ID
45999
Beschreibung
Principal Investigator: Esteban Burchard, MD, MPH, University of California, San Francisco, CA, USA MeSH: Lung Diseases https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000921 This is a parallel case-control pharmacogenetic study of bronchodilator drug response among African American children with and without asthma. Each participant had spirometry measured using the KoKo PFT System. Asthmatic participants were administered with 4 puffs of HFA Albuterol. Healthy participants were given a baseline spirometry test. The overall goal is to identify genetic factors which are predictive of drug response in children with asthma. The principal tools include a questionnaire and biological specimen collection. Participants were 8-21 years old at time of recruitment. Children with asthma have physician-diagnosed asthma, symptoms and medications.
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Versionen (1)
- 18.04.24 18.04.24 - Madita Rudolph
Rechteinhaber
Esteban Burchard, MD, MPH, University of California, San Francisco, CA, USA
Hochgeladen am
18. April 2024
DOI
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Lizenz
Creative Commons BY 4.0
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dbGaP phs000921 NHLBI TOPMed: Study of African Americans, Asthma, Genes and Environment (SAGE)
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- The subject consent data table contains subject IDs, consent group information, and subject aliases.
- This subject sample mapping data table includes a mapping of study subject IDs to sample IDs. Samples are the final preps submitted for genotyping, sequencing, and/or expression data. For example, if one patient (subject ID) gave one sample, and that sample was processed differently to generate 2 sequencing runs, there would be two rows, both using the same subject ID, but having 2 unique sample IDs. The data table also includes sample source.
- This subject phenotype table includes subject age, gender, race, BMI, affection status for asthma, smoking status, hospitalization due to asthma, steroid treatment, bronchodilator response after treatment, NO2 and PM25 air pollution measurement in lifetime average.
- This sample attributes table includes body site where sample was collected, analyte type, tumor status, sequencing center, funding source, TOPMed phase, project, and study name.
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Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- The subject consent data table contains subject IDs, consent group information, and subject aliases.
- This subject sample mapping data table includes a mapping of study subject IDs to sample IDs. Samples are the final preps submitted for genotyping, sequencing, and/or expression data. For example, if one patient (subject ID) gave one sample, and that sample was processed differently to generate 2 sequencing runs, there would be two rows, both using the same subject ID, but having 2 unique sample IDs. The data table also includes sample source.
- This subject phenotype table includes subject age, gender, race, BMI, affection status for asthma, smoking status, hospitalization due to asthma, steroid treatment, bronchodilator response after treatment, NO2 and PM25 air pollution measurement in lifetime average.
- This sample attributes table includes body site where sample was collected, analyte type, tumor status, sequencing center, funding source, TOPMed phase, project, and study name.
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