0 Beoordelingen

ID

37371

Beschrijving

Study ID: 111592 Clinical Study ID: 111592 Study Title: A Randomized, Double-blind, Placebo-controlled, Doseescalation Study to Assess the Anti-inflammatory Activity, Efficacy, and Safety of Intravenous SB-681323 in Subjects at Risk for Development of Acute Lung Injury or ARDS Patient Level Data: Study Listed on ClinicalStudyDataRequest.com Clinicaltrials.gov Identifier: NCT00996840 See https://clinicaltrials.gov/ct2/show/NCT00996840 Sponsor: GlaxoSmithKline Collaborators: N/A Phase: Phase 2 Study Recruitment Status: Completed Generic Name: Placebo, SB-681323 Trade Name: N/A Study Indication: Lung Injury, Acute The primary objective of this phase 2 trial is to evaluate the safety and tolerability of intravenous dilmapimod/SB-681323 given in escalating dosages and over different intervals for three days in trauma patients at risk for the development of ALI or ARDS. This study consists of Screening, infusion of dilmapimod/SB-681323 on days 1-3, examination/sampling up to early day 5 (denoted as "Day 3 - 48 hrs") and a Follow-up on day 7. There are four cohorts, cohorts 1 and 3 receive the medication (or placebo) infusion over 4 hours, cohorts 2 and 4 over 24 hours. This form is to be filled in whenever an ECG reading is abnormal.

Link

https://clinicaltrials.gov/ct2/show/NCT00996840

Trefwoorden

  1. 20-07-19 20-07-19 -
Houder van rechten

GlaxoSmithKline

Geüploaded op

20 juli 2019

DOI

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Licentie

Creative Commons BY-NC 3.0

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    SB-681323 in ALI/ARDS risk patients - NCT00996840

    ECG Abnormalities

    1. StudyEvent: ODM
      1. ECG Abnormalities
    12-Lead ECG Abnormalities Administrative Data
    Beschrijving

    12-Lead ECG Abnormalities Administrative Data

    Alias
    UMLS CUI-1
    C0430456
    UMLS CUI-2
    C1704258
    UMLS CUI-3
    C1320722
    Date and Time of ECG
    Beschrijving

    Date/Time of ECG

    Datatype

    text

    Alias
    UMLS CUI [1,1]
    C0013798
    UMLS CUI [1,2]
    C1264639
    Subject Number
    Beschrijving

    Subject Number

    Datatype

    integer

    Alias
    UMLS CUI [1]
    C2348585
    Rhythm
    Beschrijving

    Rhythm

    Alias
    UMLS CUI-1
    C0232187
    Sinus bradycardia
    Beschrijving

    Sinus bradycardia

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0085610
    Sinus bradycardia (heart rate 40-50 beats/min)
    Beschrijving

    Sinus bradycardia (heart rate 40-50 beats/min)

    Datatype

    boolean

    Alias
    UMLS CUI [1,1]
    C0085610
    UMLS CUI [1,2]
    C0018810
    Sinus bradycardia (heart rate 30-39 beats/min)
    Beschrijving

    Sinus bradycardia (heart rate 30-39 beats/min)

    Datatype

    boolean

    Alias
    UMLS CUI [1,1]
    C0085610
    UMLS CUI [1,2]
    C0018810
    Sinus bradycardia (heart rate <30 beats/min)
    Beschrijving

    Sinus bradycardia (heart rate <30 beats/min)

    Datatype

    boolean

    Alias
    UMLS CUI [1,1]
    C0085610
    UMLS CUI [1,2]
    C0018810
    Sinus pause
    Beschrijving

    Sinus pause

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C1955864
    Sinus tachycardia (heart rate> 100 beats/min)
    Beschrijving

    Sinus tachycardia

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0039239
    Ectopic supraventricular beats
    Beschrijving

    Ectopic supraventricular beats

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0033036
    Ectopic supraventricular rhythm
    Beschrijving

    Ectopic supraventricular rhythm

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C2348376
    Wandering atrial pacemaker
    Beschrijving

