REGIMS Multiple Sclerosis Immunotherapy Registry Version 2016

REGIMS is a registry of the administration, adverse events and benefit of immunotherapeutic agents in patients with Multiple Sclerosis. REGIMS is a project from the Institute of Epidemiology and Social Medicine of the University of Muenster, publication granted by Prof. Dr. Berger. For further information (in German), please view http://campus.uni-muenster.de/index.php?id=6075 or http://www.kompetenznetz-multiplesklerose.de/aktuelle-studien/regims. REGIMS ist ein Immuntherapieregister zur Verbesserung der Arzneimittelsicherheit in der Multiple Sklerose Therapie innerhalb des krankheitsbezogenen Kompetenznetzes MS. Das primäre Ziel von REGIMS ist die Erfassung der Häufigkeit, Charakteristika und Auswirkungen von Nebenwirkungen aktueller und neuer Immuntherapien in der klinischen Routinebehandlung der MS. Sekundäre Ziele sind die Auswertung von Faktoren, die a) mit Nebenwirkungen und b) mit guter Therapie-Adhärenz assoziiert sind. Optional können bei Zustimmung der Patienten Blutproben für die Biobank des KKNMS gesammelt werden. Patienten mit Multipler Sklerose (MS) weisen trotz des chronischen Verlaufs eine große Heterogenität klinischer Symptome, in Befunden der Bildgebung sowie pathophysiologischen Prozessen auf. Faktoren, die zur individuellen Krankheitsprognose beitragen sind kaum bekannt, jedoch hat die Einführung neuer Substanzen die Therapiemöglichkeiten der MS in den letzten Jahren deutlich erweitert. Die Anwendung sogenannter Immuntherapeutika (inklusive der neuen Substanzklasse der Biologika) bietet in der MS-Therapie eine Reihe von Chancen, birgt aber auch Risiken.

Baseline Main Sheet

Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
Inclusion-/Exclusion Criteria
C1516637 (UMLS CUI-1)
Visitendatum
Item
Visit date
date
C1320303 (UMLS CUI [1])
Item
Patient meets the criteria for inclusion
integer
C1512693 (UMLS CUI [1])
Code List
Patient meets the criteria for inclusion
CL Item
Yes (1)
CL Item
No (0)
Item
Written informed consent obtained?
integer
C0021430 (UMLS CUI [1])
Code List
Written informed consent obtained?
CL Item
Yes (1)
CL Item
No (0)
Item Group
Patient's Data
C2707520 (UMLS CUI-1)
Item
Sex
integer
C0079399 (UMLS CUI [1])
Code List
Sex
CL Item
male (1)
CL Item
female (2)
Geburtsjahr
Item
Year of birth
integer
C2826771 (UMLS CUI [1])
geoesse
Item
Size (cm)
integer
C0005890 (UMLS CUI [1])
Gewicht
Item
Body weight (kg)
float
C0005910 (UMLS CUI [1])
Item Group
Multiple Sclerosis specific information
C0026769 (UMLS CUI-1)
Datum MS-Symptomatik
Item
Date of first symptoms of MS: month/year
date
C0574845 (UMLS CUI [1,1])
C0026769 (UMLS CUI [1,2])
Item
Unknown
integer
C0574845 (UMLS CUI [1,1])
C0026769 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
Code List
Unknown
CL Item
Yes (1)
diagdat
Item
MS diagnosis date: month/year
date
C2316983 (UMLS CUI [1,1])
C0026769 (UMLS CUI [1,2])
Item
Unknown
integer
C2316983 (UMLS CUI [1,1])
C0439673 (UMLS CUI [1,2])
C0026769 (UMLS CUI [1,3])
Code List
Unknown
CL Item
Yes (1)
Item
Clinical Course of multiple sclerosis
integer
C0449259 (UMLS CUI [1,1])
C0026769 (UMLS CUI [1,2])
Code List
Clinical Course of multiple sclerosis
CL Item
not clearly attributable (-1)
(Comment:en)
CL Item
Clinically isolated syndrome (CIS) (1)
C2350037 (UMLS CUI-1)
(Comment:en)
CL Item
Relapsing-remitting MS (RRMS) (2)
C0751967 (UMLS CUI-1)
(Comment:en)
CL Item
Secondary progressive MS (SPMS) (3)
C0751965 (UMLS CUI-1)
(Comment:en)
CL Item
Primary progressive MS (PPMS) (4)
C0751964 (UMLS CUI-1)
(Comment:en)
CL Item
Others (5)
C0026769 (UMLS CUI-1)
C0449259 (UMLS CUI-2)
C0205394 (UMLS CUI-3)
(Comment:en)
Andere Verlaufsform
Item
Other clinical course?
