ID

20286

Descrizione

Transcranial Magnetic Stimulation in Parkinson's Disease; ODM derived from: https://clinicaltrials.gov/show/NCT00023062

collegamento

https://clinicaltrials.gov/show/NCT00023062

Keywords

versioni (1)
  1. 19/02/17 19/02/17 -
Caricato su

19 febbraio 2017

DOI

Per favore, per richiedere un accesso.

Licenza

Creative Commons BY 4.0
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Eligibility Parkinson Disease NCT00023062

Inglese

Eligibility Parkinson Disease NCT00023062

1 moduli  
Inclusion Criteria
Descrizione

Inclusion Criteria

Alias
UMLS CUI
C1512693
patients:
Descrizione

ID.1

Tipo di dati

boolean

patients with established, dopa-responsive pd, hoehn and yahr stage i-iii, age 21 and older will be included.
Descrizione

dopa-responsive parkinson

Tipo di dati

boolean

Alias
UMLS CUI [1]
C4012421
UMLS CUI [2]
C3639483
UMLS CUI [3]
C0001779
patients will be recruited from the ninds hmcs and etb clinical programs and from the community.
Descrizione

ID.3

Tipo di dati

boolean

healthy controls:
Descrizione

ID.4

Tipo di dati

boolean

healthy controls 21 and older will be recruited through the nih clinical research volunteer program and from the community.
Descrizione

age

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0001779
Exclusion Criteria
Descrizione

Exclusion Criteria

Alias
UMLS CUI
C0680251
exclusionary criteria will be: any significant medical or psychiatric illness (other than pd), pregnancy, history of epilepsy, concurrent use of tricyclic antidepressants, neuroleptic agents, or any other licit or illicit drugs that could lower the seizure threshold or significantly affect cortical excitability.
Descrizione

ID.6

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0221423
UMLS CUI [2]
C0032961
UMLS CUI [3]
C0014544
UMLS CUI [4,1]
C2347852
UMLS CUI [4,2]
C0003290
UMLS CUI [5,1]
C2347852
UMLS CUI [5,2]
C0040615
persons with surgically or traumatically implanted foreign bodies in the head (other than dental appliances of fillings) that may pose a physical hazard during magnetic stimulation will also be excluded.
Descrizione

foreign bodies in the head

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0016542
UMLS CUI [1,2]
C0018670
patients:
Descrizione

ID.8

Tipo di dati

boolean

patients with persistent "resting" tremor that precludes testing at rest may be excluded as well as any patient to whom the screening physician makes a judgment that withdrawal of medications poses a significant risk due to immobility or risk of falling.
Descrizione

persistent tremor

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0234370
patients on long-acting dopamine agonists will also be excluded.
Descrizione

long-acting dopamine agonists

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0178601
patients in hoehn and yahr stage iv will also be excluded, since they are least likely to tolerate medication withdrawal and are also unlikely to be able to maintain muscle relaxation for tms testing.
Descrizione

hoehn and yahr stage iv

Tipo di dati

boolean

Alias
UMLS CUI [1]
C3639483
no significant medical or psychiatric illness (other than pd), pregnancy, history of epilepsy, concurrent use of tricyclic antidepressants, neuroleptic agents, or any other licit or illicit drugs that could lower the seizure threshold or significantly affect cortical excitability.
Descrizione

no significant medical or psychiatric illness

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0221423
UMLS CUI [2]
C0032961
UMLS CUI [3]
C0014544
UMLS CUI [4,1]
C2347852
UMLS CUI [4,2]
C0003290
UMLS CUI [5,1]
C2347852
UMLS CUI [5,2]
C0040615
must not have surgically or traumatically implanted foreign bodies in the head (other than dental appliances or fillings) that may pose a physical hazard during magnetic stimulation.
Descrizione

foreign bodies in the head

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0016542
UMLS CUI [1,2]
C0018670
healthy controls:
Descrizione

ID.14

Tipo di dati

boolean

ages 21 and older will be recruited through the nih clinical research volunteer program (crvp) and from the community.
Descrizione

age

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0001779
all individuals will be processed through the crvp before participating. recruitment will be focused on optimizing age, sex, educational, and racial matching with patient group. patients' spouses will be invited to participate.
Descrizione

ID.16

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0679646
no significant medical or psychiatric illness (other than pd), pregnancy, history of epilepsy, concurrent use of tricyclic antidepressants, neuroleptic agents, or any other licit or illicit drugs that could lower the seizure threshold or significantly affect cortical excitability.
Descrizione

no significant medical or psychiatric illness

Tipo di dati

boolean

Alias
UMLS CUI [1]
C0221423
UMLS CUI [2]
C0032961
UMLS CUI [3]
C0014544
UMLS CUI [4,1]
C2347852
UMLS CUI [4,2]
C0003290
UMLS CUI [5,1]
C2347852
UMLS CUI [5,2]
C0040615
must not have surgically or traumatically implanted foreign bodies in the head (other than dental appliances or fillings) that may pose a physical hazard during magnetic stimulation.
Descrizione

foreign bodies in the head

Tipo di dati

boolean

Alias
UMLS CUI [1,1]
C0016542
UMLS CUI [1,2]
C0018670
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Similar models

