ID
45992
Description
Principal Investigator: Elad Ziv, MD, University of California, San Francisco, USA MeSH: Breast Neoplasms,Receptors, Estrogen,Receptors, Progesterone https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000912 The genome-wide association study (GWAS) includes participants enrolled into two different studies. The first study, the San Francisco Bay Area Cancer Study (SFBCS) is a population-based case-control study of breast cancer conducted in the San Francisco Bay Area and included women ages 35-79 years from three racial/ethnic groups: Non-Hispanic whites, African Americans, and Hispanics/Latinas. For the GWAS, only Hispanic/Latina women were included. Women diagnosed with invasive breast cancer between 1995 and 2002 were identified through the Greater Bay Area Cancer Registry. Controls were identified by random digit dialing and were frequency-matched to cases by age in 5 year increments and by race/ethnicity. Hispanic/Latina ethnicity was assessed by self-report. 175 Hispanic/Latina cases and 307 Hispanic/Latina controls from the SFBCS had given adequate consent and provided biospecimens that were used in the GWAS to be included in this data submission. The second study is the Northern California site of the Breast Cancer Family Registry (NC-BCFR). This population-based family study recruited breast cancer cases ages 18-64 years diagnosed from 1995-2009 that were identified through the Greater Bay Area Cancer Registry. Cases included all women at increased genetic susceptibility for breast cancer who met one or more of the following criteria: (a) being diagnosed with breast cancer at age 35 years; b) having a personal history of ovarian cancer or childhood cancer; (c) being diagnosed with two different breast cancers (bilateral breast cancers), with the first one diagnosed at age 50 years; and d) having one or more first-degree relatives with breast cancer, ovarian cancer or childhood cancer. Cases not meeting these criteria were randomly sampled and racial/ethnic minorities were oversampled. Controls were recruited by random digit dialing and were matched by 5-year age increments and by race/ethnicity. For the current GWAS only Latina/Hispanic cases and controls were included. Latina/Hispanic ethnicity was assessed by self-report. 631 Hispanic/Latina cases and 61 Hispanic/Latina controls from the NC-BCFR had given adequate consent and provided biospecimens that were used in the GWAS to be included in this data submission.
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Versions (1)
- 4/11/24 4/11/24 - Madita Rudolph
Copyright Holder
Elad Ziv, MD, University of California, San Francisco, USA
Uploaded on
April 11, 2024
DOI
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License
Creative Commons BY 4.0
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dbGaP phs000912 San Francisco Bay Area Latina Breast Cancer Study
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID, consent group, and case or control status of participants with or without breast cancer and involved in the "San Francisco Bay Area Latina Breast Cancer Study" project.
- Subject ID, sample ID, and sample use variable obtained from participants with or without breast cancer and involved in the "San Francisco Bay Area Latina Breast Cancer Study" project.
- Subject ID, case or control status, bilateral breast cancer, age at diagnosis, gender, histological type and grade at diagnosis, status of estrogen and progesterone receptor of breast tumor of participants with or without breast cancer and involved in the "San Francisco Bay Area Latina Breast Cancer Study" project.
- Sample ID, body site where sample was obtained, analyte type, genotyping center, source repository where subject originate, and subject ID used in the source repository of participants with or without breast cancer and involved in the "San Francisco Bay Area Latina Breast Cancer Study" project.
Similar models
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID, consent group, and case or control status of participants with or without breast cancer and involved in the "San Francisco Bay Area Latina Breast Cancer Study" project.
- Subject ID, sample ID, and sample use variable obtained from participants with or without breast cancer and involved in the "San Francisco Bay Area Latina Breast Cancer Study" project.
- Subject ID, case or control status, bilateral breast cancer, age at diagnosis, gender, histological type and grade at diagnosis, status of estrogen and progesterone receptor of breast tumor of participants with or without breast cancer and involved in the "San Francisco Bay Area Latina Breast Cancer Study" project.
- Sample ID, body site where sample was obtained, analyte type, genotyping center, source repository where subject originate, and subject ID used in the source repository of participants with or without breast cancer and involved in the "San Francisco Bay Area Latina Breast Cancer Study" project.
C0680251 (UMLS CUI [1,2])
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C1706256 (UMLS CUI [1,2])
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C0009932 (UMLS CUI [1,2])
C0522473 (UMLS CUI [1,3])
C2348568 (UMLS CUI [1,4])
C0021430 (UMLS CUI [1,5])
C1299582 (UMLS CUI [1,6])