ID

25186

Description

Diary Card - Varicella /Zoster Case - GSK Study: Evaluation of safety and efficacy of VarilrixTM and of Combined Measles-Mumps-Rubella-Varicella Vaccine NCT00226499 Study ID: 100388 Clinical Study ID: 100388 Study Title: Study in Healthy Children (<2 Years) to Evaluate the Safety and Efficacy of GSK Biologicals' Live Attenuated Varicella Vaccine (VarilrixTM) and of GSK Biologicals' Combined Measles-Mumps-Rubella-Varicella Vaccine Patient Level Data: Study Listed on ClinicalStudyDataRequest.com Clinicaltrials.gov Identifier: NCT00226499 Sponsor: GlaxoSmithKline Collaborators: N/A Phase: phase 3 Study Recruitment Status: Completed Generic Name: Varicella Vaccine Trade Name: BIO OKAH; Varilrix Study Indication: Varicella

Keywords

Versions (1)
  1. 8/28/17 8/28/17 -
Copyright Holder

glaxoSmithKline

Uploaded on

August 28, 2017

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License

Creative Commons BY-NC 3.0
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    Diary Card - Varicella /Zoster Case - GSK Study: Evaluation of safety and efficacy of VarilrixTM and of Combined Measles-Mumps-Rubella-Varicella Vaccine NCT00226499

    English

    Diary Card - Varicella /Zoster Case - GSK Study: Evaluation of safety and efficacy of VarilrixTM and of Combined Measles-Mumps-Rubella-Varicella Vaccine NCT00226499

    1 forms  
    Rash
    Description

    Rash

    Alias
    UMLS CUI-1
    C0015230
    Date rash onset
    Description

    date when first lesion appears

    Data type

    date

    Alias
    UMLS CUI [1,1]
    C0015230
    UMLS CUI [1,2]
    C0574845
    Date rash end
    Description

    date of first day when no new lesions appear

    Data type

    date

    Alias
    UMLS CUI [1,1]
    C0015230
    UMLS CUI [1,2]
    C0806020
    Lesion
    Description

    Lesion

    Alias
    UMLS CUI-1
    C0221198
    Day
    Description

    Day 0-14 Day 0 should be date rash onset - Complete until date rash end

    Data type

    integer

    Alias
    UMLS CUI [1,1]
    C0439228
    UMLS CUI [1,2]
    C0750480
    UMLS CUI [1,3]
    C0221198
    Daily number of overall Lesions
    Description

    Daily number of overall Lesions

    Data type

    integer

    Alias
    UMLS CUI [1,1]
    C0221198
    UMLS CUI [1,2]
    C0449788
    UMLS CUI [1,3]
    C0332173
    Vesicles
    Description

    Vesicles

    Alias
    UMLS CUI-1
    C0333262
    Day
    Description

    Day 0 should be date rash onset - Complete until date rash end

    Data type

    text

    Alias
    UMLS CUI [1,1]
    C0439228
    UMLS CUI [1,2]
    C0750480
    UMLS CUI [1,3]
    C0333262
    Daily number of overall Vesicles
    Description

    Estimation of the DAILY number of vesicles (=lesions with fluid in them) according to the following ranges

    Data type

    integer

    Alias
    UMLS CUI [1,1]
    C0333262
    UMLS CUI [1,2]
    C0449788
    UMLS CUI [1,3]
    C0332173
    Temperature
    Description

    Temperature

    Alias
    UMLS CUI-1
    C0039476
    Route
    Description

    Please record all temperatures from date rash onset till date rash end Note: → If multiple measurements during a day, record the highest temperature → Only one route of temperature measurement should be used consistently

    Data type

    text

    Alias
    UMLS CUI [1,1]
    C0005903
    UMLS CUI [1,2]
    C1515974
    Temperature
    Description

    Temperature

    Alias
    UMLS CUI-1
    C0039476
    Day
    Description

    Day 0-14 Please record all temperatures from date rash onset till date rash end Note: → If multiple measurements during a day, record the highest temperature → Only one route of temperature measurement should be used consistently

    Data type

    integer

    Alias
    UMLS CUI [1,1]
    C0439228
    UMLS CUI [1,2]
    C0750480
    UMLS CUI [1,3]
    C0039476
    Date
    Description

    Date Temperature

    Data type

    date

    Alias
    UMLS CUI [1,1]
    C0039476
    UMLS CUI [1,2]
    C0011008
    Temperature
    Description