    Wandering atrial pacemaker

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C1321523
    Multifocal atrial tachycardia (wandering atrial pacemaker with heart rate > 100 beats/min)
    Beschrijving

    Multifocal atrial tachycardia

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0221158
    Supraventricular tachycardia (heart rate > 100 beats/min)
    Beschrijving

    Supraventricular tachycardia

    Datatype

    boolean

    Alias
    UMLS CUI [1,1]
    C0039240
    UMLS CUI [1,2]
    C0018810
    Atrial flutter
    Beschrijving

    Atrial flutter

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0004239
    Atrial fibrillation
    Beschrijving

    Atrial fibrillation

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0004238
    Junctional rhythm (heart rate <= 100 beats/min)
    Beschrijving

    Junctional rhythm (heart rate <= 100 beats/min)

    Datatype

    boolean

    Alias
    UMLS CUI [1,1]
    C0232208
    UMLS CUI [1,2]
    C0018810
    Junctional rhythm
    Beschrijving

    Junctional rhythm

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0232208
    Junctional tachycardia (heart rate > 100 beats/min)
    Beschrijving

    Junctional tachycardia

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0039235
    Ectopic ventricular beats
    Beschrijving

    Ectopic ventricular beats

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0151636
    Ventricular couplets
    Beschrijving

    Ventricular couplets

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0429001
    Bigeminy
    Beschrijving

    Bigeminy

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0262662
    Trigeminy
    Beschrijving

    Trigeminy

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0428999
    Electrical alternans
    Beschrijving

    Electrical alternans

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C1142551
    R on T phenomenon
    Beschrijving

    R on T phenomenon

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0877658
    Ventricular fibrillation
    Beschrijving

    Ventricular fibrillation

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0042510
    ldioventricular rhythm
    Beschrijving

    ldioventricular rhythm

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0700363
    Sustained ventricular tachycardia
    Beschrijving

    Sustained ventricular tachycardia

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0750197
    Non-sustained ventricular tachycardia
    Beschrijving

    Non-sustained ventricular tachycardia

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0750194
    Wide QRS tachycardia (diagnosis unknown)
    Beschrijving

    Wide QRS tachycardia

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0344429
    Ventricular tachycardia
    Beschrijving

    Ventricular tachycardia

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0042514
    Monomorphic ventricular tachycardia
    Beschrijving

    Monomorphic ventricular tachycardia

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0344431
    Torsades de Pointes (Polymorphic ventricular tachycardia with prolonged QT)
    Beschrijving

    Torsades de Pointes

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0040479
    Polymorphic (sustained and non-sustained) ventricular tachycardia
    Beschrijving

    Polymorphic ventricular tachycardia

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0344432
    Artificial Pacemaker
    Beschrijving

    Artificial Pacemaker

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0030163
    Other abnormal rhythm
    Beschrijving

    Please enter comment

    Datatype

    boolean

    Alias
    UMLS CUI [1,1]
    C0205394
    UMLS CUI [1,2]
    C0199556
    UMLS CUI [1,3]
    C0205161
    If other abnormal rhythm, please specify
    Beschrijving

    Comment abnormal rhythm

    Datatype

    text

    Alias
    UMLS CUI [1,1]
    C0947611
    UMLS CUI [1,2]
    C0199556
    UMLS CUI [1,3]
    C0205161
    P-Wave and QRS Morphology
    Beschrijving

    P-Wave and QRS Morphology

    Alias
    UMLS CUI-1
    C0429072
    UMLS CUI-2
    C0429098
    Left atrial abnormality (P mitrale)
    Beschrijving

    Left atrial abnormality (P mitrale)

    Datatype

    boolean

    Alias
    UMLS CUI [1,1]
    C0344711
    UMLS CUI [1,2]
    C0232310
    Right atrial abnormality (P pulmonale)
    Beschrijving

    Right atrial abnormality (P pulmonale)