text
C0449259 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C0026769 (UMLS CUI [1,3])
Item
Number of flares in the last 24 months
integer
C0035020 (UMLS CUI [1,1])
C3846158 (UMLS CUI [1,2])
Code List
Number of flares in the last 24 months
CL Item
0 (0)
CL Item
1 (1)
CL Item
2 (2)
CL Item
3 (3)
CL Item
4 (4)
CL Item
5 (5)
CL Item
6 (6)
CL Item
7 (7)
CL Item
8 (8)
CL Item
9 (9)
CL Item
10 (10)
CL Item
> 10 (11)
Item
Current flare?
integer
C0856120 (UMLS CUI [1])
C0035020 (UMLS CUI [2])
Code List
Current flare?
CL Item
Yes (1)
CL Item
No (0)
Item Group
EDSS-Score 12 month ago
C3830336 (UMLS CUI-1)
C3898100 (UMLS CUI-2)
EDSS vor 12
Item
EDSS score
float
C3830336 (UMLS CUI [1,1])
C3898100 (UMLS CUI [1,2])
Item
Unknown
integer
C3830336 (UMLS CUI [1,1])
C3898100 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
Code List
Unknown
CL Item
Yes (1)
Item Group
Today's scores for functional systems
C3830336 (UMLS CUI-1)
Heutiger EDSS
Item
Today's EDSS
float
C3830336 (UMLS CUI [1])
Item
Unknown / not obtained
integer
C3830336 (UMLS CUI [1,1])
C0439673 (UMLS CUI [1,2])
Code List
Unknown / not obtained
CL Item
Yes (1)
Pyramidal
Item
Pyramidal
integer
C3829393 (UMLS CUI [1])
Sensibilität
Item
Sensitivity
integer
C3829391 (UMLS CUI [1])
Zerebral
Item
Cerebral
integer
C3829397 (UMLS CUI [1])
Kleinhirn
Item
Cerebellum
integer
C3829398 (UMLS CUI [1])
BlaseMastdarm
Item
Bowel and Bladder Functions
integer
C3829400 (UMLS CUI [1])
Gehfähigkeit
Item
Ability to walk
integer
C3829396 (UMLS CUI [1,1])
C0559964 (UMLS CUI [1,2])
Hirnstamm
Item
Brain stem
integer
C3829399 (UMLS CUI [1])
Visuell
Item
Visual
integer
C3827261 (UMLS CUI [1])
Score
Item
Sum
float
C3830336 (UMLS CUI [1])
Item Group
Previous disease-modifying MS-Medication
C2114510 (UMLS CUI-1)
Item
Was a disease-modifying MS therapy previously conducted?
integer
C2114510 (UMLS CUI [1,1])
C0026769 (UMLS CUI [1,2])
Code List
Was a disease-modifying MS therapy previously conducted?
