2])
C2745955 (UMLS CUI [1,3])
C0011008 (UMLS CUI [1,2])
C0582103 (UMLS CUI [1,2])
C0237753 (UMLS CUI [1,3])
C0599914 (UMLS CUI [2,1])
C0678739 (UMLS CUI [2,2])
C1963578 (UMLS CUI [2,3])
C0032743 (UMLS CUI [2,4])
C0599914 (UMLS CUI [2,1])
C0678739 (UMLS CUI [2,2])
C0040223 (UMLS CUI [2,3])
C1963578 (UMLS CUI [2,4])
C0032743 (UMLS CUI [2,5])
C1522485 (UMLS CUI [2,1])
C0178602 (UMLS CUI [2,2])
C0032743 (UMLS CUI [2,3])
C0449468 (UMLS CUI [2,1])
C1533734 (UMLS CUI [2,2])
C0032743 (UMLS CUI [2,3])
C2986768 (UMLS CUI [2,1])
C0205177 (UMLS CUI [2,2])
C0032743 (UMLS CUI [2,3])
C1511237 (UMLS CUI [2,1])
C1301880 (UMLS CUI [2,2])
C0032743 (UMLS CUI [2,3])
C1511237 (UMLS CUI [2,1])
C0449238 (UMLS CUI [2,2])
C0032743 (UMLS CUI [2,3])
C0574032 (UMLS CUI [2,1])
C0205177 (UMLS CUI [2,2])
C0032743 (UMLS CUI [2,3])
C0574032 (UMLS CUI [2,1])
C1301880 (UMLS CUI [2,2])
C0032743 (UMLS CUI [2,3])
C0574032 (UMLS CUI [2,1])
C1522314 (UMLS CUI [2,2])
C0032743 (UMLS CUI [2,3])
C0574032 (UMLS CUI [2,1])
C0449468 (UMLS CUI [2,2])
C0032743 (UMLS CUI [2,3])