    Datatype

    boolean

    Alias
    UMLS CUI [1,1]
    C0344696
    UMLS CUI [1,2]
    C0232308
    Right ventricular hypertrophy
    Beschrijving

    Right ventricular hypertrophy

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0162770
    Intraatrial conduction delay
    Beschrijving

    Intraatrial conduction delay

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C2346510
    Increased voltage consistent with left ventricular hypertrophy
    Beschrijving

    Increased voltage consistent with left ventricular hypertrophy

    Datatype

    boolean

    Alias
    UMLS CUI [1,1]
    C1112650
    UMLS CUI [1,2]
    C0332290
    UMLS CUI [1,3]
    C0149721
    Other morphology
    Beschrijving

    Other morphology

    Datatype

    boolean

    Alias
    UMLS CUI [1,1]
    C0205394
    UMLS CUI [1,2]
    C0332437
    If other morphology, please specify
    Beschrijving

    Comment other morphology

    Datatype

    text

    Alias
    UMLS CUI [1,1]
    C0332437
    UMLS CUI [1,2]
    C0205394
    UMLS CUI [1,3]
    C0947611
    Conduction
    Beschrijving

    Conduction

    Alias
    UMLS CUI-1
    C0264886
    First degree AV block (PR interval> 200msec)
    Beschrijving

    First degree AV block

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0085614
    Short PR interval
    Beschrijving

    Short PR interval

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0520878
    Second degree AV block (Mobitz type 1)
    Beschrijving

    Second degree AV block (Mobitz type 1)

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0264907
    Second degree AV block (Mobitz type 2)
    Beschrijving

    Second degree AV block (Mobitz type 2)

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0155700
    2: 1 AV block
    Beschrijving

    2: 1 AV block

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C2346542
    Third degree AV block
    Beschrijving

    Third degree AV block

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0151517
    Left axis deviation (QRS axis more negative than -30 degrees)
    Beschrijving

    Left axis deviation

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0232297
    Right axis deviation (QRS axis more positive than +110 degrees)
    Beschrijving

    Right axis deviation

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0232296
    Incomplete right bundle branch block
    Beschrijving

    Incomplete right bundle branch block

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0262525
    Incomplete left bundle branch block
    Beschrijving

    Incomplete left bundle branch block

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0281878
    Right bundle branch block
    Beschrijving

    Right bundle branch block

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0085615
    Left anterior hemiblock
    Beschrijving

    synonymous to left anterior fascicular block

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0264912
    Left posterior hemiblock
    Beschrijving

    synonymous to left posterior fascicular block

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0264913
    Left bundle branch block
    Beschrijving

    Left bundle branch block

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0023211
    Bifascicular block
    Beschrijving

    Bifascicular block

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0264914
    Non-specific intraventricular conduction delay (QRS >= 120 msec)
    Beschrijving

    Non-specific intraventricular conduction delay

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C3697597
    Accessory pathway (Wolff-Parkinson White, Lown-Ganong-Levine)
    Beschrijving

    Accessory pathway in Wolff-Parkinson White/Lown-Ganong-Levine Syndrome

    Datatype

    boolean

    Alias
    UMLS CUI [1,1]
    C1963785
    UMLS CUI [1,2]
    C0043202
    UMLS CUI [2,1]
    C1963785
    UMLS CUI [2,2]
    C0024054
    Prolonged QT interval
    Beschrijving

    Prolonged QT interval

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0151878
    QT/QTc prolongation >=500msec
    Beschrijving

    QT/QTc prolongation by QTc time

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0855333
    UMLS CUI [2]
    C0489625
    AV dissociation
    Beschrijving

    AV dissociation

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0004331
    Other conduction abnormality
    Beschrijving

    Enter comment

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0340494
    If other conduction abnormality, please specify
    Beschrijving

    Comment other conduction abnormality

    Datatype

    text

    Alias
    UMLS CUI [1,1]
    C0340494
    UMLS CUI [1,2]
    C0947611
    Myocardial Infarction
    Beschrijving

