Eligibility Schizophrenia NCT02435836

1. complete a prior study: each patient must meet one of the following conditions for completion of the prior study: a patient who has completed 52 weeks of post-randomization treatment in the prior double blind study (31-97-301 or 31-98-304-01) is eligible, with no further qualifications. a patient who was early-terminated from the study 31-97-301 or 31-98- 304-01 for either of the following two reasons is eligible to enter this open label study with no minimal required duration of prior double-blind participation: early termination was due to a marked deterioration of clinical status and no serious adverse events (sae) other than hospitalization has occurred. the marked clinical deterioration must be documented by at least a one-point increase in cgi-severity score from the baseline and a score of 6 (much worse) or 7 (very much worse) in cgi-global improvement at the time of termination, or early termination was due to a non-serious ae requiring discontinuation of the study drug a patient who was early terminated after a minimum of 4 weeks' participation in the double-blind treatment in study 31-97-301 or 31-98- 304-01 and the reason for early termination was withdrawal of consent due to lack of effect but not marked deterioration. this must be documented by no change from baseline in the cgi-severity score and a score of 4 (no change) or 5 (minimally worse) on the cgi-global improvement scale.

2. signing of informed consent form: prior to any procedure or drug administration, each patient must sign an informed consent form. in addition, if required by the ethical committee, each patient's next-of-kin or responsible caregiver will co-sign the patient's consent form or a separate consent form.

1. patients suffering from any significant somatic disease or medical problem that would obscure the results of treatment, or that might require frequent changes of concomitant medication.

2. patients with any acute or unstable medical condition requiring pharmacotherapy, other than schizophrenia.

3. patients with an abnormal laboratory test value in the most recent analysis (from the study 31-97-301 or 31-98-304-01) which is considered by the investigator as presenting a significant risk to the patient for continuing treatment with aripiprazole.

4. patients who were early-terminated from the prior double-blind studies (31-97-301 or 31-98-304-01) due to a serious adverse event (sae) other than worsening of psychosis or hospitalization.

5. female patients of child bearing potential with a positive serum pregnancy test at the baseline (last visit of prior study) of this open-label follow-on study.

6. patients who have positive result in the urine screen for drugs of abuse (except for cannabis or medically-prescribed analgesics or benzodiazepines.)