ID

22141

Descripción

Gene Expression Profiles in Multiple Sclerosis (MS); ODM derived from: https://clinicaltrials.gov/show/NCT00704834

Link

https://clinicaltrials.gov/show/NCT00704834

Palabras clave

  1. 21/5/17 21/5/17 -
Subido en

21 de mayo de 2017

DOI

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Licencia

Creative Commons BY 4.0

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Eligibility Multiple Sclerosis NCT00704834

Eligibility Multiple Sclerosis NCT00704834

Inclusion Criteria
Descripción

Inclusion Criteria

Alias
UMLS CUI
C1512693
males and females
Descripción

gender

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0079399
any race
Descripción

race

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0034510
between the ages of 18 and 70 years
Descripción

age

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0001779
diagnosed with a clinically isolated syndrome or the diagnosis of multiple sclerosis using the widely established macdonald criteria.
Descripción

multiple sclerosis macdonald criteria

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0026769
UMLS CUI [1,2]
C2921627
UMLS CUI [1,3]
C0243161
a 'clinically isolated syndrome' refers to an isolated attack of optic neuritis, transverse myelitis, or brain demyelination. relapsing-remitting ms is characterized by acute relapses that are followed by some degree of recovery without worsening of disability between relapses. chronic progressive ms is defined as sustained progression of physical disability, occurring separately from relapses, in patients with ms.
Descripción

multiple sclerosis

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0026769
control subjects will be male or female, between the ages 18 to 70 years, of any race, with no symptoms of ms.
Descripción

control subjects

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0009932
Exclusion Criteria
Descripción

Exclusion Criteria

Alias
UMLS CUI
C0680251
children are excluded from the study because ms is generally a disease of young adult onset and is rare in children.
Descripción

children

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0008059
evidence of infection or communicable disease, cancer or other known systemic disease, anti-coagulation, known bleeding disorder, illicit drug abuse, or change in medications in the last 30 days (including treatment with steroids).
Descripción

infection, cancer, systemic disease, anticoagulation, bleeding disorder, drug abuse, medication change

Tipo de datos

boolean

Alias
UMLS CUI [1]
C0009450
UMLS CUI [2]
C0006826
UMLS CUI [3]
C0442893
UMLS CUI [4]
C0003281
UMLS CUI [5]
C0005779
UMLS CUI [6]
C0013146
UMLS CUI [7]
C0580105
patients receiving any other immune modulating medications (steroids, cyclophosphamide, mitoxantrone, methotrexate, mycophenolate mofetil, azathioprine, ivig or rituximab) in the prior thirty days will be excluded from the study
Descripción

immune modulating medications

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0013227
UMLS CUI [1,2]
C0678889

Similar models

Eligibility Multiple Sclerosis NCT00704834

Name
Tipo
Description | Question | Decode (Coded Value)
Tipo de datos
Alias
Item Group
C1512693 (UMLS CUI)
gender
Item
males and females
boolean
C0079399 (UMLS CUI [1])
race
Item
any race
boolean
C0034510 (UMLS CUI [1])
age
Item
between the ages of 18 and 70 years
boolean
C0001779 (UMLS CUI [1])
multiple sclerosis macdonald criteria
Item
diagnosed with a clinically isolated syndrome or the diagnosis of multiple sclerosis using the widely established macdonald criteria.
boolean
C0026769 (UMLS CUI [1,1])
C2921627 (UMLS CUI [1,2])
C0243161 (UMLS CUI [1,3])
multiple sclerosis
Item
a 'clinically isolated syndrome' refers to an isolated attack of optic neuritis, transverse myelitis, or brain demyelination. relapsing-remitting ms is characterized by acute relapses that are followed by some degree of recovery without worsening of disability between relapses. chronic progressive ms is defined as sustained progression of physical disability, occurring separately from relapses, in patients with ms.
boolean
C0026769 (UMLS CUI [1])
control subjects
Item
control subjects will be male or female, between the ages 18 to 70 years, of any race, with no symptoms of ms.
boolean
C0009932 (UMLS CUI [1])
Item Group
C0680251 (UMLS CUI)
children
Item
children are excluded from the study because ms is generally a disease of young adult onset and is rare in children.
boolean
C0008059 (UMLS CUI [1])
infection, cancer, systemic disease, anticoagulation, bleeding disorder, drug abuse, medication change
Item
evidence of infection or communicable disease, cancer or other known systemic disease, anti-coagulation, known bleeding disorder, illicit drug abuse, or change in medications in the last 30 days (including treatment with steroids).
boolean
C0009450 (UMLS CUI [1])
C0006826 (UMLS CUI [2])
C0442893 (UMLS CUI [3])
C0003281 (UMLS CUI [4])
C0005779 (UMLS CUI [5])
C0013146 (UMLS CUI [6])
C0580105 (UMLS CUI [7])
immune modulating medications
Item
patients receiving any other immune modulating medications (steroids, cyclophosphamide, mitoxantrone, methotrexate, mycophenolate mofetil, azathioprine, ivig or rituximab) in the prior thirty days will be excluded from the study
boolean
C0013227 (UMLS CUI [1,1])
C0678889 (UMLS CUI [1,2])

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