- 13/04/2021 - 1 Formulário, 1 Grupo de itens, 3 Elementos de dados, 2 Idiomas
Grupo de itens: Pain NRS
- 05/06/2023 - 5 Formulários, 1 Grupo de itens, 2 Elementos de dados, 1 Idioma
Grupo de itens: IG.elig
Principal Investigator: Theodore J. Price, School of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, TX, USA MeSH: Chronic Pain,Neuralgia https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001158 RNA sequencing was performed on human DRGs and relative gene abundances were calculated. Various analyses were performed: - Human DRG gene expression profiles were contrasted with a panel of gene expression profiles of relevant tissues in human and mouse ( integrating, among other sources, datasets from ENCODE and GTex ) in order to identify. ol type="a"- DRG-enriched gene expression, co-expression modules of DRG-expressed genes, and key transcriptional regulators in humans. - Contrasting the human and mouse DRG transcriptomes to identify DRG-enriched gene expression patterns that were conserved between human and mouse, identifying putative cell types of expression of these genes, and potential known drugs that might target the corresponding gene products. - Characterization of non-coding RNA profile of human and mouse DRGs. - Characterization of DRG-enriched alternative splicing and alternative transcription start site usage based transcript variants in humans and mouse, and the overlap between these two species. - Contrasting of human DRG and GTex human tibial nerve samples to identify putative axonally transported mRNAs in sensory neurons. - Human DRG transcriptomes from donors suffering from neuropathic and/or chronic pain were contrasted with controls to identify. ol type="a"- Differentially expressed genes, pathways and regulators path play a potential role in neuronal plasticity, electrophysiological activity, immune signaling and response. liPredictive models (Random Forests) were built to jointly predict the sex and pain state of samples based on information contained solely in autosomal gene expression profile./li liGene co-expression modules were identified and gene set enrichment analysis performed.to identify sample - pathway associations, and to broadly characterize plasticity in human DRG cell types./li /ol