CL Item
Yes (1)
CL Item
No, de novo therapy (please go to next field) (99)
Item
Active ingredient
text
C2114510 (UMLS CUI [1,1])
C0026769 (UMLS CUI [1,2])
Code List
Active ingredient
CL Item
Alemtuzumab (Lemtrada) (22)
C0383429 (UMLS CUI-1)
CL Item
Azathioprine (2)
C0004482 (UMLS CUI-1)
CL Item
Cyclophosphamide (4)
C0010583 (UMLS CUI-1)
CL Item
Fingolimod (Gilenya) (18)
C1699926 (UMLS CUI-1)
CL Item
Fumarate (BG-12; Tecfidera) (24)
C0058218 (UMLS CUI-1)
CL Item
COPAXONE (Copaxone) (6)
C0289884 (UMLS CUI-1)
CL Item
Immune Globulins (7)
C0021027 (UMLS CUI-1)
CL Item
Interferon ß-1A (Avonex) (19)
C0254119 (UMLS CUI-1)
C0021492 (UMLS CUI-2)
CL Item
Interferon ß-1A SC (Rebif 22 µg, Rebif 44 µg) (20)
C0254119 (UMLS CUI-1)
CL Item
Interferon ß 1SC (Betaseron, Extavia) (21)
C0244713 (UMLS CUI-1)
CL Item
* Medication from a MS study (8)
C0013175 (UMLS CUI-1)
C0013227 (UMLS CUI-2)
CL Item
Methotrexate (9)
C0025677 (UMLS CUI-1)
CL Item
Mitoxantrone (10)
C0026259 (UMLS CUI-1)
CL Item
Natalizumab (Tysabri) (11)
C1172734 (UMLS CUI-1)
CL Item
Rituximab (14)
C0393022 (UMLS CUI-1)
CL Item
Teriflunomide (Aubagio) (23)
C1718383 (UMLS CUI-1)
CL Item
Cortisone (25)
C0010137 (UMLS CUI-1)
CL Item
Others... (99)
C1115771 (UMLS CUI-1)
Wirkstoff anderer
Item
other active ingredient
text
C2114510 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C0026769 (UMLS CUI [1,3])
Wirkstoff Beginn
Item
Start: Month/year
date
C3173309 (UMLS CUI [1,1])
C2114510 (UMLS CUI [1,2])
C0026769 (UMLS CUI [1,3])
Wirkstoff Ende
Item
End: Month
date
C1531784 (UMLS CUI [1,1])
C2114510 (UMLS CUI [1,2])
C0026769 (UMLS CUI [1,3])
Item
Main reason for stopping the therapy
integer
C0850893 (UMLS CUI [1,1])
C0566251 (UMLS CUI [1,2])
C0026769 (UMLS CUI [1,3])
Code List
Main reason for stopping the therapy
CL Item
Side effects (1)
C0559546 (UMLS CUI-1)
(Comment:en)
CL Item
Lack effectiveness (2)
C0235828 (UMLS CUI-1)
(Comment:en)
CL Item
Another reason (99)
C3840932 (UMLS CUI-1)
C0850893 (UMLS CUI-2)
(Comment:en)
Text Anderer Grund
Item
If other, please indicate the reason
text
C3840932 (UMLS CUI [1,1])
C0850893 (UMLS CUI [1,2])
C0026769 (UMLS CUI [1,3])
Item Group
Current MS therapy
C2827774 (UMLS CUI-1)
Item
Active ingredient
text
C2827774 (UMLS CUI [1,1])
C0026769 (UMLS CUI [1,2])
Code List
Active ingredient
CL Item
Alemtuzumab (Lemtrada) (22)
C0383429 (UMLS CUI-1)
CL Item
Azathioprine (2)
C0004482 (UMLS CUI-1)
CL Item
Cyclophosphamide (4)
C0010583 (UMLS CUI-1)
CL Item
Fingolimod (Gilenya) (18)
C1699926 (UMLS CUI-1)
CL Item
Fumarate (BG-12; Tecfidera) (24)
C0058218 (UMLS CUI-1)
CL Item
COPAXONE (Copaxone) (6)
C0289884 (UMLS CUI-1)
CL Item
Immune Globulins (7)
C0021027 (UMLS CUI-1)
CL Item
Interferon ß-1A (Avonex) (19)
C0254119 (UMLS CUI-1)
