ID

13078

Beschrijving

Randomized Study of Fetal Neurotransplantation for the Treatment of Parkinson's Disease; ODM derived from: https://clinicaltrials.gov/show/NCT00004844

Link

https://clinicaltrials.gov/show/NCT00004844

Trefwoorden

  1. 15-01-16 15-01-16 -
Houder van rechten

CC BY-NC 3.0

Geüploaded op

15 januari 2016

DOI

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Licentie

Creative Commons BY-NC 3.0

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Eligibility Parkinson Disease NCT00004844

Eligibility Parkinson Disease NCT00004844

Criteria
Beschrijving

Criteria

idiopathic parkinson's disease for at least 7 years with rest tremor or bradykinesia and one of the following cardinal signs: rigidity flexed posture loss of postural reflexes freezing (motor blocks)
Beschrijving

parkinson's disease

Datatype

boolean

Alias
UMLS CUI [1]
C0030567
continuing response to levodopa
Beschrijving

levodopa

Datatype

boolean

Alias
UMLS CUI [1]
C0023570
presence of at least one of the following intractable symptoms or signs: intractable disabling fluctuations intractable disabling dyskinesias intractable "on" freezing (i.e., motor blocks that interfere with walking despite being "on"
Beschrijving

intractable symptoms

Datatype

boolean

Alias
UMLS CUI [1]
C0205269
bilateral parkinsonism when "off" (may be asymmetry between right and left sides)
Beschrijving

bilateral parkinsonism

Datatype

boolean

decreased dopa uptake in the striatum
Beschrijving

dopa uptake

Datatype

boolean

Alias
UMLS CUI [1]
C0013023
no prior brain surgery
Beschrijving

brain surgery

Datatype

boolean

Alias
UMLS CUI [1]
C0195775
cardiovascular: no severe cardiopulmonary disease
Beschrijving

cardiopulmonary disease

Datatype

boolean

Alias
UMLS CUI [1]
C0009488
neurologic: no history of strokes no neuroleptics no encephalitis no oculogyric crisis no remission no cerebellar signs no dementia (mini-mental state score no greater than 22) no supranuclear gaze palsy no babinski sign no orthostatic hypotension no hydrocephalus no brain tumor no occlusive cerebrovascular disease
Beschrijving

neurologic disorder

Datatype

boolean

Alias
UMLS CUI [1]
C0027765
pulmonary: absolute standing pressure at least 90/60 mmhg
Beschrijving

pulmonary pressure

Datatype

boolean

Alias
UMLS CUI [1]
C0428642
other: no diabetes mellitus no exposure to toxins no other severe medical disease hamilton depression scale score of less than 20 points
Beschrijving

comorbidity

Datatype

boolean

Alias
UMLS CUI [1]
C0009488

Similar models

Eligibility Parkinson Disease NCT00004844

Name
Type
Description | Question | Decode (Coded Value)
Datatype
Alias
Item Group
parkinson's disease
Item
idiopathic parkinson's disease for at least 7 years with rest tremor or bradykinesia and one of the following cardinal signs: rigidity flexed posture loss of postural reflexes freezing (motor blocks)
boolean
C0030567 (UMLS CUI [1])
levodopa
Item
continuing response to levodopa
boolean
C0023570 (UMLS CUI [1])
intractable symptoms
Item
presence of at least one of the following intractable symptoms or signs: intractable disabling fluctuations intractable disabling dyskinesias intractable "on" freezing (i.e., motor blocks that interfere with walking despite being "on"
boolean
C0205269 (UMLS CUI [1])
bilateral parkinsonism
Item
bilateral parkinsonism when "off" (may be asymmetry between right and left sides)
boolean
dopa uptake
Item
decreased dopa uptake in the striatum
boolean
C0013023 (UMLS CUI [1])
brain surgery
Item
no prior brain surgery
boolean
C0195775 (UMLS CUI [1])
cardiopulmonary disease
Item
cardiovascular: no severe cardiopulmonary disease
boolean
C0009488 (UMLS CUI [1])
neurologic disorder
Item
neurologic: no history of strokes no neuroleptics no encephalitis no oculogyric crisis no remission no cerebellar signs no dementia (mini-mental state score no greater than 22) no supranuclear gaze palsy no babinski sign no orthostatic hypotension no hydrocephalus no brain tumor no occlusive cerebrovascular disease
boolean
C0027765 (UMLS CUI [1])
pulmonary pressure
Item
pulmonary: absolute standing pressure at least 90/60 mmhg
boolean
C0428642 (UMLS CUI [1])
comorbidity
Item
other: no diabetes mellitus no exposure to toxins no other severe medical disease hamilton depression scale score of less than 20 points
boolean
C0009488 (UMLS CUI [1])

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