pht005592.v2.p1

1 Grupo de itens 5 Elementos de dados

pht005593.v2.p1

1 Grupo de itens 5 Elementos de dados

pht005594.v2.p1

1 Grupo de itens 16 Elementos de dados

pht005595.v2.p1

1 Grupo de itens 10 Elementos de dados
- 09/05/2022 - 1 Formulário, 1 Grupo de itens, 20 Elementos de dados, 2 Idiomas
Grupo de itens: Chronische Schmerzen
Der Fragebogen dient der Messung von Aspekten der "Schmerzakzeptanz", definiert als "Bemühungen, das eigene Funktionsniveau trotz bestehender Einschränkungen zu erhalten sowie die Tendenz, Schmerzen nicht um jeden Preis vermeiden zu wollen" (Nilges et al., 2007, S. 60). Personen mit hoher Schmerzakzeptanz richten demnach ihren Aufmerksamkeitsfokus weniger auf den Schmerz und dessen Beseitigung als vielmehr auf Möglichkeiten, trotz gewisser schmerzbedingter Beeinträchtigungen aktiv am privaten, sozialen und beruflichen Leben teilzuhaben. Der CPAQ-D enthält 20 Aussagen, sich auf den Umgang mit bzw. die Bewertung von chronischen Schmerzen beziehen. Sie sind zu zwei Subskalen zusammengefasst: (1) Aktivitätsbereitschaft (AB; k = 10) und (2) Schmerzbereitschaft (SB; k = 8). Reliabilität: Cronbachs Alpha beträgt Alpha = .84-.87. Validität: Beide CPAQ-D-Subskalen und die Gesamtskala korrelierten moderat bis hoch negativ mit Indikatoren psychischer Belastung (z. B. ADS-L, HADS-D, CSQ, PDI, SES). Hingegen zeigten sich keine oder nur geringe Zusammenhänge mit weiteren Schmerzmaßen, z. B. dem Chronifizierungsstadium nach dem Mainzer Stadienkonzept chronischer Schmerzen, der sensorischen Schmerzintensität, der bisherigen Schmerzdauer in Jahren und weiteren Indikatoren der Schmerzintensität sowie experimentell erfassten Unterschieden in der thermischen Schmerzschwelle. Zudem ließ sich kein Zusammenhang zwischen der momentanen Schmerzstärke und der Schmerzakzeptanz nachweisen (r = .16). https://doi.org/10.23668/psycharchives.4574
- 17/09/2021 - 1 Formulário, 5 Grupos de itens, 63 Elementos de dados, 1 Idioma
Grupos de itens: Pre-evaluation questions, When you answer questions in the following pages about “your significant other”, always respond in reference to the specific person you just indicated above., Pain effect on life, Significant other response pain, frequency daily activities
Kerns, R.D., Turk, D.C., & Rudy, T.E. (1985). The West Haven-Yale Multidimensional Pain Inventory (WHYMPI/MPI). Measurement Instrument Database for the Social Science. Retrieved 30.08.2020, from www.midss.ie Primary use / Purpose: The West Haven-Yale Multidimensional Pain Inventory (WHYMPI/MPI) is designed to provide a brief, psychometrically-sound, and comprehensive assessment of the important components of the chronic pain experience. The instrument is recommended for use as part of behavioral and psychological assessment strategies in the evaluation of chronic pain patients in a clinical or research setting. Background: The West Haven-Yale Multidimensional Pain Inventory (WHYMPI/MPI; Kerns, Turk, and Rudy, 1985) is a 52-item, 12-scale inventory that is divided into three parts. Part I includes five scales designed to measure important dimensions of the chronic pain experience including; 1) perceived interference of pain in vocational, social/recreational, and family/marital functioning, 2) support or concern from spouse or significant other, 3) pain severity, 4) perceived life control, and 5) affective distress. Part II assesses patients’ perceptions of the degree to which spouses or significant others display Solicitous, Distracting or Negative responses to their pain behaviors and complaints. Part III assesses patients’ report of the frequency with which they engage in four categories of common everyday activities; Household Chores, Outdoor Work, Activities Away from Home, and Social Activities. In addition to the individual scale scores, a General Activity scale score, obtained from the combination of all four activity scale scores, has been recommended for some purposes (Turk & Rudy, 1990). Patient’s responses to WHYMPI items are made on a 7-point scale. Psychometrics: Kerns, Turk and Rudy (1985) demonstrated that the internal reliability coefficients of all WHYMPI scales range from .70 to .90; the test-retest reliabilities of these scales over a 2-week interval range from .62 to .91. The validity of the WHYMPI has been supported by the results of confirmatory and exploratory factor analytic procedures. The procedures revealed that the WHYMPI scales were significantly correlated with several criterion measures of anxiety, depression, marital satisfaction, pain severity, and health locus of control. Digital Object Identifier (DOI): http://dx.doi.org/10.13072/midss.256 Compendium: Reference: Kerns, R.D., Turk, D.C., & Rudy, T.E. (1985). The West Haven-Yale Multidimensional Pain Inventory (WHYMPI). Pain, 23, 345-356. Language: English Contact Name and Address: Robert D. Kerns, Ph.D. Chief, Psychology Service VA Connecticut HCS, 950 Campbell Avenue West Haven, CT 06516. Copyright: Copyright © 1985, Robert D. Kerns, Dennis C. Turk, and Thomas E. Rudy. 1. Origin: The instrument is original. It is theoretically linked to the cognitive-behavioral conceptualization of chronic pain (Turk et al., 1983) and health assessment (Turk & Kerns, 1985). 2. Purpose: The West Haven-Yale Multidimensional Pain Inventory (WHYMPI/MPI) is designed to provide a brief, psychometrically-sound, and comprehensive assessment of the important components of the chronic pain experience. 