C0021492 (UMLS CUI-2)
CL Item
Interferon ß-1A SC (Rebif 22 µg, Rebif 44 µg) (20)
C0254119 (UMLS CUI-1)
CL Item
Interferon ß 1SC (Betaseron, Extavia) (21)
C0244713 (UMLS CUI-1)
CL Item
* Medication from a MS study (8)
C0013175 (UMLS CUI-1)
C0013227 (UMLS CUI-2)
CL Item
Methotrexate (9)
C0025677 (UMLS CUI-1)
CL Item
Mitoxantrone (10)
C0026259 (UMLS CUI-1)
CL Item
Natalizumab (Tysabri) (11)
C1172734 (UMLS CUI-1)
CL Item
Rituximab (14)
C0393022 (UMLS CUI-1)
CL Item
Teriflunomide (Aubagio) (23)
C1718383 (UMLS CUI-1)
CL Item
Cortisone (25)
C0010137 (UMLS CUI-1)
CL Item
Others... (99)
C1115771 (UMLS CUI-1)
curth1a
Item
other active ingredient
text
C2827774 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C0026769 (UMLS CUI [1,3])
curth1ab
Item
Start: Month/year
date
C3173309 (UMLS CUI [1,1])
C2827774 (UMLS CUI [1,2])
C0026769 (UMLS CUI [1,3])
Item
Regimen
integer
C1276413 (UMLS CUI [1,1])
C2827774 (UMLS CUI [1,2])
C0026769 (UMLS CUI [1,3])
Code List
Regimen
CL Item
Standard (1)
CL Item
Others (99)
andere
Item
Please specify the dose and type of administration
text
C0001555 (UMLS CUI [1,1])
C2827774 (UMLS CUI [1,2])
C0026769 (UMLS CUI [1,3])
Item Group
Other diagnoses
C0332138 (UMLS CUI-1)
WeitereErkr
Item
Has any other of the following diagnoses been diagnosed?
boolean
C0332138 (UMLS CUI [1])
Item Group
Heart / cardiovascular disease
C0007222 (UMLS CUI-1)
Item
Heart / cardiovascular disease
integer
C0007222 (UMLS CUI [1])
Code List
Heart / cardiovascular disease
CL Item
NA (1)
Item
Which disease has been diagnosed?
integer
C0007222 (UMLS CUI [1,1])
C0457464 (UMLS CUI [1,2])
Code List
Which disease has been diagnosed?
CL Item
High blood pressure (02)
C0020538 (UMLS CUI-1)
CL Item
Heart failure/insufficiency (03)
C0392173 (UMLS CUI-1)
CL Item
Heart rhythm disorder (04)
C0003811 (UMLS CUI-1)
CL Item
Heart attack (05)
C0027051 (UMLS CUI-1)
CL Item
CHD / Angina Pectoris (06)
C0010068 (UMLS CUI-1)
CL Item
Vein thrombosis (07)
C0587220 (UMLS CUI-1)
CL Item
Pulmonary embolism (08)
C0034065 (UMLS CUI-1)
Kreislauferkrankungen: Monat/Jahr
Item
Month/year
date
C0007222 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
Item
Date unknown
integer
C0007222 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
Code List
Date unknown
CL Item
Yes (1)
Item
Current drug treatment
integer
C0007222 (UMLS CUI [1,1])
C2827774 (UMLS CUI [1,2])
Code List
Current drug treatment
CL Item
Yes (1)
CL Item
No (0)
Item Group
Metabolic diseases
C0025517 (UMLS CUI-1)
Item
Metabolic diseases
integer
C0025517 (UMLS CUI [1])
Code List
Metabolic diseases
CL Item
NA (1)
Item
Which disease has been diagnosed?
integer
C0025517 (UMLS CUI [1,1])
C0457464 (UMLS CUI [1,2])
Code List
Which disease has been diagnosed?