    Myocardial Infarction

    Alias
    UMLS CUI-1
    C0027051
    Myocardial infarction, old
    Beschrijving

    Myocardial infarction, old

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0155668
    Myocardial infarction, anterior
    Beschrijving

    Myocardial infarction, anterior

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0340293
    Myocardial infarction, lateral
    Beschrijving

    Myocardial infarction, lateral

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0340312
    Myocardial infarction, posterior
    Beschrijving

    Myocardial infarction, posterior

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0340319
    Myocardial infarction, inferior
    Beschrijving

    Myocardial infarction, inferior

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0340305
    Myocardial infarction, septal
    Beschrijving

    Myocardial infarction, septal

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0746727
    Myocardial infarction, Non Q-wave
    Beschrijving

    Myocardial infarction, Non Q-wave

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0542269
    Other myocardial infarction
    Beschrijving

    Other myocardial infarction

    Datatype

    boolean

    Alias
    UMLS CUI [1,1]
    C0205394
    UMLS CUI [1,2]
    C0027051
    If other myocardial infarction, please specify
    Beschrijving

    Comment other myocardial infarction

    Datatype

    text

    Alias
    UMLS CUI [1,1]
    C0205394
    UMLS CUI [1,2]
    C0027051
    UMLS CUI [1,3]
    C0947611
    Depolarisation/Repolarisation (QRS-T)
    Beschrijving

    Depolarisation/Repolarisation (QRS-T)

    Alias
    UMLS CUI-1
    C2746082
    UMLS CUI-3
    C3537202
    Non-specific ST-T changes
    Beschrijving

    Non-specific ST-T changes

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C1112720
    J point elevation
    Beschrijving

    J point elevation

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C2346597
    ST elevation
    Beschrijving

    ST elevation

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0520886
    ST-elevation - pericarditis
    Beschrijving

    ST-elevation - pericarditis

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C2348119
    ST depression
    Beschrijving

    ST depression

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0520887
    U waves abnormal
    Beschrijving

    U waves abnormal

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0438169
    T wave inversion
    Beschrijving

    T wave inversion

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0520888
    T wave peaked
    Beschrijving

    T wave peaked

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0239242
    T waves flat
    Beschrijving

    T waves flat

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C2215959
    T waves biphasic
    Beschrijving

    T waves biphasic

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C2348639
    Notched T-waves
    Beschrijving

    Notched T-waves

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C2347367
    Low QRS voltage
    Beschrijving

    Low QRS voltage

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C2349945
    T-wave flattening/inversion
    Beschrijving

    T-wave flattening/inversion

    Datatype

    boolean

    Alias
    UMLS CUI [1]
    C0520888
    UMLS CUI [2]
    C0429059
    Other depolarisation/repolarisation abnormality
    Beschrijving

    Other depolarisation/repolarisation abnormality

    Datatype

    boolean

    Alias
    UMLS CUI [1,1]
    C0205394
    UMLS CUI [1,2]
    C0205161
    UMLS CUI [1,3]
    C2746082
    UMLS CUI [2,1]
    C0205394
    UMLS CUI [2,2]
    C0948857
    If other depolarisation/repolarisation, please specify
    Beschrijving

    Comment other depolarisation/repolarisation

    Datatype

    text

    Alias
    UMLS CUI [1,1]
    C0205394
    UMLS CUI [1,2]
    C0205161
    UMLS CUI [1,3]
    C2746082
    UMLS CUI [1,4]
    C0947611
    UMLS CUI [2,1]
    C0205394
    UMLS CUI [2,2]
    C0948857
    UMLS CUI [2,3]
    C0947611
    Other ECG abnormalities
    Beschrijving

    Other ECG abnormalities

    Alias
    UMLS CUI-1
    C0522055
    UMLS CUI-2
    C0205394
    Other abnormalities
    Beschrijving

    Enter comment

    Datatype

    boolean

    Alias
    UMLS CUI [1,1]
    C0522055
    UMLS CUI [1,2]
    C0205394
    Other ECG abnormalities comment
    Beschrijving