    Temperature

    Data type

    float

    Measurement units
    • degree Celsius
    Alias
    UMLS CUI [1]
    C0039476
    degree Celsius
    Not taken
    Description

    Temperature not taken

    Data type

    boolean

    Alias
    UMLS CUI [1]
    C0039476
    Weekdays location
    Description

    Weekdays location

    Alias
    UMLS CUI-1
    C0450429
    UMLS CUI-2
    C0680189
    Daycare
    Description

    Record whereabouts of your child during daytime for 30 days prior to onset of varicella (chickenpox) rash or zoster case (shingles).

    Data type

    boolean

    Alias
    UMLS CUI [1]
    C0008070
    Daycare: Frequency: number of days?
    Description

    Record whereabouts of your child during daytime for 30 days prior to onset of varicella (chickenpox) rash or zoster case (shingles).

    Data type

    integer

    Alias
    UMLS CUI [1,1]
    C0008070
    UMLS CUI [1,2]
    C0439603
    Home
    Description

    Record whereabouts of your child during daytime for 30 days prior to onset of varicella (chickenpox) rash or zoster case (shingles).

    Data type

    boolean

    Alias
    UMLS CUI [1]
    C0442519
    Home: Frequency: number of days?
    Description

    Record whereabouts of your child during daytime for 30 days prior to onset of varicella (chickenpox) rash or zoster case (shingles).

    Data type

    integer

    Alias
    UMLS CUI [1,1]
    C0442519
    UMLS CUI [1,2]
    C0439603
    School
    Description

    Record whereabouts of your child during daytime for 30 days prior to onset of varicella (chickenpox) rash or zoster case (shingles).

    Data type

    boolean

    Alias
    UMLS CUI [1]
    C0036375
    School: Frequency: number of days?
    Description

    Record whereabouts of your child during daytime for 30 days prior to onset of varicella (chickenpox) rash or zoster case (shingles).

    Data type

    integer

    Alias
    UMLS CUI [1,1]
    C0036375
    UMLS CUI [1,2]
    C0439603
    Childminder
    Description

    Record whereabouts of your child during daytime for 30 days prior to onset of varicella (chickenpox) rash or zoster case (shingles).

    Data type

    boolean

    Alias
    UMLS CUI [1]
    C0730005
    Childminder: Frequency: number of days?
    Description

    Record whereabouts of your child during daytime for 30 days prior to onset of varicella (chickenpox) rash or zoster case (shingles).

    Data type

    integer

    Alias
    UMLS CUI [1,1]
    C0730005
    UMLS CUI [1,2]
    C0439603
    Number of children at childminder
    Description

    Number of children at childminder

    Data type

    integer

    Alias
    UMLS CUI [1,1]
    C0730005
    UMLS CUI [1,2]
    C0008059
    UMLS CUI [1,3]
    C0449788
    Number of children with negative varicella history?
    Description

    at childminder

    Data type

    integer

    Alias
    UMLS CUI [1,1]
    C0008059
    UMLS CUI [1,2]
    C0449788
    UMLS CUI [1,3]
    C0455469
    Number of children with negative varicella history unknown.
    Description

    Number of children with negative varicella history unknown

    Data type

    boolean

    Alias
    UMLS CUI [1,1]
    C0008059
    UMLS CUI [1,2]
    C0449788
    UMLS CUI [1,3]
    C0455469
    Other, specify:
    Description

    Record whereabouts of your child during daytime for 30 days prior to onset of varicella (chickenpox) rash or zoster case (shingles).

    Data type

    text

    Alias
    UMLS CUI [1,1]
    C0450429
    UMLS CUI [1,2]
    C0205394
    UMLS CUI [1,3]
    C1521902
    Other location
    Description

    Record whereabouts of your child during daytime for 30 days prior to onset of varicella (chickenpox) rash or zoster case (shingles).

    Data type

    boolean

    Alias
    UMLS CUI [1,1]
    C0450429
    UMLS CUI [1,2]
    C0205394
    Other location: Frequency: number of days?
    Description

    Record whereabouts of your child during daytime for 30 days prior to onset of varicella (chickenpox) rash or zoster case (shingles).