CL Item
Diabetes mellitus (11)
C0011849 (UMLS CUI-1)
CL Item
Thyroid under or overactive (12)
C0040128 (UMLS CUI-1)
Stoffwechsel: Monat/Jahr
Item
Month/year
date
C0025517 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
Item
Date unknown
integer
C0025517 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
Code List
Date unknown
CL Item
Yes (1)
Item
Current drug treatment
integer
C0025517 (UMLS CUI [1,1])
C2827774 (UMLS CUI [1,2])
Code List
Current drug treatment
CL Item
Yes (1)
CL Item
No (0)
Item Group
Infectious diseases
C0009450 (UMLS CUI-1)
Item
Infectious diseases
integer
C0009450 (UMLS CUI [1])
Code List
Infectious diseases
CL Item
NA (1)
Item
Which disease has been diagnosed?
integer
C0009450 (UMLS CUI [1,1])
C0457464 (UMLS CUI [1,2])
Code List
Which disease has been diagnosed?
CL Item
Hepatitis B or C (21)
C0019163 (UMLS CUI-1)
C0019196 (UMLS CUI-3)
CL Item
HIV infection (22)
C0019693 (UMLS CUI-1)
CL Item
Tuberculosis (23)
C0041296 (UMLS CUI-1)
CL Item
Opportunistic infections (24)
C0029118 (UMLS CUI-1)
CL Item
Herpes infection (25)
C0019372 (UMLS CUI-1)
CL Item
PML (26)
C0023524 (UMLS CUI-1)
CL Item
Lung inflammation (27)
C0032285 (UMLS CUI-1)
Welche opportunistische Infektion
Item
If Yes, what opportunistic infection
text
C0029118 (UMLS CUI [1])
Ort der Herpes-Infektion
Item
Site of infection
text
C0019372 (UMLS CUI [1,1])
C0475264 (UMLS CUI [1,2])
Infektion: Monat/Jahr
Item
Month/year
date
C0009450 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
Item
Date unknown
integer
C0009450 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
Code List
Date unknown
CL Item
Yes (1)
Item
Current drug treatment
integer
C0009450 (UMLS CUI [1,1])
C2827774 (UMLS CUI [1,2])
Code List
Current drug treatment
CL Item
Yes (1)
CL Item
No (0)
Item Group
Gastrointestinal diseases
C0017178 (UMLS CUI-1)
Item
Gastrointestinal diseases
integer
C0017178 (UMLS CUI [1])
Code List
Gastrointestinal diseases
CL Item
NA (1)
Item
Which disease has been diagnosed?
integer
C0017178 (UMLS CUI [1,1])
C0457464 (UMLS CUI [1,2])
Code List
Which disease has been diagnosed?
CL Item
Inflammation of the pancreas (31)
C3889003 (UMLS CUI-1)
CL Item
Cirrhosis of the liver (32)
C0023890 (UMLS CUI-1)
CL Item
Crohn's disease (33)
C0010346 (UMLS CUI-1)
CL Item
Ulcerative colitis (34)
C0009324 (UMLS CUI-1)
Gastro: Monat/Jahr
Item
Month/year
date
C0017178 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
Item
Date unknown
integer
C0017178 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
Code List
Date unknown
CL Item
Yes (1)
Item
Current drug treatment
integer
C0017178 (UMLS CUI [1,1])
C2827774 (UMLS CUI [1,2])
Code List
Current drug treatment
CL Item
Yes (1)
CL Item
No (0)
Item Group
Neurological / psychiatric disorders
C0027765 (UMLS CUI-1)
C0004936 (UMLS CUI-3)
Item
Neurological / psychiatric disorders
integer
C0027765 (UMLS CUI [1])
C0004936 (UMLS CUI [2])
Code List
Neurological / psychiatric disorders
CL Item
NA (1)
Item
Which disease has been diagnosed?
integer
C0027765 (UMLS CUI [1,1])
C0457464 (UMLS CUI [1,2])
C0004936 (UMLS CUI [2,1])
C0457464 (UMLS CUI [2,2])
Code List
Which disease has been diagnosed?
