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DELCODE: DZNE – Longitudinal Cognitive Impairment and Dementia Study - 8‐Meter‐Walking‐Test (8MWT), 9‐hole peg Test (9HPT)

- 22/04/2020 - 1 Formulaire, 3 Groupes Item, 25 Eléments de données, 1 Langue
Groupes Item: Administrative Data, 8‐Meter‐Walking‐Test (8MWT), 9‐hole peg Test (9HPT)
DELCODE is conducted by DZNE, the German Center for Neurodegenerative Diseases within the Helmholtz Association. The following information was taken from https://www.dzne.de/en/research/studies/clinical-studies/delcode/. Background and aims: One of the important aims of research into Alzheimer's is to find ways of detecting the disease early – if at all possible, as soon as the first minor symptoms appear, or even before any symptoms at all have appeared. Such detection capabilities are the necessary basis for development of therapies that can be applied at such early stages in the disease. Recent research indicates that such therapies could be more effective than therapies initiated during the disease's later stages. Over a period of several years, the DELCODE study is studying persons in early stages of the disease, along with various risk groups. The research is aimed at the development of procedures for characterizing early stages of the disease, at improving prediction of the course of the disease and at identifying new markers for early diagnosis of Alzheimer's-related dementia. Overview: DELCODE is set up to run for an initial period of three years, and to include a total of 1,000 study participants, who will be examined on a yearly basis. The group of participants will include persons with no complaints (healthy control subjects), patients with slight memory impairment or mild dementia and first-degree relatives of patients with diagnosed Alzheimer's disease. The minimum age for participants is 60. Course of the study: The examinations in the framework of the study will include a comprehensive interview carried out by a study investigator, a detailed neuropsychological examination (testing of memory functions and other areas of cognitive performance), a blood test and a cranial MRI scan. Optionally, subject to the study participant's consent in each case, a lumbar puncture (collection of cerebrospinal fluid) will be carried out." For more information (e.g. principle investigator and study coordination), please visit the above link or https://www.dzne.de. This document contains the 8‐Meter‐Walking‐Test (8MWT) and the 9‐hole peg Test (9HPT). It has to be filled in for baseline and for all follow-ups.

DZHK Data Catalogue - Spiroergometry

- 16/10/2019 - 1 Formulaire, 2 Groupes Item, 46 Eléments de données, 2 Langues
Groupes Item: Cardiopulmonary exercise testing details, Cardiopulmonary Exercise Test
With permission from the DZHK administrative office. http://dzhk.de The DZHK (Deutsches Zentrum für Herz-Kreislauf-Forschung e.V.; German Center for Cardiovascular Research) is a joint cooperation of twenty-eight institutions in seven locations throughout Germany to develop a common research strategy. They developed a data catalogue with metadata and data as well as information about available biological materials from all their studies. For more information on the data catalogue and access to actual data and biosamples please visit https://dzhk.de/en/resources/data-manual/ . This version contains the metadata part only. The module Spiroergometry is used to document spiroergometry examinations. The cardiopulmonary exercise test analyses the reactions and the interplay of the heart, circulation, breathing and metabolism during gradually increasing exercise, both in terms of qualitative and quantitative measures. The cardiopulmonary exercise test should be the last test performed on the examination day. This form uses the Borg scales of dyspnoea (Borg, G.A., Psychophysical bases of perceived exertion. Medicine and science in sports and exercise, 1982. 14(5): p. 377-81) and exertion (Borg, G., Anstrengungsempfinden und körperliche Aktivität. Dtsch Arztebl International, 2004. 101(15): p. 1016-). The documentation is to be performed according to the DZHK's SOPs, which can be accessed at https://dzhk.de/en/resources/sops/ (or https://dzhk.de/ressourcen/sops/ for the German language versions). The SOPs for this form are "Cardiopulmonary exercise test (spiroergometry)" (version 1.1, effective as of 01/07/2017), and "Spiroergometrie " (version 1.1, effective as of 01/07/2015), for the English and German versions, respectively. Inclusion Criteria: All subjects who are capable of cycling on an ergometer or of doing exercise on a treadmill and to whom no exclusion criteria apply can take part. Special inclusion criteria are stipulated in the study protocol of the respective study/register. Exclusion criteria: Absolute contraindications: • Acute relevant disease, e.g. recent myocardial infarction, systemic infections, thromboses or embolisms, acute exacerbation of a respiratory disease. • Severe cardiac arrhythmia or blocks (second- or third-degree AV block). • Insufficiently controlled arterial hypertension (RRsyst >170 mmHg, and/or RRdiast >110 mmHg). • Known symptomatic or severe aortic stenosis. Relative contraindications: • Tachycardia at rest (>120 bpm). • Poorly managed epilepsy with the risk of provoking a seizure through exercise. • Symptomatic electrolyte imbalance or metabolic imbalance. • Symptomatic impaired cerebral circulation. If necessary, specific criteria of the respective studies or registers have to be observed.

DZHK Data Catalogue - 6-Minute Walking Test

- 08/10/2019 - 1 Formulaire, 4 Groupes Item, 23 Eléments de données, 2 Langues
Groupes Item: 6 Minute Walking Test details, Examination, Borg Scale, Aids/Examination equipment and 6MWT stop criteria
With permission from the DZHK administrative office. http://dzhk.de The DZHK (Deutsches Zentrum für Herz-Kreislauf-Forschung e.V.; German Center for Cardiovascular Research) is a joint cooperation of twenty-eight institutions in seven locations throughout Germany to develop a common research strategy. They developed a data catalogue with metadata and data as well as information about available biological materials from all their studies. For more information on the data catalogue and access to actual data and biosamples please visit https://dzhk.de/en/resources/data-manual/ . This version contains the metadata part only. The form6-Minute Walking Test is used to document the results of the 6-minute walking test. The test evaluates the functional reserves and the degree of physical tolerance of patients with chronic heart and lung diseases in their individual daily life as well as it records the course of the disease and the success of therapeutic measures. The time between this test and other physical stress tests (e.g. ergometry or cardiovascular exercise test) should not be less than 2 hours; ideally, the examination should be performed on a different day. This form uses the Borg scales of dyspnoea (Borg, G.A., Psychophysical bases of perceived exertion. Medicine and science in sports and exercise, 1982. 14(5): p. 377-81) and exertion (Borg, G., Anstrengungsempfinden und körperliche Aktivität. Dtsch Arztebl International, 2004. 101(15): p. 1016-). The documentation is to be performed according to the DZHK's SOPs, which can be accessed at https://dzhk.de/en/resources/sops/ (or https://dzhk.de/ressourcen/sops/ for the German language versions). The SOP for this form is "6-minute walking test (6MWT)" (version 1.0, valid as of 01/09/2014) for the English language version, and "6-Minuten-Gehtest (6MWT)" (version 1.0, valid as of 01/09/2014) for the German version.

Exercise-Stress-Test report University Hospital Muenster (UKM) - Exercise-Stress-Test report

- 30/09/2016 - 1 Formulaire, 3 Groupes Item, 29 Eléments de données, 1 Langue
Groupes Item: Demographic Information, Baseline, Stress-Test
Hospital Clinical trial Documentation Form at the University Hospital Muenster. Original Form name: Belastungsprotokoll MSZ

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