    Other ECG abnormalities comment

    Datatype

    text

    Alias
    UMLS CUI [1,1]
    C0522055
    UMLS CUI [1,2]
    C3845569
    UMLS CUI [1,3]
    C0947611

    Similar models

    ECG Abnormalities

    1. StudyEvent: ODM
      1. ECG Abnormalities
    Name
    Type
    Description | Question | Decode (Coded Value)
    Datatype
    Alias
    Item Group
    12-Lead ECG Abnormalities Administrative Data
    C0430456 (UMLS CUI-1)
    C1704258 (UMLS CUI-2)
    C1320722 (UMLS CUI-3)
    Date/Time of ECG
    Item
    Date and Time of ECG
    text
    C0013798 (UMLS CUI [1,1])
    C1264639 (UMLS CUI [1,2])
    Subject Number
    Item
    Subject Number
    integer
    C2348585 (UMLS CUI [1])
    Item Group
    Rhythm
    C0232187 (UMLS CUI-1)
    Sinus bradycardia
    Item
    Sinus bradycardia
    boolean
    C0085610 (UMLS CUI [1])
    Sinus bradycardia (heart rate 40-50 beats/min)
    Item
    Sinus bradycardia (heart rate 40-50 beats/min)
    boolean
    C0085610 (UMLS CUI [1,1])
    C0018810 (UMLS CUI [1,2])
    Sinus bradycardia (heart rate 30-39 beats/min)
    Item
    Sinus bradycardia (heart rate 30-39 beats/min)
    boolean
    C0085610 (UMLS CUI [1,1])
    C0018810 (UMLS CUI [1,2])
    Sinus bradycardia (heart rate <30 beats/min)
    Item
    Sinus bradycardia (heart rate <30 beats/min)
    boolean
    C0085610 (UMLS CUI [1,1])
    C0018810 (UMLS CUI [1,2])
    Sinus pause
    Item
    Sinus pause
    boolean
    C1955864 (UMLS CUI [1])
    Sinus tachycardia
    Item
    Sinus tachycardia (heart rate> 100 beats/min)
    boolean
    C0039239 (UMLS CUI [1])
    Ectopic supraventricular beats
    Item
    Ectopic supraventricular beats
    boolean
    C0033036 (UMLS CUI [1])
    Ectopic supraventricular rhythm
    Item
    Ectopic supraventricular rhythm
    boolean
    C2348376 (UMLS CUI [1])
    Wandering atrial pacemaker
    Item
    Wandering atrial pacemaker
    boolean
    C1321523 (UMLS CUI [1])
    Multifocal atrial tachycardia
    Item
    Multifocal atrial tachycardia (wandering atrial pacemaker with heart rate > 100 beats/min)
    boolean
    C0221158 (UMLS CUI [1])
    Supraventricular tachycardia
    Item
    Supraventricular tachycardia (heart rate > 100 beats/min)
    boolean
    C0039240 (UMLS CUI [1,1])
    C0018810 (UMLS CUI [1,2])
    Atrial flutter
    Item
    Atrial flutter
    boolean
    C0004239 (UMLS CUI [1])
    Atrial fibrillation
    Item
    Atrial fibrillation
    boolean
    C0004238 (UMLS CUI [1])
    Junctional rhythm (heart rate <= 100 beats/min)
    Item
    Junctional rhythm (heart rate <= 100 beats/min)
    boolean
    C0232208 (UMLS CUI [1,1])
    C0018810 (UMLS CUI [1,2])
    Junctional rhythm
    Item
    Junctional rhythm
    boolean
    C0232208 (UMLS CUI [1])
    Junctional tachycardia
    Item
    Junctional tachycardia (heart rate > 100 beats/min)
    boolean
    C0039235 (UMLS CUI [1])
    Ectopic ventricular beats
    Item
    Ectopic ventricular beats
    boolean
    C0151636 (UMLS CUI [1])
    Ventricular couplets
    Item
    Ventricular couplets
    boolean
    C0429001 (UMLS CUI [1])
    Bigeminy
    Item
    Bigeminy
    boolean
    C0262662 (UMLS CUI [1])
    Trigeminy