CL Item
Epileptic seizures (41)
C0036572 (UMLS CUI-1)
CL Item
Depression (42)
C0011581 (UMLS CUI-1)
CL Item
Angsstörungen, panic attacks (43)
C0497330 (UMLS CUI-1)
CL Item
Migraine / headache (44)
C0149931 (UMLS CUI-1)
CL Item
Anorexia (45)
C0003123 (UMLS CUI-1)
Neuro: Monat/Jahr
Item
Month/year
date
C0027765 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
C0004936 (UMLS CUI [2,1])
C0011008 (UMLS CUI [2,2])
Item
Date unknown
integer
C0027765 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
C0004936 (UMLS CUI [2,1])
C0011008 (UMLS CUI [2,2])
C0439673 (UMLS CUI [2,3])
Code List
Date unknown
CL Item
Yes (1)
Item
Current drug treatment
integer
C0027765 (UMLS CUI [1,1])
C2827774 (UMLS CUI [1,2])
C0004936 (UMLS CUI [2,1])
C2827774 (UMLS CUI [2,2])
Code List
Current drug treatment
CL Item
Yes (1)
CL Item
No (0)
Item Group
Allergies
C0020517 (UMLS CUI-1)
Item
Allergies
integer
C0020517 (UMLS CUI [1])
Code List
Allergies
CL Item
NA (1)
Item
Which disease has been diagnosed?
integer
C0020517 (UMLS CUI [1,1])
C0457464 (UMLS CUI [1,2])
Code List
Which disease has been diagnosed?
CL Item
Drug allergy (51)
C0013182 (UMLS CUI-1)
CL Item
House dust / pollen (52)
C0339808 (UMLS CUI-1)
C1548336 (UMLS CUI-3)
CL Item
Food (53)
C0016470 (UMLS CUI-1)
CL Item
Nickel / fragrances (54)
C1690547 (UMLS CUI-1)
C0577618 (UMLS CUI-3)
CL Item
Insect bites (55)
C0854051 (UMLS CUI-1)
Medikamentenallergien
Item
Which drug?
text
C0013182 (UMLS CUI [1,1])
C2360065 (UMLS CUI [1,2])
Allergien: Monat/Jahr
Item
Month/year
date
C0020517 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
Item
Date unknown
integer
C0020517 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
Code List
Date unknown
CL Item
Yes (1)
Item
Current drug treatment
integer
C0020517 (UMLS CUI [1,1])
C2827774 (UMLS CUI [1,2])
Code List
Current drug treatment
CL Item
Yes (1)
CL Item
No (0)
Item Group
Genitourinary Disorders
C0080276 (UMLS CUI-1)
Item
Genitourinary Disorders
integer
C0080276 (UMLS CUI [1])
Code List
Genitourinary Disorders
CL Item
NA (1)
Item
Which disease has been diagnosed?
integer
C0080276 (UMLS CUI [1,1])
C0457464 (UMLS CUI [1,2])
Code List
Which disease has been diagnosed?
CL Item
Recurrent urinary tract infections (61)
C0262655 (UMLS CUI-1)
CL Item
Renal impairment (62)
C0151746 (UMLS CUI-1)
CL Item
Other urological diseases (63)
C0080276 (UMLS CUI-1)
Uro: Monat/Jahr
Item
Month/year
date
C0080276 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
Item
Date unknown
integer
C0080276 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
Code List
Date unknown
CL Item
Yes (1)
Item
Current drug treatment
integer
C0080276 (UMLS CUI [1,1])
C2827774 (UMLS CUI [1,2])
Code List
Current drug treatment
CL Item
Yes (1)
CL Item
No (0)
Item Group
Auto-immune diseases
C0004364 (UMLS CUI-1)
Item
Auto-immune diseases
integer
C0004364 (UMLS CUI [1])
Code List
Auto-immune diseases
CL Item
NA (1)
Item
Which disease has been diagnosed?
integer
C0004364 (UMLS CUI [1,1])
C0457464 (UMLS CUI [1,2])
Code List
Which disease has been diagnosed?
