ID

12883

Descripción

Documentation part: Table V (Recommendations for supplemental asthma outcomes for NIH- initiated clinical research for children). ODM derived from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259286/ Background: Asthma clinical research will highly benefit from standardization of major outcomes in terms of definition and assessment methodology. This will permit useful comparisons across interventional or observational studies and will allow more effective data sharing. Objective: National Institutes of Health (NIH) institutes and the Agency for Healthcare Research and Quality (AHRQ) convened a workshop involving 7 expert subcommittees to propose which asthma outcomes should be assessed with standardized methodology in future asthma clinical research studies. Permission granted by: Michelle Freemer.

Link

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259286/

Palabras clave

  1. 5/1/16 5/1/16 -
  2. 23/2/16 23/2/16 -
  3. 24/2/16 24/2/16 - Julian Varghese
Subido en

5 de enero de 2016

DOI

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Licencia

Creative Commons BY-NC 3.0

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Table V- Supplemental Asthma Outcomes NIH AHRQ for children

Table V- Supplemental Asthma Outcomes NIH AHRQ for children

Characterization of study population for prospective clinical trials
Descripción

Characterization of study population for prospective clinical trials

Alias
UMLS CUI-1
C2348561
UMLS CUI-2
C1880022
UMLS CUI-4
C0008976
Biomarkers
Descripción

Biomarkers

Tipo de datos

text

Alias
UMLS CUI [1]
C0005516
Exacerbation of asthma
Descripción

Exacerbation of asthma

Tipo de datos

text

Alias
UMLS CUI [1]
C0349790
Healthcare Utilization and Costs
Descripción

Utilization healthcare; Costs healthcare

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0042153
UMLS CUI [1,2]
C0086388
UMLS CUI [2,1]
C0010186
UMLS CUI [2,2]
C0086388
Physiology Pulmonary
Descripción

Physiology Pulmonary

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0031842
UMLS CUI [1,2]
C0024109
Quality of Life
Descripción

CHSA ( Child Health Survey for Asthma), PAQLQ (Pediatric Asthma Quality of Life Questionnaire), Pediatric Caregiver AQLQ ( Pediatric Caregiver Asthma Quality of Life Questionnaire), PedsQL 3.0, Asthma Module ( Pediatric Quality of Life Inventory)

Tipo de datos

text

Alias
UMLS CUI [1]
C0034380
PACD (daily diary)
Descripción

PACD,Pediatric Asthma Caregiver Diary

Tipo de datos

text

Alias
UMLS CUI [1]
C1457887
Prospective clinical trial efficacy/ effectiveness outcomes
Descripción

Prospective clinical trial efficacy/ effectiveness outcomes

Alias
UMLS CUI-1
C0008976
UMLS CUI-2
C1280519
Biomarkers
Descripción

Biomarkers

Tipo de datos

text

Alias
UMLS CUI [1]
C0005516
cACT
Descripción

cACT (childhood Asthma Control Test)

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0449820
UMLS CUI [1,2]
C0205199
Exacerbation of asthma
Descripción

Exacerbation of asthma

Tipo de datos

text

Alias
UMLS CUI [1]
C0349790
Healthcare Utilization and Costs
Descripción

Utilization healthcare; Costs healthcare

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0042153
UMLS CUI [1,2]
C0086388
UMLS CUI [2,1]
C0010186
UMLS CUI [2,2]
C0086388
Physiology Pulmonary
Descripción

Physiology Pulmonary

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0031842
UMLS CUI [1,2]
C0024109
Quality of Life
Descripción

CHSA ( Child Health Survey for Asthma), PAQLQ (Pediatric Asthma Quality of Life Questionnaire), Pediatric Caregiver AQLQ ( Pediatric Caregiver Asthma Quality of Life Questionnaire), PedsQL 3.0, Asthma Module ( Pediatric Quality of Life Inventory)

Tipo de datos

text

Alias
UMLS CUI [1]
C0034380
PACD (daily diary)
Descripción

PACD Pediatric Asthma Caregiver Diary

Tipo de datos

text

Alias
UMLS CUI [1]
C1457887
Observational study outcomes
Descripción

Observational study outcomes

Alias
UMLS CUI-1
C1518527
UMLS CUI-2
C0086749
Biomarkers
Descripción

Biomarkers

Tipo de datos

text

Alias
UMLS CUI [1]
C0005516
Healthcare Utilization and Costs
Descripción

Utilization healthcare; Costs healthcare

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0042153
UMLS CUI [1,2]
C0086388
UMLS CUI [2,1]
C0010186
UMLS CUI [2,2]
C0086388
Physiology Pulmonary
Descripción

