ID
11710
Descripción
Through last couple of years the number of patients treated for acute coronary event without persistent ST segment elevation in ECG has been growing. This is probably an effect of improving diagnostics of myocardial infraction without persistent ST segment elevation in ECG, due to routine Troponin serum level evaluation and better primary prevention. This fact makes the search for the optimal treatment for patients with acute coronary event without persistent ST segment elevation in ECG, including both patients intended for pharmacological and invasive treatment percutaneous coronary intervention (PCI) or coronary artery byppass grafting (CABG). Patients undergoing invasive treatment for acute coronary event, have higher risk rate, than those with stabile angina pectoris. The authors of this study want to evaluate, whether the proportional use of platelet GP IIb/IIIa receptor antagonist - eptifibatide in patients undergoing CABG results in improvement of short-, and long time results in those patients. Eptifibatide ( Integrilin) a cyclic heptapeptide antagonist of the GP IIb/IIIa integrin receptor, is an intravenous antagonist with rapid onset and short half-life. https://clinicaltrials.gov/ct2/show/NCT01863134
Link
https://clinicaltrials.gov/ct2/show/NCT01863134
Palabras clave
Versiones (1)
- 28/7/15 28/7/15 -
Subido en
28 de julio de 2015
DOI
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Licencia
Creative Commons BY 4.0
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Eligibility Eptifibatide Acute Coronary Syndrome NCT01863134
Eligibility criteria
- StudyEvent: ODM
Descripción
Exclusion Criteria
Descripción
Women who are pregnant or nursing.
Tipo de datos
boolean
Alias
- UMLS CUI-1
- C0549206
Descripción
Angina lasting longer than 24h
Tipo de datos
boolean
Alias
- UMLS CUI-1
- C0002962
Descripción
ST segment elevation - Pardy wave
Tipo de datos
boolean
Alias
- UMLS CUI-1
- C0520886
Descripción
age over 75 years
Tipo de datos
boolean
Alias
- UMLS CUI-1
- C0001779
Descripción
history of revascularization procedure during last 6 months (PTCA, CABG)
Tipo de datos
boolean
Alias
- UMLS CUI-1
- C0027056
Descripción
chronic heart failure (NYHA III or IV) during pre-hospitalization period
Tipo de datos
boolean
Alias
- UMLS CUI-1
- C0018802
Descripción
History of bleeding from gastrointestinal tract system during last 30 days
Tipo de datos
boolean
Alias
- UMLS CUI-1
- C0017181
Descripción
History of bleeding from genitourinary system during last 30 days
Tipo de datos
boolean
Alias
- UMLS CUI-1
- C0919591
Descripción
history of intracranial lesions or stroke
Tipo de datos
boolean
Alias
- UMLS CUI-1
- C0559159
Descripción
history of major surgery during last 6 weeks
Tipo de datos
boolean
Alias
- UMLS CUI-1
- C0679637
Descripción
history of trauma during last 6 weeks
Tipo de datos
boolean
Alias
- UMLS CUI-1
- C3714660
Descripción
history of hemorrhagic diathesis
Tipo de datos
boolean
Alias
- UMLS CUI-1
- C3251812
Descripción
thrombocytopenia < 100 000/mm3
Tipo de datos
boolean
Alias
- UMLS CUI-1
- C0040034
Descripción
anticoagulant therapy with INR>2,0
Tipo de datos
boolean
Alias
- UMLS CUI-1
- C0003280
Descripción
significant hepatic failure
Tipo de datos
boolean
Alias
- UMLS CUI-1
- C0085605
Descripción
significant renal failure with serum creatinine>2,0 mg%
Tipo de datos
boolean
Alias
- UMLS CUI-1
- C0035078
Descripción
elevated blood pressure: SBP>200mmHg and/or DBP>110mmHg despite the antihypertensive treatment
Tipo de datos
boolean
Alias
- UMLS CUI-1
- C0020538
Descripción
allergy to drugs or any therapeutic agent
Tipo de datos
boolean
Alias
- UMLS CUI-1
- C0013182
Similar models
Eligibility criteria
- StudyEvent: ODM