CL Item
Myasthenia gravis (71)
C0026896 (UMLS CUI-1)
CL Item
Autoimmune thyroid disease (72)
C0178468 (UMLS CUI-1)
CL Item
Systemic Lupus Erythematosus (73)
C0024141 (UMLS CUI-1)
CL Item
Psoriasis (74)
C0033860 (UMLS CUI-1)
Autoimmun: Monat/Jahr
Item
Month/year
date
C0004364 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
Item
Date unknown
integer
C0004364 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
Code List
Date unknown
CL Item
Yes (1)
Item
Current drug treatment
integer
C0004364 (UMLS CUI [1,1])
C2827774 (UMLS CUI [1,2])
Code List
Current drug treatment
CL Item
Yes (1)
CL Item
No (0)
Item Group
Blood Count / laboratory
C0018939 (UMLS CUI-1)
Item
Blood Count / laboratory
integer
C0018939 (UMLS CUI [1])
Code List
Blood Count / laboratory
CL Item
NA (1)
Item
Which disease has been diagnosed?
integer
C0018939 (UMLS CUI [1,1])
C0457464 (UMLS CUI [1,2])
Code List
Which disease has been diagnosed?
CL Item
Anemia (81)
C0002871 (UMLS CUI-1)
CL Item
Lymphopenia (82)
C0024312 (UMLS CUI-1)
CL Item
Leukopenia (83)
C0023530 (UMLS CUI-1)
CL Item
Neutropenia (84)
C0027947 (UMLS CUI-1)
CL Item
Coagulation disorders (85)
C0005779 (UMLS CUI-1)
CL Item
Myelodysplastic syndrome (86)
C3463824 (UMLS CUI-1)
CL Item
Saliency in Lebertest(s) (87)
C0438237 (UMLS CUI-1)
CL Item
Saliency in Nierentest(s) (88)
C0236151 (UMLS CUI-1)
BlutLab: Monat/Jahr
Item
Month/year
date
C0018939 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
Item
Date unknown
integer
C0018939 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
Code List
Date unknown
CL Item
Yes (1)
Item
Current drug treatment
integer
C0018939 (UMLS CUI [1,1])
C2827774 (UMLS CUI [1,2])
Code List
Current drug treatment
CL Item
Yes (1)
CL Item
No (0)
Item Group
General Symptoms
C0159028 (UMLS CUI-1)
Item
General symptoms
integer
C0159028 (UMLS CUI [1])
Code List
General symptoms
CL Item
NA (1)
Item
Which symptom was diagnosed?
integer
C0159028 (UMLS CUI [1,1])
C0457464 (UMLS CUI [1,2])
Code List
Which symptom was diagnosed?
CL Item
Hair loss (91)
C0002170 (UMLS CUI-1)
CL Item
Skin rash (92)
C0015230 (UMLS CUI-1)
CL Item
local symptoms with medications (93)
C0853813 (UMLS CUI-1)
C0877248 (UMLS CUI-2)
CL Item
Retinopathy, macular edema (94)
C0035309 (UMLS CUI-1)
C0271051 (UMLS CUI-3)
CL Item
Joint pain (95)
C0003862 (UMLS CUI-1)
CL Item
Weight loss or gain (96)
C0005911 (UMLS CUI-1)
AllgemSympt: Monat/Jahr
Item
Month/year
date
C0159028 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
Item
Date unknown
integer
C0159028 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
Code List
Date unknown
CL Item
Yes (1)
Item
Current drug treatment
integer
C0159028 (UMLS CUI [1,1])
C2827774 (UMLS CUI [1,2])
Code List
Current drug treatment
CL Item
Yes (1)
CL Item
No (0)
Item Group
Operation
C0543467 (UMLS CUI-1)
Item
Operation
integer
C0543467 (UMLS CUI [1])
Code List
Operation
CL Item
NA (1)
Operation
Item
Which operations?
