ID

45984

Descripción

Principal Investigator: Gerald Nestadt, Johns Hopkins University, Baltimore, MD, USA MeSH: Obsessive-Compulsive Disorder https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000903 The OCD Collaborative Genetics Association Study Group (OCGAS) was funded by NIMH to conduct a genome-wide association study to identify disease susceptibility loci of early-onset obsessive-compulsive disorder (OCD). Collaborators at Johns Hopkins, Brown, Columbia, MGH, UCLA, and NIMH evaluated 2,000 individuals with OCD and collected DNA from these individuals and both their parents. The genotyping and analyses was performed in two stages. In the first stage 1,065 families (comprising 1406 patients with OCD and 2895 individuals in total) were genotyped on the Illumina OmniExpress GWA (SNPs) panel at the JHU SNP Center.

Link

dbGaP study=phs000903

Palabras clave

  1. 06-04-24 06-04-24 - Madita Rudolph
Titular de derechos de autor

Gerald Nestadt, Johns Hopkins University, Baltimore, MD, USA

Subido en

6 april 2024

DOI

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Licencia

Creative Commons BY 4.0

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dbGaP phs000903 OCD Collaborative Genetic Association Study (OCGAS)

Eligibility Criteria

Inclusion and exclusion criteria
Descripción

Inclusion and exclusion criteria

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0680251
Probands were required to meet DSM-IV criteria for OCD with onset of obsessions and/or compulsions before the age of 18 years.
Descripción

Elig.phs000903.v1.p1.1

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0220952
UMLS CUI [1,2]
C0028768
UMLS CUI [1,3]
C0206132
Subjects with brain disease, schizophrenia, severe mental retardation that does not permit an evaluation to characterize the psychiatric disorder, Tourette disorder (TS), or OCD occurring exclusively in the context of depression (secondary OCD) were excluded.
Descripción

Elig.phs000903.v1.p1.2

Tipo de datos

boolean

Alias
UMLS CUI [1,1]
C0680251
UMLS CUI [1,2]
C1385010
UMLS CUI [2,1]
C0680251
UMLS CUI [2,2]
C0036341
UMLS CUI [3,1]
C0680251
UMLS CUI [3,2]
C0025362
UMLS CUI [3,3]
C0205082
UMLS CUI [4,1]
C0680251
UMLS CUI [4,2]
C0040517
UMLS CUI [5,1]
C0680251
UMLS CUI [5,2]
C0028768
UMLS CUI [5,3]
C0175668
UMLS CUI [5,4]
C0011581

Similar models

Eligibility Criteria

Name
Tipo
Description | Question | Decode (Coded Value)
Tipo de datos
Alias
Item Group
Inclusion and exclusion criteria
C1512693 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
Elig.phs000903.v1.p1.1
Item
Probands were required to meet DSM-IV criteria for OCD with onset of obsessions and/or compulsions before the age of 18 years.
boolean
C0220952 (UMLS CUI [1,1])
C0028768 (UMLS CUI [1,2])
C0206132 (UMLS CUI [1,3])
Elig.phs000903.v1.p1.2
Item
Subjects with brain disease, schizophrenia, severe mental retardation that does not permit an evaluation to characterize the psychiatric disorder, Tourette disorder (TS), or OCD occurring exclusively in the context of depression (secondary OCD) were excluded.
boolean
C0680251 (UMLS CUI [1,1])
C1385010 (UMLS CUI [1,2])
C0680251 (UMLS CUI [2,1])
C0036341 (UMLS CUI [2,2])
C0680251 (UMLS CUI [3,1])
C0025362 (UMLS CUI [3,2])
C0205082 (UMLS CUI [3,3])
C0680251 (UMLS CUI [4,1])
C0040517 (UMLS CUI [4,2])
C0680251 (UMLS CUI [5,1])
C0028768 (UMLS CUI [5,2])
C0175668 (UMLS CUI [5,3])
C0011581 (UMLS CUI [5,4])

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