ID

12095

Beschrijving

Derived from: Malcovati L, Hellström-Lindberg E, Bowen D, Adès L, Cermak J, Del Cañizo C, Della Porta MG, Fenaux P, Gattermann N, Germing U, Jansen JH, Mittelman M, Mufti G, Platzbecker U, Sanz GF, Selleslag D, Skov-Holm M, Stauder R, Symeonidis A, van de Loosdrecht AA, de Witte T, Cazzola M; European Leukemia Net. Diagnosis and treatment of primary myelodysplastic syndromes in adults: recommendations from the European LeukemiaNet. Blood. 2013 Oct 24;122(17):2943-64 http://www.ncbi.nlm.nih.gov/pubmed/23980065

Link

http://www.ncbi.nlm.nih.gov/pubmed/23980065

Trefwoorden

  1. 22-09-15 22-09-15 - Martin Dugas
Geüploaded op

22 september 2015

DOI

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Licentie

Creative Commons BY-NC 3.0 Legacy

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Therapeutic algorithm for adult patients with primary MDS and and low IPSS risk score

Therapeutic algorithm for adult patients with primary MDS and and low IPSS risk score

Adult patient with primary MDS and and low IPSS risk score
Beschrijving

Adult patient with primary MDS and and low IPSS risk score

Alias
UMLS CUI-1
C0280451
UMLS CUI-2
C2827405
UMLS CUI-3
C3538919
1. Low IPSS risk
Beschrijving

Low IPSS risk

Datatype

text

Alias
UMLS CUI [1,1]
C2827405
UMLS CUI [1,2]
C3538919
2. Symptomatic anemia
Beschrijving

Symptomatic anemia

Datatype

text

Alias
UMLS CUI [1]
C0741011
3. MDS del(5q)
Beschrijving

MDS del(5q)

Datatype

text

Alias
UMLS CUI [1]
C1292779

Similar models

Therapeutic algorithm for adult patients with primary MDS and and low IPSS risk score

Name
Type
Description | Question | Decode (Coded Value)
Datatype
Alias
Item Group
Adult patient with primary MDS and and low IPSS risk score
C0280451 (UMLS CUI-1)
C2827405 (UMLS CUI-2)
C3538919 (UMLS CUI-3)
Item
1. Low IPSS risk
text
C2827405 (UMLS CUI [1,1])
C3538919 (UMLS CUI [1,2])
Code List
1. Low IPSS risk
CL Item
Asymptomatic cytopenia -> Watchful waiting (1)
C0010828 (UMLS CUI-1)
C0231221 (UMLS CUI-2)
CL Item
Symptomatic anemia -> step 2 (2)
C0741011 (UMLS CUI-1)
Item
2. Symptomatic anemia
text
C0741011 (UMLS CUI [1])
Code List
2. Symptomatic anemia
CL Item
sEpo < 500 mU/mL and/or RBC units < 2/month -> rHuEpo +/- G-CSF (2)
CL Item
MDS del(5q) -> step 3 (3)
C1292779 (UMLS CUI-1)
CL Item
RBC transfusion and iron chelation therapy (4)
C0086252 (UMLS CUI-1)
C0598126 (UMLS CUI-2)
CL Item
Age < 60 years, BM blasts < 5%, normal cytogenetics, transfusion-dependency (hypocellular bone marrow) -> Immunosuppressive therapy with ATG plus CSA (5)
Item
3. MDS del(5q)
text
C1292779 (UMLS CUI [1])
Code List
3. MDS del(5q)
CL Item
sEpo >=500 mU/mL and RBC units >=2/month -> Lenalidomide (within prospective registry) (3)
CL Item
sEpo < 500 mU/mL and/or RBC units <2/month -> rHuEpo +/- G-CSF -> Lenalidomide (within prospective registry) (4)

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