Physiology Pulmonary

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0031842
UMLS CUI [1,2]
C0024109
Quality of Life
Descripción

CHSA ( Child Health Survey for Asthma), PAQLQ (Pediatric Asthma Quality of Life Questionnaire), Pediatric Caregiver AQLQ ( Pediatric Caregiver Asthma Quality of Life Questionnaire), PedsQL 3.0, Asthma Module ( Pediatric Quality of Life Inventory)

Tipo de datos

text

Alias
UMLS CUI [1]
C0034380
PACD (daily diary)
Descripción

PACD Pediatric Asthma Caregiver Diary

Tipo de datos

text

Alias
UMLS CUI [1]
C1457887

Similar models

Table V- Supplemental Asthma Outcomes NIH AHRQ for children

Name
Tipo
Description | Question | Decode (Coded Value)
Tipo de datos
Alias
Item Group
Characterization of study population for prospective clinical trials
C2348561 (UMLS CUI-1)
C1880022 (UMLS CUI-2)
C0008976 (UMLS CUI-4)
Item
Biomarkers
text
C0005516 (UMLS CUI [1])
Code List
Biomarkers
CL Item
FeNO (1)
CL Item
 Sputum eosinophils (2)
CL Item
 CBC (total eosinophils) (3)
CL Item
 Total IgE (4)
CL Item
 Allergen­specific IgE (5)
CL Item
Urinary LTE4 (6)
Item
Exacerbation of asthma
text
C0349790 (UMLS CUI [1])
Code List
Exacerbation of asthma
CL Item
For trials in the acute management of exacerbations (ED setting):  Validated assessment tools, such as PASS, PS, PRAM, CAS, PI, ASS=PASS, PS, PRAM, CAS, PI, ASS (1)
CL Item
For trials in the acute management of exacerbations (ED setting): FEV1 (ages 5­11 years, as feasible) (2)
CL Item
 Any prior exacerbation (3)
CL Item
 Any prior ICU admission/intubation (4)
CL Item
SES of the study population (5)
Item
Healthcare Utilization and Costs
text
C0042153 (UMLS CUI [1,1])
C0086388 (UMLS CUI [1,2])
C0010186 (UMLS CUI [2,1])
C0086388 (UMLS CUI [2,2])
Code List
Healthcare Utilization and Costs
CL Item
 Categorization of asthma­-specific outpatient visits: Scheduled primary care (1)
CL Item
Categorization of asthma­-specific outpatient visits: Unscheduled primary care (2)
CL Item
Categorization of asthma­-specific outpatient visits: Scheduled Specialty care (3)
CL Item
Categorization of asthma­-specific outpatient visits: Unscheduled Specialty care (4)
CL Item
 Respiratory healthcare use (pneumonia, bronchitis, etc) (5)
CL Item
Asthma school absences (6)
CL Item
Asthma work absences (7)
Item
Physiology Pulmonary
text
C0031842 (UMLS CUI [1,1])
C0024109 (UMLS CUI [1,2])
Code List
Physiology Pulmonary
CL Item
PEF monitoring (1)
CL Item
Airway responsiveness (2)
CL Item
 Lung volumes (3)
CL Item
Gas exchange (4)
Item
Quality of Life
text
C0034380 (UMLS CUI [1])
Code List
Quality of Life
CL Item
 CHSA  (1)
CL Item
 PAQLQ  (2)
CL Item
Pediatric Caregiver AQLQ  (3)
CL Item
PedsQL 3.0, Asthma Module (4)
Symptoms
Item
PACD (daily diary)
text
C1457887 (UMLS CUI [1])
Item Group
Prospective clinical trial efficacy/ effectiveness outcomes
C0008976 (UMLS CUI-1)
C1280519 (UMLS CUI-2)
Item
Biomarkers
text
C0005516 (UMLS CUI [1])
Code List
Biomarkers
CL Item
FeNO (1)
CL Item
 Sputum eosinophils (2)
CL Item
 CBC (total eosinophils) (3)
CL Item
 Total IgE (4)
CL Item
 Allergen­specific IgE (5)
CL Item
Urinary LTE4 (6)
Composite Scores
Item
cACT
text
C0449820 (UMLS CUI [1,1])
C0205199 (UMLS CUI [1,2])
Item
Exacerbation of asthma
text
C0349790 (UMLS CUI [1])