    Data type

    integer

    Alias
    UMLS CUI [1,1]
    C0450429
    UMLS CUI [1,2]
    C0205394
    UMLS CUI [1,3]
    C0439603
    Varicella or zoster index case
    Description

    Varicella or zoster index case

    Alias
    UMLS CUI-1
    C2597943
    UMLS CUI-2
    C0008049
    UMLS CUI-4
    C2597943
    UMLS CUI-5
    C0740380
    In last 30 days - prior to onset of varicella (chickenpox) or zoster case (shingles) - was there a recognized exposure of the subject with an index case, was there a recognized exposure of your child with index case?
    Description

    Varicella or zoster index case

    Data type

    boolean

    Alias
    UMLS CUI [1,1]
    C2597943
    UMLS CUI [1,2]
    C0008049
    UMLS CUI [2,1]
    C2597943
    UMLS CUI [2,2]
    C0740380
    Type of contact
    Description

    Type of contact

    Data type

    integer

    Alias
    UMLS CUI [1,1]
    C0332158
    UMLS CUI [1,2]
    C0332307
    Frequency
    Description

    Frequency of contact

    Data type

    integer

    Alias
    UMLS CUI [1,1]
    C0008049
    UMLS CUI [1,2]
    C0332158
    UMLS CUI [1,3]
    C0439603
    Date of contact
    Description

    Only answer if you choose "occasional contact"

    Data type

    date

    Alias
    UMLS CUI [1,1]
    C0011008
    UMLS CUI [1,2]
    C0332158
    UMLS CUI [1,3]
    C0008049
    Nature of contact
    Description

    Nature of contact

    Data type

    integer

    Alias
    UMLS CUI [1,1]
    C0392367
    UMLS CUI [1,2]
    C0332307
    Other: specify
    Description

    Specify other kind of contact

    Data type

    text

    Alias
    UMLS CUI [1,1]
    C0392367
    UMLS CUI [1,2]
    C0205394
    UMLS CUI [1,3]
    C1521902
    Date varicella or zoster end
    Description

    Date varicella or zoster end

    Alias
    UMLS CUI-1
    C0008049
    UMLS CUI-2
    C0806020
    UMLS CUI-4
    C0740380
    UMLS CUI-5
    C0806020
    Date end of varicella (chickenpox)/ zoster (shingles)
    Description

    date when subject resumes normal everyday activities.

    Data type

    date

    Alias
    UMLS CUI [1,1]
    C0008049
    UMLS CUI [1,2]
    C0806020
    UMLS CUI [2,1]
    C0740380
    UMLS CUI [2,2]
    C0806020
    Health economics
    Description

    Health economics

    Alias
    UMLS CUI-1
    C0013556
    UMLS CUI-2
    C0018684
    Did you, as parent/guardian, or your family members, lose time from work as a result of taking care of your child during this illness?
    Description

    work time lost due to care taking

    Data type

    boolean

    Alias
    UMLS CUI [1,1]
    C0237107
    UMLS CUI [1,2]
    C0012634
    UMLS CUI [1,3]
    C0585074
    How many hours?
    Description

    Only answer if you answered previous question with 'yes'. How many hours did the parents/guardians or family members lose time from work as a result of taking care of the subject during this illness ?

    Data type

    integer

    Alias
    UMLS CUI [1,1]
    C0439227
    UMLS CUI [1,2]
    C1265611
    UMLS CUI [1,3]
    C0030551
    Did your child lose any days in the day care / childminder / school attendance or any extra-curricular activities (e.g. sports or recreation or any type of organized leisure activities) during this illness?
    Description

    time lost at day care / childminder / school attendance / extracurricular activity

    Data type

    boolean

    Alias
    UMLS CUI [1,1]
    C2185951
    UMLS CUI [1,2]
    C0008070
    UMLS CUI [2,1]
    C2185951
    UMLS CUI [2,2]
    C0730005
    UMLS CUI [3,1]
    C2185951
    UMLS CUI [3,2]
    C0036375
    UMLS CUI [4,1]
    C2185951
    UMLS CUI [4,2]
    C0681383
    How many hours?
    Description

    Only answer if you answered previous question with 'yes'. How many hours did the subject lose in the day care / childminder / school attendance or at extra-curricular activities (e.g. sports or recreation or any type of organised leisure activities) during this illness?

