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ID

45960

Description

Principal Investigator: Javed Khan, National Institutes of Health, Bethesda, MD, USA MeSH: Neuroblastoma https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000868 Neuroblastoma is the most common extra-cranial solid tumor in children. It represents 8% to 10% of all childhood cancers. Stage 4 Neuroblastoma is characterized by its clinical heterogeneous outcome. The special category, stage 4S tumors (2-5% of all NB) are chemo-sensitive, and the patients show spontaneous regression. On the other hand, MYCN amplification (25-30% of all NB) is associated with poor outcome of neuroblastoma, thus we further categorize stage 4 neuroblastoma into MYCN non-amplified and MYCN amplified group. Here we use transcriptome sequencing to characterize the transcriptome in 29 stage 4 Neuroblastoma samples.

Lien

dbGaP study=phs000868

Mots-clés

  1. 16/03/2024 16/03/2024 - Madita Rudolph
Détendeur de droits

Javed Khan, National Institutes of Health, Bethesda, MD, USA

Téléchargé le

16 mars 2024

DOI

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Licence

Creative Commons BY 4.0

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    dbGaP phs000868 Transcriptome Sequencing of Pediatric Neuroblastoma

    This sample attributes table includes sample IDs, analyte type, tumor status, histological type, metastatic status, tumor stage and sequencing center.

    pht004590
    Description

    pht004590

    Alias
    UMLS CUI [1,1]
    C3846158
    De-identified Sample ID
    Description

    SAMPLE_ID

    Type de données

    string

    Alias
    UMLS CUI [1,1]
    C4684638
    UMLS CUI [1,2]
    C1299222
    Analyte Type
    Description

    ANALYTE_TYPE

    Type de données

    string

    Alias
    UMLS CUI [1,1]
    C4744818
    Tumor status
    Description

    IS_TUMOR

    Type de données

    text

    Alias
    UMLS CUI [1,1]
    C0475752
    Cell or tissue type or subtype of sample
    Description

    HISTOLOGICAL_TYPE

    Type de données

    string

    Alias
    UMLS CUI [1,1]
    C2347026
    UMLS CUI [1,2]
    C0007634
    UMLS CUI [1,3]
    C0332307
    UMLS CUI [2,1]
    C2347026
    UMLS CUI [2,2]
    C0007634
    UMLS CUI [2,3]
    C0449560
    UMLS CUI [3,1]
    C1292533
    UMLS CUI [3,2]
    C0332307
    UMLS CUI [4,1]
    C1292533
    UMLS CUI [4,2]
    C0449560
    Primary tumor, metastasis, or transformed cell line
    Description

    PRIMARY_METASTATIC_TUMOR

    Type de données

    string

    Alias
    UMLS CUI [1,1]
    C0677930
    UMLS CUI [2,1]
    C0027627
    UMLS CUI [3,1]
    C0007601
    Tumor stage of sample
    Description

    TUMOR_STAGE

    Type de données

    string

    Alias
    UMLS CUI [1,1]
    C1300072
    UMLS CUI [1,2]
    C0370003
    Name of the center which conducted sequencing
    Description

    SEQUENCING_CENTER

    Type de données

    string

    Alias
    UMLS CUI [1,1]
    C1301943
    UMLS CUI [1,2]
    C0565990
    UMLS CUI [1,3]
    C1561491

    Similar models

    This sample attributes table includes sample IDs, analyte type, tumor status, histological type, metastatic status, tumor stage and sequencing center.

    Name
    Type
    Description | Question | Decode (Coded Value)
    Type de données
    Alias
    Item Group
    pht004590
    C3846158 (UMLS CUI [1,1])
    SAMPLE_ID
    Item
    De-identified Sample ID
    string
    C4684638 (UMLS CUI [1,1])
    C1299222 (UMLS CUI [1,2])
    ANALYTE_TYPE
    Item
    Analyte Type
    string
    C4744818 (UMLS CUI [1,1])
    Item
    Tumor status
    text
    C0475752 (UMLS CUI [1,1])
    Code List
    Tumor status
    CL Item
    Is not a tumor (N)
    C0027651 (UMLS CUI [1,1])
    C1518422 (UMLS CUI [1,2])
    CL Item
    Is Tumor (Y)
    C0027651 (UMLS CUI [1,1])
    HISTOLOGICAL_TYPE
    Item
    Cell or tissue type or subtype of sample
    string
    C2347026 (UMLS CUI [1,1])
    C0007634 (UMLS CUI [1,2])
    C0332307 (UMLS CUI [1,3])
    C2347026 (UMLS CUI [2,1])
    C0007634 (UMLS CUI [2,2])
    C0449560 (UMLS CUI [2,3])
    C1292533 (UMLS CUI [3,1])
    C0332307 (UMLS CUI [3,2])
    C1292533 (UMLS CUI [4,1])
    C0449560 (UMLS CUI [4,2])
    PRIMARY_METASTATIC_TUMOR
    Item
    Primary tumor, metastasis, or transformed cell line
    string
    C0677930 (UMLS CUI [1,1])
    C0027627 (UMLS CUI [2,1])
    C0007601 (UMLS CUI [3,1])
    TUMOR_STAGE
    Item
    Tumor stage of sample
    string
    C1300072 (UMLS CUI [1,1])
    C0370003 (UMLS CUI [1,2])
    SEQUENCING_CENTER
    Item
    Name of the center which conducted sequencing
    string
    C1301943 (UMLS CUI [1,1])
    C0565990 (UMLS CUI [1,2])
    C1561491 (UMLS CUI [1,3])

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