    Item
    Trigeminy
    boolean
    C0428999 (UMLS CUI [1])
    Electrical alternans
    Item
    Electrical alternans
    boolean
    C1142551 (UMLS CUI [1])
    R on T phenomenon
    Item
    R on T phenomenon
    boolean
    C0877658 (UMLS CUI [1])
    Ventricular fibrillation
    Item
    Ventricular fibrillation
    boolean
    C0042510 (UMLS CUI [1])
    ldioventricular rhythm
    Item
    ldioventricular rhythm
    boolean
    C0700363 (UMLS CUI [1])
    Sustained ventricular tachycardia
    Item
    Sustained ventricular tachycardia
    boolean
    C0750197 (UMLS CUI [1])
    Non-sustained ventricular tachycardia
    Item
    Non-sustained ventricular tachycardia
    boolean
    C0750194 (UMLS CUI [1])
    Wide QRS tachycardia
    Item
    Wide QRS tachycardia (diagnosis unknown)
    boolean
    C0344429 (UMLS CUI [1])
    Ventricular tachycardia
    Item
    Ventricular tachycardia
    boolean
    C0042514 (UMLS CUI [1])
    Monomorphic ventricular tachycardia
    Item
    Monomorphic ventricular tachycardia
    boolean
    C0344431 (UMLS CUI [1])
    Torsades de Pointes
    Item
    Torsades de Pointes (Polymorphic ventricular tachycardia with prolonged QT)
    boolean
    C0040479 (UMLS CUI [1])
    Polymorphic ventricular tachycardia
    Item
    Polymorphic (sustained and non-sustained) ventricular tachycardia
    boolean
    C0344432 (UMLS CUI [1])
    Artificial Pacemaker
    Item
    Artificial Pacemaker
    boolean
    C0030163 (UMLS CUI [1])
    Other abnormal rhythm
    Item
    Other abnormal rhythm
    boolean
    C0205394 (UMLS CUI [1,1])
    C0199556 (UMLS CUI [1,2])
    C0205161 (UMLS CUI [1,3])
    Comment abnormal rhythm
    Item
    If other abnormal rhythm, please specify
    text
    C0947611 (UMLS CUI [1,1])
    C0199556 (UMLS CUI [1,2])
    C0205161 (UMLS CUI [1,3])
    Item Group
    P-Wave and QRS Morphology
    C0429072 (UMLS CUI-1)
    C0429098 (UMLS CUI-2)
    Left atrial abnormality (P mitrale)
    Item
    Left atrial abnormality (P mitrale)
    boolean
    C0344711 (UMLS CUI [1,1])
    C0232310 (UMLS CUI [1,2])
    Right atrial abnormality (P pulmonale)
    Item
    Right atrial abnormality (P pulmonale)
    boolean
    C0344696 (UMLS CUI [1,1])
    C0232308 (UMLS CUI [1,2])
    Right ventricular hypertrophy
    Item
    Right ventricular hypertrophy
    boolean
    C0162770 (UMLS CUI [1])
    Intraatrial conduction delay
    Item
    Intraatrial conduction delay
    boolean
    C2346510 (UMLS CUI [1])
    Increased voltage consistent with left ventricular hypertrophy
    Item
    Increased voltage consistent with left ventricular hypertrophy
    boolean
    C1112650 (UMLS CUI [1,1])
    C0332290 (UMLS CUI [1,2])
    C0149721 (UMLS CUI [1,3])
    Other morphology
    Item
    Other morphology
    boolean
    C0205394 (UMLS CUI [1,1])
    C0332437 (UMLS CUI [1,2])
    Comment other morphology
    Item
    If other morphology, please specify
    text
    C0332437 (UMLS CUI [1,1])
    C0205394 (UMLS CUI [1,2])
    C0947611 (UMLS CUI [1,3])
    Item Group
    Conduction
    C0264886 (UMLS CUI-1)
    First degree AV block
    Item
    First degree AV block (PR interval> 200msec)
    boolean