    Data type

    integer

    Alias
    UMLS CUI [1,1]
    C0439227
    UMLS CUI [1,2]
    C1265611
    UMLS CUI [1,3]
    C0008059
    Did you request assistance from a nurse, a babysitter or any type of paid caregiver to look after your child during this illness?
    Description

    Assistance needed by nurse, babysitter or any type of paid caregiver

    Data type

    boolean

    Alias
    UMLS CUI [1,1]
    C3840284
    UMLS CUI [1,2]
    C0028661
    UMLS CUI [2,1]
    C3840284
    UMLS CUI [2,2]
    C0337606
    UMLS CUI [3,1]
    C3840284
    UMLS CUI [3,2]
    C0085537
    How many hours?
    Description

    How many hours did the parents / guardians request assistance from a nurse, a babysitter or any type of paid caregiver to look after the subject during this illness?

    Data type

    integer

    Alias
    UMLS CUI [1,1]
    C0439227
    UMLS CUI [1,2]
    C1265611
    UMLS CUI [1,3]
    C0085537
    If your child were not participating in this trial, would you, as parents / guardians, have contacted or visited a physician to seek medical advice for this illness?
    Description

    Parents seeking medical advice for illness

    Data type

    boolean

    Alias
    UMLS CUI [1,1]
    C1386497
    UMLS CUI [1,2]
    C0030551
    UMLS CUI [1,3]
    C2348568
    Pain
    Description

    Pain

    Alias
    UMLS CUI-1
    C0030193
    Did the child present any back or abdominal pain during this illness?
    Description

    back or abdominal pain varicella or zoster

    Data type

    boolean

    Alias
    UMLS CUI [1,1]
    C0004604
    UMLS CUI [1,2]
    C0008049
    UMLS CUI [1,3]
    C0740380
    UMLS CUI [2,1]
    C0000737
    UMLS CUI [2,2]
    C0008049
    UMLS CUI [2,3]
    C0740380
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    Diary Card - Varicella /Zoster Case - GSK Study: Evaluation of safety and efficacy of VarilrixTM and of Combined Measles-Mumps-Rubella-Varicella Vaccine NCT00226499

