ID

45969

Descrição

Principal Investigator: Stacey Gabriel, PhD, Broad Institute, Boston, MA, USA MeSH: Coronary Artery Disease https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000883 The Precocious Coronary Artery Disease (PROCARDIS) study is an international, multicenter case-control study aimed at discovering the genetic contributors to premature coronary artery disease. All exome sequencing was performed at the Broad Institute of Harvard and MIT; samples sequence capture was performed using Agilent SureSelect Human All Exon Kit v2 and sequencing was performed on an Illumina HiSeq 2000 or 2500.

Link

dbGaP study=phs000883

Palavras-chave

  1. 26/03/2024 26/03/2024 - Madita Rudolph
Titular dos direitos

Stacey Gabriel, PhD, Broad Institute, Boston, MA, USA

Transferido a

26 de março de 2024

DOI

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Licença

Creative Commons BY 4.0

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dbGaP phs000883 MIGen_ExS: PROCARDIS

Eligibility Criteria

Inclusion and exclusion criteria
Descrição

Inclusion and exclusion criteria

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0680251
Cases and controls were recruited from the United Kingdom. Cases were considered eligible for the study if premature coronary artery disease was present. This was defined as myocardial infarction (MI), unstable or stable angina, or coronary revascularization that occurred before age 66. 80% of cases had a sibling with a history of MI or acute coronary syndrome before age 66. Controls were matched by age and gender and recruited from the same centers simultaneously. Controls were eligible for the study if they had no personal or sibling history of MI, unstable or stable angina, or coronary revascularization before the age of 66.
Descrição

Elig.phs000883.v1.p1.1

Tipo de dados

boolean

Alias
UMLS CUI [1,1]
C1516637
UMLS CUI [1,2]
C2348563
UMLS CUI [1,3]
C1706256
UMLS CUI [1,4]
C1867743
UMLS CUI [2,1]
C0009932
UMLS CUI [2,2]
C1708943
UMLS CUI [2,3]
C0079399
UMLS CUI [2,4]
C0001779
UMLS CUI [2,5]
C1867743
UMLS CUI [2,6]
C0549184

Similar models

Eligibility Criteria

Name
Tipo
Description | Question | Decode (Coded Value)
Tipo de dados
Alias
Item Group
Inclusion and exclusion criteria
C1512693 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
Elig.phs000883.v1.p1.1
Item
Cases and controls were recruited from the United Kingdom. Cases were considered eligible for the study if premature coronary artery disease was present. This was defined as myocardial infarction (MI), unstable or stable angina, or coronary revascularization that occurred before age 66. 80% of cases had a sibling with a history of MI or acute coronary syndrome before age 66. Controls were matched by age and gender and recruited from the same centers simultaneously. Controls were eligible for the study if they had no personal or sibling history of MI, unstable or stable angina, or coronary revascularization before the age of 66.
boolean
C1516637 (UMLS CUI [1,1])
C2348563 (UMLS CUI [1,2])
C1706256 (UMLS CUI [1,3])
C1867743 (UMLS CUI [1,4])
C0009932 (UMLS CUI [2,1])
C1708943 (UMLS CUI [2,2])
C0079399 (UMLS CUI [2,3])
C0001779 (UMLS CUI [2,4])
C1867743 (UMLS CUI [2,5])
C0549184 (UMLS CUI [2,6])

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