    C0085614 (UMLS CUI [1])
    Short PR interval
    Item
    Short PR interval
    boolean
    C0520878 (UMLS CUI [1])
    Second degree AV block (Mobitz type 1)
    Item
    Second degree AV block (Mobitz type 1)
    boolean
    C0264907 (UMLS CUI [1])
    Second degree AV block (Mobitz type 2)
    Item
    Second degree AV block (Mobitz type 2)
    boolean
    C0155700 (UMLS CUI [1])
    2: 1 AV block
    Item
    2: 1 AV block
    boolean
    C2346542 (UMLS CUI [1])
    Third degree AV block
    Item
    Third degree AV block
    boolean
    C0151517 (UMLS CUI [1])
    Left axis deviation
    Item
    Left axis deviation (QRS axis more negative than -30 degrees)
    boolean
    C0232297 (UMLS CUI [1])
    Right axis deviation
    Item
    Right axis deviation (QRS axis more positive than +110 degrees)
    boolean
    C0232296 (UMLS CUI [1])
    Incomplete right bundle branch block
    Item
    Incomplete right bundle branch block
    boolean
    C0262525 (UMLS CUI [1])
    Incomplete left bundle branch block
    Item
    Incomplete left bundle branch block
    boolean
    C0281878 (UMLS CUI [1])
    Right bundle branch block
    Item
    Right bundle branch block
    boolean
    C0085615 (UMLS CUI [1])
    Left anterior hemiblock
    Item
    Left anterior hemiblock
    boolean
    C0264912 (UMLS CUI [1])
    Left posterior hemiblock
    Item
    Left posterior hemiblock
    boolean
    C0264913 (UMLS CUI [1])
    Left bundle branch block
    Item
    Left bundle branch block
    boolean
    C0023211 (UMLS CUI [1])
    Bifascicular block
    Item
    Bifascicular block
    boolean
    C0264914 (UMLS CUI [1])
    Non-specific intraventricular conduction delay
    Item
    Non-specific intraventricular conduction delay (QRS >= 120 msec)
    boolean
    C3697597 (UMLS CUI [1])
    Accessory pathway in Wolff-Parkinson White/Lown-Ganong-Levine Syndrome
    Item
    Accessory pathway (Wolff-Parkinson White, Lown-Ganong-Levine)
    boolean
    C1963785 (UMLS CUI [1,1])
    C0043202 (UMLS CUI [1,2])
    C1963785 (UMLS CUI [2,1])
    C0024054 (UMLS CUI [2,2])
    Prolonged QT interval
    Item
    Prolonged QT interval
    boolean
    C0151878 (UMLS CUI [1])
    QT/QTc prolongation by QTc time
    Item
    QT/QTc prolongation >=500msec
    boolean
    C0855333 (UMLS CUI [1])
    C0489625 (UMLS CUI [2])
    AV dissociation
    Item
    AV dissociation
    boolean
    C0004331 (UMLS CUI [1])
    Other conduction abnormality
    Item
    Other conduction abnormality
    boolean
    C0340494 (UMLS CUI [1])
    Comment other conduction abnormality
    Item
    If other conduction abnormality, please specify
    text
    C0340494 (UMLS CUI [1,1])
    C0947611 (UMLS CUI [1,2])
    Item Group
    Myocardial Infarction
    C0027051 (UMLS CUI-1)
    Myocardial infarction, old
    Item
    Myocardial infarction, old
    boolean
    C0155668 (UMLS CUI [1])
    Myocardial infarction, anterior
    Item
    Myocardial infarction, anterior
    boolean
    C0340293 (UMLS CUI [1])
    Myocardial infarction, lateral
    Item
    Myocardial infarction, lateral
    boolean
    C0340312 (UMLS CUI [1])
    Myocardial infarction, posterior
    Item
