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No (No)

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Unknown (Unknown)

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Yes (Yes)

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Fully Active, Able To Carry On All Pre-disease Performance Without Restriction. (0)

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Restricted In Physically Strenuous Activity But Ambulatory And Able To Carry Out Work Of A Light Or Sedentary Nature, E.g., Light Housework, Office Work. (1)

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Ambulatory And Capable Of All Selfcare But Unable To Carry Out Any Work Activities. Up And About More Than 50% Of Waking Hours. (2)

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Capable Of Only Limited Selfcare, Confined To Bed Or Chair More Than 50% Of Waking Hours. (3)

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Completely Disabled. Cannot Carry On Any Selfcare. Totally Confined To Bed Or Chair. (4)

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No (No)

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Unknown (Unknown)

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Yes (Yes)

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Weight Loss Of 10% Or More Within The Previous 6 Months (Weight loss of 10% or more within the previous 6 months)

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Extreme Fatigue (Extreme fatigue)

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Fevers Of Greater Than 100.5 Degrees F For 2 Weeks Without Evidence Of Infection (Fevers of greater than 100.5 degrees F for 2 weeks without evidence of infection)

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Drenching Night Sweats More Than 3 Times Per Week Without Evidence Of Infection That Require The Patient To Change Clothes (Drenching night sweats more than 3 times per week without evidence of infection that require the patient to change clothes)

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Other Disease Related Symptoms (skin Infitration, Vasculitis, Pemphigus) (Other disease related symptoms (skin infitration, vasculitis, pemphigus))

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Evidence Of Progressive Marrow Failure As Manifested By Hemoglobin <11 G/dl In The Absence Of Autoimmune Hemolytic Anemia (Evidence of progressive marrow failure as manifested by hemoglobin <11 g/dL in the absence of autoimmune hemolytic anemia)

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Evidence Of Progressive Marrow Failure As Manifested By Thrombocytopenia <100 X 10^12 /l In The Absence Of Idiopathic Thrombocytopenia Purpura (Evidence of progressive marrow failure as manifested by thrombocytopenia <100 x 10^12 /L in the absence of idiopathic thrombocytopenia purpura)

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Evidence Of Progressive Marrow Failure As Manifested By Autoimmune Anemia Or Thrombocytopenia Poorly Responsive To Corticosteroid Therapy (Evidence of progressive marrow failure as manifested by autoimmune anemia or thrombocytopenia poorly responsive to corticosteroid therapy)

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Evidence Of Progressive Marrow Failure As Manifested By Massive (i.e., >6 Cm Below The Left Costal Margin) Or Progressive Splenomegaly That Is Causing Pain Or Significantly Early Satiety (Evidence of progressive marrow failure as manifested by massive (i.e., >6 cm below the left costal margin) or progressive splenomegaly that is causing pain or significantly early satiety)

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Evidence Of Progressive Marrow Failure As Manifested By Massive Nodes Or Clusters (i.e., >10 Cm In Longest Diameter) Or Progressive Lymphadenopathy That Is Causing Pain Or Significant Disfigurement (Evidence of progressive marrow failure as manifested by massive nodes or clusters (i.e., >10 cm in longest diameter) or progressive lymphadenopathy that is causing pain or significant disfigurement)

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Evidence Of Progressive Marrow Failure As Manifested By Lymphocyte Count > 300 X 10^9 /l (Evidence of progressive marrow failure as manifested by lymphocyte count > 300 x 10^9 /L)