    1 forms
    Name
    Type
    Description | Question | Decode (Coded Value)
    Data type
    Alias
    Item Group
    Rash
    C0015230 (UMLS CUI-1)
    Date rash onset
    Item
    Date rash onset
    date
    C0015230 (UMLS CUI [1,1])
    C0574845 (UMLS CUI [1,2])
    Date rash end
    Item
    Date rash end
    date
    C0015230 (UMLS CUI [1,1])
    C0806020 (UMLS CUI [1,2])
    Item Group
    Lesion
    C0221198 (UMLS CUI-1)
    Day
    Item
    Day
    integer
    C0439228 (UMLS CUI [1,1])
    C0750480 (UMLS CUI [1,2])
    C0221198 (UMLS CUI [1,3])
    Item
    Daily number of overall Lesions
    integer
    C0221198 (UMLS CUI [1,1])
    C0449788 (UMLS CUI [1,2])
    C0332173 (UMLS CUI [1,3])
    Daily number of overall Lesions
    Code List
    Daily number of overall Lesions
    CL Item
    1-50 (1)
    CL Item
    51-100 (2)
    CL Item
    101-500 (3)
    CL Item
    >500 (4)
    Item Group
    Vesicles
    C0333262 (UMLS CUI-1)
    Day
    Item
    Day
    text
    C0439228 (UMLS CUI [1,1])
    C0750480 (UMLS CUI [1,2])
    C0333262 (UMLS CUI [1,3])
    Item
    Daily number of overall Vesicles
    integer
    C0333262 (UMLS CUI [1,1])
    C0449788 (UMLS CUI [1,2])
    C0332173 (UMLS CUI [1,3])
    undefined item
    Code List
    Daily number of overall Vesicles
    CL Item
    None (1)
    CL Item
    1-10 (2)
    CL Item
    11-50 (3)
    CL Item
    >50 (4)
    Item Group
    Temperature
    C0039476 (UMLS CUI-1)
    Item
    Route
    text
    C0005903 (UMLS CUI [1,1])
    C1515974 (UMLS CUI [1,2])
    Route body temperature
    Code List
    Route
    CL Item
    Axillary (A)
    CL Item
    Rectal (R)
    Item Group
    Temperature
    C0039476 (UMLS CUI-1)
    Day
    Item
    Day
    integer
    C0439228 (UMLS CUI [1,1])
    C0750480 (UMLS CUI [1,2])
    C0039476 (UMLS CUI [1,3])
    Date Temperature
    Item
    Date
    date
    C0039476 (UMLS CUI [1,1])
    C0011008 (UMLS CUI [1,2])
    Temperature
    Item
    Temperature
    float
    C0039476 (UMLS CUI [1])
    Temperature not taken
    Item
    Not taken
    boolean
    C0039476 (UMLS CUI [1])
    Item Group
    Weekdays location
    C0450429 (UMLS CUI-1)
    C0680189 (UMLS CUI-2)
    Daycare
    Item
    Daycare
    boolean
    C0008070 (UMLS CUI [1])
    Frequency of time spend in daycare
    Item
    Daycare: Frequency: number of days?
    integer
    C0008070 (UMLS CUI [1,1])
    C0439603 (UMLS CUI [1,2])
    Home
    Item
    Home
    boolean
    C0442519 (UMLS CUI [1])
    Frequency of time spend at home
    Item
    Home: Frequency: number of days?
    integer
    C0442519 (UMLS CUI [1,1])
    C0439603 (UMLS CUI [1,2])
    School
    Item
    School
    boolean
    C0036375 (UMLS CUI [1])
    Frequency of time spend at school
    Item
    School: Frequency: number of days?
    integer
    C0036375 (UMLS CUI [1,1])
    C0439603 (UMLS CUI [1,2])
    Childminder
    Item
    Childminder
    boolean
    C0730005 (UMLS CUI [1])
    Frequency of time spend at childminder
    Item
    Childminder: Frequency: number of days?
    integer
    C0730005 (UMLS CUI [1,1])
    C0439603 (UMLS CUI [1,2])
    Number of children at childminder
    Item
    Number of children at childminder
    integer
    C0730005 (UMLS CUI [1,1])
    C0008059 (UMLS CUI [1,2])
    C0449788 (UMLS CUI [1,3])
    Number of children with negative varicella history
    Item
    Number of children with negative varicella history?
    integer
    C0008059 (UMLS CUI [1,1])
    C0449788 (UMLS CUI [1,2])
    C0455469 (UMLS CUI [1,3])
    Number of children with negative varicella history unknown
    Item
    Number of children with negative varicella history unknown.
    boolean
    C0008059 (UMLS CUI [1,1])
    C0449788 (UMLS CUI [1,2])
    C0455469 (UMLS CUI [1,3])
    specify other location
    Item
    Other, specify:
    text
    C0450429 (UMLS CUI [1,1])
    C0205394 (UMLS CUI [1,2])
    C1521902 (UMLS CUI [1,3])
    Other location
    Item
    Other location
    boolean
    C0450429 (UMLS CUI [1,1])
    C0205394 (UMLS CUI [1,2])
    Frequency of time spend at other location
    Item
    Other location: Frequency: number of days?
    integer
    C0450429 (UMLS CUI [1,1])
    C0205394 (UMLS CUI [1,2])
    C0439603 (UMLS CUI [1,3])
    Item Group
    Varicella or zoster index case
    C2597943 (UMLS CUI-1)
    C0008049 (UMLS CUI-2)
    C2597943 (UMLS CUI-4)
    C0740380 (UMLS CUI-5)
    Varicella or zoster index case
    Item
