ID

21774

Beskrivning

Treatment-Resistant Depression, Hippocampus Atrophy and Serotonin Genetic Polymorphism; ODM derived from: https://clinicaltrials.gov/show/NCT00704860

Länk

https://clinicaltrials.gov/show/NCT00704860

Nyckelord

  1. 2017-04-29 2017-04-29 -
Uppladdad den

29 april 2017

DOI

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Licens

Creative Commons BY 4.0

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Eligibility Major Depression NCT00704860

Eligibility Major Depression NCT00704860

Inclusion Criteria
Beskrivning

Inclusion Criteria

Alias
UMLS CUI
C1512693
male or female between ages of 18 to 65 years of age.
Beskrivning

Age

Datatyp

boolean

Alias
UMLS CUI [1]
C0001779
a diagnosis of major depression according to the dsm-iv criteria
Beskrivning

Major Depressive Disorder

Datatyp

boolean

Alias
UMLS CUI [1]
C1269683
failing to achieve remission while receiving at least two different antidepressants at adequate dosage for at least 6 weeks.
Beskrivning

Antidepressive Agents Different Quantity Dosage | Disease remission failed

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0003289
UMLS CUI [1,2]
C1705242
UMLS CUI [1,3]
C1265611
UMLS CUI [1,4]
C0178602
UMLS CUI [2,1]
C0544452
UMLS CUI [2,2]
C0231175
initial score of at least 18 on the hamd-17 item rating scale
Beskrivning

Hamilton Depression Rating Scale 17 Item Questionnaire

Datatyp

boolean

Alias
UMLS CUI [1]
C3639712
Exclusion Criteria
Beskrivning

Exclusion Criteria

Alias
UMLS CUI
C0680251
a diagnosis of substance abuse or dependence in the last 6 months or a lifetime diagnosis of substance abuse according to the dsm-iv criteria, elicited by inquiry.
Beskrivning

Substance Use Disorders | Substance Dependence | Substance Use Disorders Lifetime

Datatyp

boolean

Alias
UMLS CUI [1]
C0038586
UMLS CUI [2]
C0038580
UMLS CUI [3,1]
C0038586
UMLS CUI [3,2]
C4071830
a diagnosis of post-traumatic stress disorder, schizophrenia, schizo-affective disorder and other psychotic disorders, anorexia nervosa or a history of a manic or mixed episode
Beskrivning

Post-Traumatic Stress Disorder | Schizophrenia | Schizoaffective Disorder | Psychotic Disorders | Anorexia Nervosa | Manic episode | Mixed manic depressive episode

Datatyp

boolean

Alias
UMLS CUI [1]
C0038436
UMLS CUI [2]
C0036341
UMLS CUI [3]
C0036337
UMLS CUI [4]
C0033975
UMLS CUI [5]
C0003125
UMLS CUI [6]
C0349208
UMLS CUI [7]
C1608433
major medical illnesses including endocrine and neurological disorders, as well as a history of significant head trauma
Beskrivning

Illnes Major | Endocrine System Diseases | nervous system disorder | Craniocerebral Trauma

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0221423
UMLS CUI [1,2]
C0205164
UMLS CUI [2]
C0014130
UMLS CUI [3]
C0027765
UMLS CUI [4]
C0018674
exposure to oral or intravenous steroids
Beskrivning

Oral steroids Exposure to | Intravenous steroids Exposure to

Datatyp

boolean

Alias
UMLS CUI [1,1]
C0038317
UMLS CUI [1,2]
C1527415
UMLS CUI [1,3]
C0332157
UMLS CUI [2,1]
C0563322
UMLS CUI [2,2]
C0332157
contraindications to magnetic resonance imaging
Beskrivning

Medical contraindication Magnetic Resonance Imaging

Datatyp

boolean

Alias
UMLS CUI [1,1]
C1301624
UMLS CUI [1,2]
C0024485
an iq less than 80
Beskrivning

Intelligence quotient

Datatyp

boolean

Alias
UMLS CUI [1]
C0456149

Similar models

Eligibility Major Depression NCT00704860

Name
Typ
Description | Question | Decode (Coded Value)
Datatyp
Alias
Item Group
C1512693 (UMLS CUI)
Age
Item
male or female between ages of 18 to 65 years of age.
boolean
C0001779 (UMLS CUI [1])
Major Depressive Disorder
Item
a diagnosis of major depression according to the dsm-iv criteria
boolean
C1269683 (UMLS CUI [1])
Antidepressive Agents Different Quantity Dosage | Disease remission failed
Item
failing to achieve remission while receiving at least two different antidepressants at adequate dosage for at least 6 weeks.
boolean
C0003289 (UMLS CUI [1,1])
C1705242 (UMLS CUI [1,2])
C1265611 (UMLS CUI [1,3])
C0178602 (UMLS CUI [1,4])
C0544452 (UMLS CUI [2,1])
C0231175 (UMLS CUI [2,2])
Hamilton Depression Rating Scale 17 Item Questionnaire
Item
initial score of at least 18 on the hamd-17 item rating scale
boolean
C3639712 (UMLS CUI [1])
Item Group
C0680251 (UMLS CUI)
Substance Use Disorders | Substance Dependence | Substance Use Disorders Lifetime
Item
a diagnosis of substance abuse or dependence in the last 6 months or a lifetime diagnosis of substance abuse according to the dsm-iv criteria, elicited by inquiry.
boolean
C0038586 (UMLS CUI [1])
C0038580 (UMLS CUI [2])
C0038586 (UMLS CUI [3,1])
C4071830 (UMLS CUI [3,2])
Post-Traumatic Stress Disorder | Schizophrenia | Schizoaffective Disorder | Psychotic Disorders | Anorexia Nervosa | Manic episode | Mixed manic depressive episode
Item
a diagnosis of post-traumatic stress disorder, schizophrenia, schizo-affective disorder and other psychotic disorders, anorexia nervosa or a history of a manic or mixed episode
boolean
C0038436 (UMLS CUI [1])
C0036341 (UMLS CUI [2])
C0036337 (UMLS CUI [3])
C0033975 (UMLS CUI [4])
C0003125 (UMLS CUI [5])
C0349208 (UMLS CUI [6])
C1608433 (UMLS CUI [7])
Illnes Major | Endocrine System Diseases | nervous system disorder | Craniocerebral Trauma
Item
major medical illnesses including endocrine and neurological disorders, as well as a history of significant head trauma
boolean
C0221423 (UMLS CUI [1,1])
C0205164 (UMLS CUI [1,2])
C0014130 (UMLS CUI [2])
C0027765 (UMLS CUI [3])
C0018674 (UMLS CUI [4])
Oral steroids Exposure to | Intravenous steroids Exposure to
Item
exposure to oral or intravenous steroids
boolean
C0038317 (UMLS CUI [1,1])
C1527415 (UMLS CUI [1,2])
C0332157 (UMLS CUI [1,3])
C0563322 (UMLS CUI [2,1])
C0332157 (UMLS CUI [2,2])
Medical contraindication Magnetic Resonance Imaging
Item
contraindications to magnetic resonance imaging
boolean
C1301624 (UMLS CUI [1,1])
C0024485 (UMLS CUI [1,2])
Intelligence quotient
Item
an iq less than 80
boolean
C0456149 (UMLS CUI [1])

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