ID

4757

Description

The investigators plan to improve the learning of motor skills by pharmacological means (dopamine), and by noninvasive brain stimulation. They will study both healthy subjects and chronic stroke patients. In addition, they want to study the mechanisms of enhanced learning, on the molecular and the systems level. Condition: Stroke Intervention: drug dopamine Phase 4 See http://clinicaltrials.gov/ct2/show/record/NCT00126087

Link

http://clinicaltrials.gov/ct2/show/record/NCT00126087

Keywords

Versions (2)
  1. 11/18/11 11/18/11 -
  2. 3/26/14 3/26/14 - Martin Dugas
Uploaded on

March 26, 2014

DOI

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License

Creative Commons BY 4.0
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Eligibility NCT00126087 Stroke

English

Eligibility Stroke NCT00126087

1 forms  
  1. StudyEvent: Eligibility
    1. Eligibility Stroke NCT00126087
Inclusion healthy volunteers
Description

Inclusion healthy volunteers

Alias
UMLS CUI-1
C1512693
UMLS CUI-2
C1708335
18 Years to 80 Years
Description

Age

Data type

boolean

Alias
UMLS CUI-1
C0001779
Normal neurological examination
Description

Neurological examination normal

Data type

boolean

Alias
UMLS CUI-1
C1112287
Mini Mental State Examination of more than 27
Description

Mini-mental state examination

Data type

integer

Alias
UMLS CUI-1
C0451306
Right Handedness
Description

Handedness

Data type

boolean

Alias
UMLS CUI-1
C0023114
Inclusion patients
Description

Inclusion patients

Alias
UMLS CUI-1
C1512693
Cortical or subcortical stroke with an initial severe hemiparesis Medical Research Council (MRC) scale less than 2 that has recovered to a degree that patients are able to perform the proposed task (in general more than MRC 4.5, with low spasticity, work in progress on motor learning in stroke patients)
Description

Stroke

Data type

boolean

Alias
UMLS CUI-1
C0038454
At least 1 year post-stroke
Description

post-stroke

Data type

boolean

Mini Mental State Examination more than 27
Description

Mini-mental state examination

Data type

integer

Alias
UMLS CUI-1
C0451306
Right Handedness
Description

Handedness

Data type

boolean

Alias
UMLS CUI-1
C0023114
Exclusion Criteria healthy volunteers and stroke patients
Description

Exclusion Criteria healthy volunteers and stroke patients

Alias
UMLS CUI-1
C0680251
No antipsychotic, antidepressant drugs, and drugs affecting the dopaminergic system
Description

Medication

Data type

boolean

Alias
UMLS CUI-1
C0013227
UMLS CUI-2
C0040615
UMLS CUI-3
C0003289
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Similar models

Eligibility Stroke NCT00126087

1 forms
  1. StudyEvent: Eligibility
    1. Eligibility Stroke NCT00126087
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
Inclusion healthy volunteers
C1512693 (UMLS CUI-1)
C1708335 (UMLS CUI-2)
Age
Item
18 Years to 80 Years
boolean
C0001779 (UMLS CUI-1)
Neurological examination normal
Item
Normal neurological examination
boolean
C1112287 (UMLS CUI-1)
Mini-mental state examination
Item
Mini Mental State Examination of more than 27
integer
C0451306 (UMLS CUI-1)
Handedness
Item
Right Handedness
boolean
C0023114 (UMLS CUI-1)
Item Group
Inclusion patients
C1512693 (UMLS CUI-1)
Stroke
Item
Cortical or subcortical stroke with an initial severe hemiparesis Medical Research Council (MRC) scale less than 2 that has recovered to a degree that patients are able to perform the proposed task (in general more than MRC 4.5, with low spasticity, work in progress on motor learning in stroke patients)
boolean
C0038454 (UMLS CUI-1)
post-stroke
Item
At least 1 year post-stroke
boolean
Mini-mental state examination
Item
Mini Mental State Examination more than 27
integer
C0451306 (UMLS CUI-1)
Handedness
Item
Right Handedness
boolean
C0023114 (UMLS CUI-1)
Item Group
Exclusion Criteria healthy volunteers and stroke patients
C0680251 (UMLS CUI-1)
Medication
Item
No antipsychotic, antidepressant drugs, and drugs affecting the dopaminergic system
boolean
C0013227 (UMLS CUI-1)
C0040615 (UMLS CUI-2)
C0003289 (UMLS CUI-3)
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