    Myocardial infarction, posterior
    boolean
    C0340319 (UMLS CUI [1])
    Myocardial infarction, inferior
    Item
    Myocardial infarction, inferior
    boolean
    C0340305 (UMLS CUI [1])
    Myocardial infarction, septal
    Item
    Myocardial infarction, septal
    boolean
    C0746727 (UMLS CUI [1])
    Myocardial infarction, Non Q-wave
    Item
    Myocardial infarction, Non Q-wave
    boolean
    C0542269 (UMLS CUI [1])
    Other myocardial infarction
    Item
    Other myocardial infarction
    boolean
    C0205394 (UMLS CUI [1,1])
    C0027051 (UMLS CUI [1,2])
    Comment other myocardial infarction
    Item
    If other myocardial infarction, please specify
    text
    C0205394 (UMLS CUI [1,1])
    C0027051 (UMLS CUI [1,2])
    C0947611 (UMLS CUI [1,3])
    Item Group
    Depolarisation/Repolarisation (QRS-T)
    C2746082 (UMLS CUI-1)
    C3537202 (UMLS CUI-3)
    Non-specific ST-T changes
    Item
    Non-specific ST-T changes
    boolean
    C1112720 (UMLS CUI [1])
    J point elevation
    Item
    J point elevation
    boolean
    C2346597 (UMLS CUI [1])
    ST elevation
    Item
    ST elevation
    boolean
    C0520886 (UMLS CUI [1])
    ST-elevation - pericarditis
    Item
    ST-elevation - pericarditis
    boolean
    C2348119 (UMLS CUI [1])
    ST depression
    Item
    ST depression
    boolean
    C0520887 (UMLS CUI [1])
    U waves abnormal
    Item
    U waves abnormal
    boolean
    C0438169 (UMLS CUI [1])
    T wave inversion
    Item
    T wave inversion
    boolean
    C0520888 (UMLS CUI [1])
    T wave peaked
    Item
    T wave peaked
    boolean
    C0239242 (UMLS CUI [1])
    T waves flat
    Item
    T waves flat
    boolean
    C2215959 (UMLS CUI [1])
    T waves biphasic
    Item
    T waves biphasic
    boolean
    C2348639 (UMLS CUI [1])
    Notched T-waves
    Item
    Notched T-waves
    boolean
    C2347367 (UMLS CUI [1])
    Low QRS voltage
    Item
    Low QRS voltage
    boolean
    C2349945 (UMLS CUI [1])
    T-wave flattening/inversion
    Item
    T-wave flattening/inversion
    boolean
    C0520888 (UMLS CUI [1])
    C0429059 (UMLS CUI [2])
    Other depolarisation/repolarisation abnormality
    Item
    Other depolarisation/repolarisation abnormality
    boolean
    C0205394 (UMLS CUI [1,1])
    C0205161 (UMLS CUI [1,2])
    C2746082 (UMLS CUI [1,3])
    C0205394 (UMLS CUI [2,1])
    C0948857 (UMLS CUI [2,2])
    Comment other depolarisation/repolarisation
    Item
    If other depolarisation/repolarisation, please specify
    text
    C0205394 (UMLS CUI [1,1])
    C0205161 (UMLS CUI [1,2])
    C2746082 (UMLS CUI [1,3])
    C0947611 (UMLS CUI [1,4])
    C0205394 (UMLS CUI [2,1])
    C0948857 (UMLS CUI [2,2])
    C0947611 (UMLS CUI [2,3])
    Item Group
    Other ECG abnormalities
    C0522055 (UMLS CUI-1)
    C0205394 (UMLS CUI-2)
    Other abnormalities
    Item
    Other abnormalities
    boolean
    C0522055 (UMLS CUI [1,1])
    C0205394 (UMLS CUI [1,2])
    Other ECG abnormalities comment
    Item
    Other ECG abnormalities comment
    text
    C0522055 (UMLS CUI [1,1])
    C3845569 (UMLS CUI [1,2])
    C0947611 (UMLS CUI [1,3])

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