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2 Zoekresultaten.

Effects of Varenicline on Smoking Lapse in Smokers With and Without Schizophrenia NCT01850953 - Eligibility

- 17-04-19 - 1 Formulier, 2 Itemgroepen, 15 Data-elementen, 1 Taal

Itemgroepen: Inclusion Criteria, Exclusion Criteria

The objective of this study is to determine the mechanisms by which varenicline, an effective smoking cessation treatment, protects against relapse. Varenicline will be administered in smokers with schizophrenia and control smokers using a randomized, double-blind, cross-over design. Smokers will be asked to stop smoking overnight; the next day the ability to resist smoking will be assessed in a laboratory smoking lapse paradigm. Measures of tobacco craving, reinforcement and withdrawal-related cognitive dysfunction will be correlated with time to lapse. The results could have significant clinical implications by identifying mechanisms by which smokers with schizophrenia are at more risk for relapse than the general population, leading to the development of more effective smoking cessation therapies. ODM derived from: https://clinicaltrials.gov/show/NCT01850953

Eligibility Smoking Cessation NCT00435370

- 25-06-17 - 1 Formulier, 2 Itemgroepen, 14 Data-elementen, 1 Taal

Itemgroepen: Inclusion Criteria, Exclusion Criteria

Effectiveness of Tropisetron Plus Risperidone for Improving Cognitive and Perceptual Disturbances in Schizophrenia; ODM derived from: https://clinicaltrials.gov/show/NCT00435370

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