Eligibility Parkinson Disease NCT00023062

1 moduli
Name
genere
Description | Question | Decode (Coded Value)
Tipo di dati
Alias
Item Group
C1512693 (UMLS CUI)
ID.1
Item
patients:
boolean
dopa-responsive parkinson
Item
patients with established, dopa-responsive pd, hoehn and yahr stage i-iii, age 21 and older will be included.
boolean
C4012421 (UMLS CUI [1])
C3639483 (UMLS CUI [2])
C0001779 (UMLS CUI [3])
ID.3
Item
patients will be recruited from the ninds hmcs and etb clinical programs and from the community.
boolean
ID.4
Item
healthy controls:
boolean
age
Item
healthy controls 21 and older will be recruited through the nih clinical research volunteer program and from the community.
boolean
C0001779 (UMLS CUI [1])
Item Group
C0680251 (UMLS CUI)
ID.6
Item
exclusionary criteria will be: any significant medical or psychiatric illness (other than pd), pregnancy, history of epilepsy, concurrent use of tricyclic antidepressants, neuroleptic agents, or any other licit or illicit drugs that could lower the seizure threshold or significantly affect cortical excitability.
boolean
C0221423 (UMLS CUI [1])
C0032961 (UMLS CUI [2])
C0014544 (UMLS CUI [3])
C2347852 (UMLS CUI [4,1])
C0003290 (UMLS CUI [4,2])
C2347852 (UMLS CUI [5,1])
C0040615 (UMLS CUI [5,2])
foreign bodies in the head
Item
persons with surgically or traumatically implanted foreign bodies in the head (other than dental appliances of fillings) that may pose a physical hazard during magnetic stimulation will also be excluded.
boolean
C0016542 (UMLS CUI [1,1])
C0018670 (UMLS CUI [1,2])
ID.8
Item
patients:
boolean
persistent tremor
Item
patients with persistent "resting" tremor that precludes testing at rest may be excluded as well as any patient to whom the screening physician makes a judgment that withdrawal of medications poses a significant risk due to immobility or risk of falling.
boolean
C0234370 (UMLS CUI [1])
long-acting dopamine agonists
Item
patients on long-acting dopamine agonists will also be excluded.
boolean
C0178601 (UMLS CUI [1])
hoehn and yahr stage iv
Item
patients in hoehn and yahr stage iv will also be excluded, since they are least likely to tolerate medication withdrawal and are also unlikely to be able to maintain muscle relaxation for tms testing.
boolean
C3639483 (UMLS CUI [1])
no significant medical or psychiatric illness
Item
no significant medical or psychiatric illness (other than pd), pregnancy, history of epilepsy, concurrent use of tricyclic antidepressants, neuroleptic agents, or any other licit or illicit drugs that could lower the seizure threshold or significantly affect cortical excitability.
boolean
C0221423 (UMLS CUI [1])
C0032961 (UMLS CUI [2])
C0014544 (UMLS CUI [3])
C2347852 (UMLS CUI [4,1])
C0003290 (UMLS CUI [4,2])
C2347852 (UMLS CUI [5,1])
C0040615 (UMLS CUI [5,2])
foreign bodies in the head
Item
must not have surgically or traumatically implanted foreign bodies in the head (other than dental appliances or fillings) that may pose a physical hazard during magnetic stimulation.
boolean
C0016542 (UMLS CUI [1,1])
C0018670 (UMLS CUI [1,2])
ID.14
Item
healthy controls:
boolean
age
Item
ages 21 and older will be recruited through the nih clinical research volunteer program (crvp) and from the community.
boolean
C0001779 (UMLS CUI [1])
ID.16
Item
all individuals will be processed through the crvp before participating. recruitment will be focused on optimizing age, sex, educational, and racial matching with patient group. patients' spouses will be invited to participate.
boolean
C0679646 (UMLS CUI [1])
no significant medical or psychiatric illness
Item
no significant medical or psychiatric illness (other than pd), pregnancy, history of epilepsy, concurrent use of tricyclic antidepressants, neuroleptic agents, or any other licit or illicit drugs that could lower the seizure threshold or significantly affect cortical excitability.
boolean
C0221423 (UMLS CUI [1])
C0032961 (UMLS CUI [2])
C0014544 (UMLS CUI [3])
C2347852 (UMLS CUI [4,1])
C0003290 (UMLS CUI [4,2])
C2347852 (UMLS CUI [5,1])
C0040615 (UMLS CUI [5,2])
foreign bodies in the head
Item
must not have surgically or traumatically implanted foreign bodies in the head (other than dental appliances or fillings) that may pose a physical hazard during magnetic stimulation.
boolean
C0016542 (UMLS CUI [1,1])
C0018670 (UMLS CUI [1,2])
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