text
C0679638 (UMLS CUI [1])
Operation: Monat/Jahr
Item
Month/year
date
C0543467 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
Item
Date unknown
integer
C0543467 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
C0439673 (UMLS CUI [1,3])
Code List
Date unknown
CL Item
Yes (1)
Item
Current drug treatment
integer
C0543467 (UMLS CUI [1,1])
C2827774 (UMLS CUI [1,2])
Code List
Current drug treatment
CL Item
Yes (1)
CL Item
No (0)
Item Group
Cancer
C0006826 (UMLS CUI-1)
Item
Cancer
integer
C0006826 (UMLS CUI [1])
CL Item
NA (1)
Art von Krebs
Item
What kind of cancer
text
C0006826 (UMLS CUI [1,1])
C0457464 (UMLS CUI [1,2])
Krebs: Monat/Jahr
Item
Month/year
date
C0006826 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
Item Group
Cancer Treatment?
C0920425 (UMLS CUI-1)
Item
Operation
integer
C0543467 (UMLS CUI [1,1])
C0920425 (UMLS CUI [1,2])
Code List
Operation
CL Item
Yes (1)
CL Item
No (0)
Item
Radiation
integer
C1522449 (UMLS CUI [1,1])
C0920425 (UMLS CUI [1,2])
Code List
Radiation
CL Item
Yes (1)
CL Item
No (0)
Item
Chemotherapy
integer
C3665472 (UMLS CUI [1,1])
C0920425 (UMLS CUI [1,2])
Code List
Chemotherapy
CL Item
Yes (1)
CL Item
No (0)
Substanzen
Item
If yes, please specify substances chemotherapy
text
C0729502 (UMLS CUI [1,1])
C0920425 (UMLS CUI [1,2])
Item
not known
integer
C0729502 (UMLS CUI [1,1])
C0439673 (UMLS CUI [1,2])
C0920425 (UMLS CUI [1,3])
Code List
not known
CL Item
Yes (1)
Item Group
Other diseases?
C0332138 (UMLS CUI-1)
C0205394 (UMLS CUI-2)
Item
Other diseases
integer
C0332138 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
Code List
Other diseases
CL Item
NA (1)
Andere
Item
What other disease?
text
C0332138 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C0457464 (UMLS CUI [1,3])
Andere: Monat/Jahr
Item
Month/year
date
C0332138 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C0011008 (UMLS CUI [1,3])
Item
Date unknown
integer
C0332138 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C0011008 (UMLS CUI [1,3])
C0439673 (UMLS CUI [1,4])
Code List
Date unknown
CL Item
Yes (1)
Item
Current drug treatment
integer
C0332138 (UMLS CUI [1,1])
C0205394 (UMLS CUI [1,2])
C2827774 (UMLS CUI [1,3])
Code List
Current drug treatment
CL Item
Yes (1)
CL Item
No (0)
Item Group
None of the mentioned secondary diagnoses known
Item
Applicable
integer
C0549184 (UMLS CUI [1])
Code List
Applicable
CL Item
Yes (1)
Item Group
Pregnancy
C0032961 (UMLS CUI-1)
Item
Currently pregnant?
integer
C0549206 (UMLS CUI [1])
Code List
Currently pregnant?
CL Item
No (0)
CL Item
Yes (1)
Item Group
Biologic Material (for example blood)
C0370003 (UMLS CUI-1)
Probennummer
Item
Sample No.
text
C0370003 (UMLS CUI [1,1])
C1300638 (UMLS CUI [1,2])
Zusatz
Item
Additional (currently disabled)
text
C0947611 (UMLS CUI [1])