3. Population: The WHYMPI has been demonstrated to be applicable across a variety of clinical pain conditions including chronic low back pain, temporomandibular disorders, headaches (Turk & Rudy; 1988; 1990), fibromyalgia (Turk et al., 1996), and cancer pain (Turk et al., 1998a). The WHYMPI has been demonstrated to be sensitive to change following rehabilitation (Kerns & Haythornthwaite, 1988; Kerns, Turk, Holzman & Rudy, 1986; Turk et al., 1993; Turk et al., 1998b). Its brevity, validity/reliability, self-report nature and ease of scoring make it ideal for both clinical and research purposes. The WHYMPI has been used cross culturally and has been translated into several languages including Swedish (Bergstrom et al., 1999), Dutch (Lousberg et al., 1999), German (Flor et al., 1990), Italian, Spanish, Portuguese, French, Icelandic, and Japanese. 4. Administration: Rater: The WHYMPI is a self-report questionnaire that may be administered by a qualified therapist or research assistant. Time required: 20 minutes Training: Individuals administering the WHYMPI should have an understanding of the subscales and how they relate to the cognitive-behavioral perspective of pain. Scoring: Hand scored. Part I Interference: (Question 2+3+4+8+9+13+14+17+19)/9 Support: (Question 5+10+15)/3 Pain Severity: (Question 1+7+12)/3 Life-Control: (Question 11+16)/2 Affective Distress: (6-Question 6) +18+20)/3 Part II Negative Responses: (Question 1+4+7+10)/4 Solicitous Responses: (Question 2+5+8+11+13+14)/6 Distracting Responses: (Question 3+6+9+12)/4 Part III Household Chores: (Question 1+5+9+13+17)/5 Outdoor Work: (Question 2+6+10+14+18)/5 Activities Away from Home: (Question 3+7+11+15)/4 Social Activities: (Question 4+8+12+16)/4 General Activity: (Sum of all questions in Part III)/18 *** To account for sporadic missing data, sums should be divided by the number of non-missing items. Any scale with more than 25% of its items missing should be considered missing. 5. Description: The WHYMPI (Kerns, Turk, and Rudy, 1985) is a 52-item, 12-scale inventory that is divided into three parts. Part I includes five scales designed to measure important dimensions of the chronic pain experience including; 1) perceived interference of pain in vocational, social/recreational, and family/marital functioning, 2) support or concern from spouse or significant other, 3) pain severity, 4) perceived life control, and 5) affective distress. Part II assesses patients’ perceptions of the degree to which spouses or significant others display Solicitous, Distracting or Negative responses to their pain behaviors and complaints. Part III assesses patients’ report of the frequency with which they engage in four categories of common everyday activities; Household Chores, Outdoor Work, Activities Away from Home, and Social Activities. In addition to the individual scale scores, a General Activity scale score, obtained from the combination of all four activity scale scores, has been recommended for some purposes (Turk & Rudy, 1990). Patient’s responses to WHYMPI items are made on a 7-point scale. 6. Coverage: The instrument is recommended for use as part of behavioral and psychological assessment strategies in the evaluation of chronic pain patients in a clinical or research setting. 7. Reliability: Kerns, Turk and Rudy (1985) demonstrated that the internal reliability coefficients of all WHYMPI scales range from .70 to .90; the test-retest reliabilities of these scales over a 2-week interval range from .62 to .91. 8. Validity: The validity of the WHYMPI has been supported by the results of confirmatory and exploratory factor analytic procedures. The procedures revealed that the WHYMPI scales were significantly correlated with several criterion measures of anxiety, depression, marital satisfaction, pain severity, and health locus of control 9. Responsiveness: Studies have demonstrated the sensitivity of the WHYMPI to improvements in pain and functioning (Kerns & Haythornthwaite, 1988; Kerns, Turk, Holzman & Rudy, 1986; Turk et al., 1993; Turk et al., 1998b); the ability of several of its scales to discriminate level of depressive symptom severity (Kerns & Haythornthwaite, 1988); the viability of the Pain Severity and Activity scales as brief and reliable measures of pain intensity and adaptive functioning (Holmes & Stevenson, 1990; Rudy, Turk, Kubinski, & Zaki, 1995); and the predictive utility of the Part II scales in the role of social interaction in the maintenance of pain and disability (Kerns, Haythornthwaite, Southwick, & Giller, 1990; Faucet & Levine, 1991). 10. Strengths: The strengths of the WHYMPI are its brevity, ease of administration, demonstrated reliability and validity, face validity and patient acceptance, and demonstrated utility in multiple clinical and research investigations. 11. Weakness: One weakness of the WHYMPI is that the Life-Control subscale is comprised of only two items. 12. Bibliography:
- 18/08/2020 - 1 Formulário, 10 Grupos de itens, 64 Elementos de dados, 1 Idioma
Grupos de itens: Information, Section One, Section Two, Section Three, Section Four, Section Five, Section Six, Section Seven, Section Eight, Section Nine
- 16/04/2014 - 1 Formulário, 2 Grupos de itens, 10 Elementos de dados, 2 Idiomas
Grupos de itens: Inclusion Criteria, Exclusion Criteria
- 15/04/2014 - 1 Formulário, 2 Grupos de itens, 10 Elementos de dados, 2 Idiomas
Grupos de itens: Inclusion Criteria, Exclusion Criteria
- 10/12/2013 - 1 Formulário, 2 Grupos de itens, 10 Elementos de dados, 2 Idiomas
Grupos de itens: Inclusion Criteria, Exclusion Criteria

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