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ID

45967

Description

Principal Investigator: Jennifer R. Brown, Dana-Farber Cancer Institute, Broad Institute, Boston, MA, USA MeSH: Leukemia, Lymphocytic, Chronic, B-Cell https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000879 Chronic Lymphocytic Leukemia (CLL) is a hematological malignancy characterized by accumulation of CD5+CD19+ B cells in peripheral lymphoid organs, bone marrow and blood. In this study we analyze matched whole genome sequencing and RNA-seq data from CLL patients to characterize the mutational processes operative throughout tumor evolution. Source of tumor and normal DNA used is patient PBMC or B cells and saliva respectively.

Link

dbGaP study=phs000879

Keywords

  1. 3/26/24 3/26/24 - Madita Rudolph
Copyright Holder

Jennifer R. Brown, Dana-Farber Cancer Institute, Broad Institute, Boston, MA, USA

Uploaded on

March 26, 2024

DOI

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License

Creative Commons BY 4.0

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    dbGaP phs000879 DFCI Brown Lab CLL Sequencing Study

    Similar models

    Subject ID and consent groups of participants with or without chronic lymphocytic leukemia and involved in the "Dana-Farber Cancer Institute (DFCI) Brown Lab CLL Sequencing Study" project.

    Name
    Type
    Description | Question | Decode (Coded Value)
    Data type
    Alias
    Item Group
    pht005032
    C3846158 (UMLS CUI [1,1])
    SUBJID
    Item
    Subject ID
    string
    C2348585 (UMLS CUI [1,1])
    Item
    Consent group as determined by DAC
    text
    C0021430 (UMLS CUI [1,1])
    C0441833 (UMLS CUI [1,2])
    Code List
    Consent group as determined by DAC
    CL Item
    General Research Use (GRU) (1)
    C0021430 (UMLS CUI [1,1])
    C0242481 (UMLS CUI [1,2])

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