Code List
Exacerbation of asthma
CL Item
For trials in the acute management of exacerbations (ED setting):  Validated assessment tools, such as PASS, PS, PRAM, CAS, PI, ASS=PASS, PS, PRAM, CAS, PI, ASS (1)
CL Item
For trials in the acute management of exacerbations (ED setting): FEV1 (ages 5­11 years, as feasible) (2)
Item
Healthcare Utilization and Costs
text
C0042153 (UMLS CUI [1,1])
C0086388 (UMLS CUI [1,2])
C0010186 (UMLS CUI [2,1])
C0086388 (UMLS CUI [2,2])
Code List
Healthcare Utilization and Costs
CL Item
 Categorization of asthma­specific outpatient visits: Scheduled primary care (1)
CL Item
Categorization of asthma­specific outpatient visits: Unscheduled primary care (2)
CL Item
Categorization of asthma­specific outpatient visits: Scheduled Specialty care (3)
CL Item
Categorization of asthma­specific outpatient visits: Unscheduled Specialty care (4)
CL Item
 Respiratory healthcare use  (5)
CL Item
Asthma school absences (6)
CL Item
Asthma work presenteeism and absenteeism (WPAI instrument) (7)
CL Item
Cost analysis and cost­ effectiveness analysis (8)
Item
Physiology Pulmonary
text
C0031842 (UMLS CUI [1,1])
C0024109 (UMLS CUI [1,2])
Code List
Physiology Pulmonary
CL Item
PEF monitoring (1)
CL Item
Airway responsiveness (2)
CL Item
 Lung volumes (3)
CL Item
Gas exchange (4)
CL Item
Spirometry (pre­ and post­ bronchodilator) (5)
Item
Quality of Life
text
C0034380 (UMLS CUI [1])
Code List
Quality of Life
CL Item
 CHSA  (1)
CL Item
 PAQLQ  (2)
CL Item
Pediatric Caregiver AQLQ  (3)
CL Item
PedsQL 3.0, Asthma Module (4)
Item
PACD (daily diary)
text
C1457887 (UMLS CUI [1])
Code List
PACD (daily diary)
Item Group
Observational study outcomes
C1518527 (UMLS CUI-1)
C0086749 (UMLS CUI-2)
Item
Biomarkers
text
C0005516 (UMLS CUI [1])
Code List
Biomarkers
CL Item
FeNO (1)
CL Item
 Sputum eosinophils (2)
CL Item
 CBC (total eosinophils) (3)
CL Item
 Total IgE (4)
CL Item
 Allergen­specific IgE (5)
CL Item
Urinary LTE4 (6)
Item
Healthcare Utilization and Costs
text
C0042153 (UMLS CUI [1,1])
C0086388 (UMLS CUI [1,2])
C0010186 (UMLS CUI [2,1])
C0086388 (UMLS CUI [2,2])
Code List
Healthcare Utilization and Costs
CL Item
 Categorization of asthma­specific outpatient visits: Scheduled primary care (1)
CL Item
Categorization of asthma­specific outpatient visits: Unscheduled primary care (2)
CL Item
Categorization of asthma­specific outpatient visits: Scheduled Specialty care (3)
CL Item
Categorization of asthma­specific outpatient visits: Unscheduled Specialty care (4)
CL Item
 Respiratory healthcare use  (5)
CL Item
Asthma school absences (6)
CL Item
Asthma work presenteeism and absenteeism (WPAI instrument) (7)
CL Item
Cost analysis and cost­ effectiveness analysis (8)
Item
Physiology Pulmonary
text
C0031842 (UMLS CUI [1,1])
C0024109 (UMLS CUI [1,2])
Code List
Physiology Pulmonary
CL Item
PEF monitoring (1)
CL Item
Airway responsiveness (2)
CL Item
 Lung volumes (3)
CL Item
Gas exchange (4)
Item
Quality of Life
text
C0034380 (UMLS CUI [1])
Code List
Quality of Life
CL Item
 CHSA  (1)
CL Item
 PAQLQ  (2)
CL Item
Pediatric Caregiver AQLQ  (3)
CL Item
PedsQL 3.0, Asthma Module (4)
Symptoms
Item
PACD (daily diary)
text
C1457887 (UMLS CUI [1])

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