ID

12095

Description

Derived from: Malcovati L, Hellström-Lindberg E, Bowen D, Adès L, Cermak J, Del Cañizo C, Della Porta MG, Fenaux P, Gattermann N, Germing U, Jansen JH, Mittelman M, Mufti G, Platzbecker U, Sanz GF, Selleslag D, Skov-Holm M, Stauder R, Symeonidis A, van de Loosdrecht AA, de Witte T, Cazzola M; European Leukemia Net. Diagnosis and treatment of primary myelodysplastic syndromes in adults: recommendations from the European LeukemiaNet. Blood. 2013 Oct 24;122(17):2943-64 http://www.ncbi.nlm.nih.gov/pubmed/23980065

Link

http://www.ncbi.nlm.nih.gov/pubmed/23980065

Keywords

Versions (1)
  1. 9/22/15 9/22/15 - Martin Dugas
Uploaded on

September 22, 2015

DOI

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License

Creative Commons BY-NC 3.0 Legacy
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Therapeutic algorithm for adult patients with primary MDS and and low IPSS risk score

English

Therapeutic algorithm for adult patients with primary MDS and and low IPSS risk score

1 forms  
Adult patient with primary MDS and and low IPSS risk score
Description

Adult patient with primary MDS and and low IPSS risk score

Alias
UMLS CUI-1
C0280451
UMLS CUI-2
C2827405
UMLS CUI-3
C3538919
1. Low IPSS risk
Description

Low IPSS risk

Data type

text

Alias
UMLS CUI [1,1]
C2827405
UMLS CUI [1,2]
C3538919
2. Symptomatic anemia
Description

Symptomatic anemia

Data type

text

Alias
UMLS CUI [1]
C0741011
3. MDS del(5q)
Description

MDS del(5q)

Data type

text

Alias
UMLS CUI [1]
C1292779
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Similar models

Therapeutic algorithm for adult patients with primary MDS and and low IPSS risk score

1 forms
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
Adult patient with primary MDS and and low IPSS risk score
C0280451 (UMLS CUI-1)
C2827405 (UMLS CUI-2)
C3538919 (UMLS CUI-3)
Item
1. Low IPSS risk
text
C2827405 (UMLS CUI [1,1])
C3538919 (UMLS CUI [1,2])
1
Code List
1. Low IPSS risk
CL Item
Asymptomatic cytopenia -> Watchful waiting (1)
C0010828 (UMLS CUI-1)
C0231221 (UMLS CUI-2)
CL Item
Symptomatic anemia -> step 2 (2)
C0741011 (UMLS CUI-1)
Item
2. Symptomatic anemia
text
C0741011 (UMLS CUI [1])
Symptomatic anemia
Code List
2. Symptomatic anemia
CL Item
sEpo < 500 mU/mL and/or RBC units < 2/month -> rHuEpo +/- G-CSF (2)
CL Item
MDS del(5q) -> step 3 (3)
C1292779 (UMLS CUI-1)
CL Item
RBC transfusion and iron chelation therapy (4)
C0086252 (UMLS CUI-1)
C0598126 (UMLS CUI-2)
CL Item
Age < 60 years, BM blasts < 5%, normal cytogenetics, transfusion-dependency (hypocellular bone marrow) -> Immunosuppressive therapy with ATG plus CSA (5)
Item
3. MDS del(5q)
text
C1292779 (UMLS CUI [1])
MDS del(5q)
Code List
3. MDS del(5q)
CL Item
sEpo >=500 mU/mL and RBC units >=2/month -> Lenalidomide (within prospective registry) (3)
CL Item
sEpo < 500 mU/mL and/or RBC units <2/month -> rHuEpo +/- G-CSF -> Lenalidomide (within prospective registry) (4)
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