    In last 30 days - prior to onset of varicella (chickenpox) or zoster case (shingles) - was there a recognized exposure of the subject with an index case, was there a recognized exposure of your child with index case?
    boolean
    C2597943 (UMLS CUI [1,1])
    C0008049 (UMLS CUI [1,2])
    C2597943 (UMLS CUI [2,1])
    C0740380 (UMLS CUI [2,2])
    Item
    Type of contact
    integer
    C0332158 (UMLS CUI [1,1])
    C0332307 (UMLS CUI [1,2])
    Type of contact
    Code List
    Type of contact
    CL Item
    Varicella (1)
    CL Item
    Zoster (2)
    Item
    Frequency
    integer
    C0008049 (UMLS CUI [1,1])
    C0332158 (UMLS CUI [1,2])
    C0439603 (UMLS CUI [1,3])
    Frequency of contact
    Code List
    Frequency
    CL Item
    Occasional contact (1)
    CL Item
    Daily contact (2)
    Date of contact
    Item
    Date of contact
    date
    C0011008 (UMLS CUI [1,1])
    C0332158 (UMLS CUI [1,2])
    C0008049 (UMLS CUI [1,3])
    Item
    Nature of contact
    integer
    C0392367 (UMLS CUI [1,1])
    C0332307 (UMLS CUI [1,2])
    Nature of contact
    Code List
    Nature of contact
    CL Item
    Household (1)
    CL Item
    Daycare center (2)
    CL Item
    Childminder (3)
    CL Item
    Playmate (4)
    CL Item
    School (in the same building) (5)
    CL Item
    School (in a different building) (6)
    CL Item
    Classroom (7)
    CL Item
    Other: specify (8)
    Specify other kind of contact
    Item
    Other: specify
    text
    C0392367 (UMLS CUI [1,1])
    C0205394 (UMLS CUI [1,2])
    C1521902 (UMLS CUI [1,3])
    Item Group
    Date varicella or zoster end
    C0008049 (UMLS CUI-1)
    C0806020 (UMLS CUI-2)
    C0740380 (UMLS CUI-4)
    C0806020 (UMLS CUI-5)
    End Date Varicella or zoster
    Item
    Date end of varicella (chickenpox)/ zoster (shingles)
    date
    C0008049 (UMLS CUI [1,1])
    C0806020 (UMLS CUI [1,2])
    C0740380 (UMLS CUI [2,1])
    C0806020 (UMLS CUI [2,2])
    Item Group
    Health economics
    C0013556 (UMLS CUI-1)
    C0018684 (UMLS CUI-2)
    work time lost due to care taking
    Item
    Did you, as parent/guardian, or your family members, lose time from work as a result of taking care of your child during this illness?
    boolean
    C0237107 (UMLS CUI [1,1])
    C0012634 (UMLS CUI [1,2])
    C0585074 (UMLS CUI [1,3])
    Amount of hours
    Item
    How many hours?
    integer
    C0439227 (UMLS CUI [1,1])
    C1265611 (UMLS CUI [1,2])
    C0030551 (UMLS CUI [1,3])
    time lost at day care / childminder / school attendance / extracurricular activity
    Item
    Did your child lose any days in the day care / childminder / school attendance or any extra-curricular activities (e.g. sports or recreation or any type of organized leisure activities) during this illness?
    boolean
    C2185951 (UMLS CUI [1,1])
    C0008070 (UMLS CUI [1,2])
    C2185951 (UMLS CUI [2,1])
    C0730005 (UMLS CUI [2,2])
    C2185951 (UMLS CUI [3,1])
    C0036375 (UMLS CUI [3,2])
    C2185951 (UMLS CUI [4,1])
    C0681383 (UMLS CUI [4,2])
    Amount of hours
    Item
    How many hours?
    integer
    C0439227 (UMLS CUI [1,1])
    C1265611 (UMLS CUI [1,2])
    C0008059 (UMLS CUI [1,3])
    Assistance needed by nurse, babysitter or any type of paid caregiver
    Item
    Did you request assistance from a nurse, a babysitter or any type of paid caregiver to look after your child during this illness?
    boolean
    C3840284 (UMLS CUI [1,1])
    C0028661 (UMLS CUI [1,2])
    C3840284 (UMLS CUI [2,1])
    C0337606 (UMLS CUI [2,2])
    C3840284 (UMLS CUI [3,1])
    C0085537 (UMLS CUI [3,2])
    Amount of hours
    Item
    How many hours?
    integer
    C0439227 (UMLS CUI [1,1])
    C1265611 (UMLS CUI [1,2])
    C0085537 (UMLS CUI [1,3])
    Parents seeking medical advice for illness
    Item
    If your child were not participating in this trial, would you, as parents / guardians, have contacted or visited a physician to seek medical advice for this illness?
    boolean
    C1386497 (UMLS CUI [1,1])
    C0030551 (UMLS CUI [1,2])
    C2348568 (UMLS CUI [1,3])
    Item Group
    Pain
    C0030193 (UMLS CUI-1)
    back or abdominal pain varicella or zoster
    Item
    Did the child present any back or abdominal pain during this illness?
    boolean
    C0004604 (UMLS CUI [1,1])
    C0008049 (UMLS CUI [1,2])
    C0740380 (UMLS CUI [1,3])
    C0000737 (UMLS CUI [2,1])
    C0008049 (UMLS CUI [2,2])
    C0740380 (UMLS CUI [2,3])
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