ID

45960

Descripción

Principal Investigator: Javed Khan, National Institutes of Health, Bethesda, MD, USA MeSH: Neuroblastoma https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000868 Neuroblastoma is the most common extra-cranial solid tumor in children. It represents 8% to 10% of all childhood cancers. Stage 4 Neuroblastoma is characterized by its clinical heterogeneous outcome. The special category, stage 4S tumors (2-5% of all NB) are chemo-sensitive, and the patients show spontaneous regression. On the other hand, MYCN amplification (25-30% of all NB) is associated with poor outcome of neuroblastoma, thus we further categorize stage 4 neuroblastoma into MYCN non-amplified and MYCN amplified group. Here we use transcriptome sequencing to characterize the transcriptome in 29 stage 4 Neuroblastoma samples.

Link

dbGaP study=phs000868

Palabras clave

  1. 16/3/24 16/3/24 - Madita Rudolph
Titular de derechos de autor

Javed Khan, National Institutes of Health, Bethesda, MD, USA

Subido en

16 de marzo de 2024

DOI

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Licencia

Creative Commons BY 4.0

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dbGaP phs000868 Transcriptome Sequencing of Pediatric Neuroblastoma

This sample attributes table includes sample IDs, analyte type, tumor status, histological type, metastatic status, tumor stage and sequencing center.

pht004590
Descripción

pht004590

Alias
UMLS CUI [1,1]
C3846158
De-identified Sample ID
Descripción

SAMPLE_ID

Tipo de datos

string

Alias
UMLS CUI [1,1]
C4684638
UMLS CUI [1,2]
C1299222
Analyte Type
Descripción

ANALYTE_TYPE

Tipo de datos

string

Alias
UMLS CUI [1,1]
C4744818
Tumor status
Descripción

IS_TUMOR

Tipo de datos

text

Alias
UMLS CUI [1,1]
C0475752
Cell or tissue type or subtype of sample
Descripción

HISTOLOGICAL_TYPE

Tipo de datos

string

Alias
UMLS CUI [1,1]
C2347026
UMLS CUI [1,2]
C0007634
UMLS CUI [1,3]
C0332307
UMLS CUI [2,1]
C2347026
UMLS CUI [2,2]
C0007634
UMLS CUI [2,3]
C0449560
UMLS CUI [3,1]
C1292533
UMLS CUI [3,2]
C0332307
UMLS CUI [4,1]
C1292533
UMLS CUI [4,2]
C0449560
Primary tumor, metastasis, or transformed cell line
Descripción

PRIMARY_METASTATIC_TUMOR

Tipo de datos

string

Alias
UMLS CUI [1,1]
C0677930
UMLS CUI [2,1]
C0027627
UMLS CUI [3,1]
C0007601
Tumor stage of sample
Descripción

TUMOR_STAGE

Tipo de datos

string

Alias
UMLS CUI [1,1]
C1300072
UMLS CUI [1,2]
C0370003
Name of the center which conducted sequencing
Descripción

SEQUENCING_CENTER

Tipo de datos

string

Alias
UMLS CUI [1,1]
C1301943
UMLS CUI [1,2]
C0565990
UMLS CUI [1,3]
C1561491

Similar models

This sample attributes table includes sample IDs, analyte type, tumor status, histological type, metastatic status, tumor stage and sequencing center.

Name
Tipo
Description | Question | Decode (Coded Value)
Tipo de datos
Alias
Item Group
pht004590
C3846158 (UMLS CUI [1,1])
SAMPLE_ID
Item
De-identified Sample ID
string
C4684638 (UMLS CUI [1,1])
C1299222 (UMLS CUI [1,2])
ANALYTE_TYPE
Item
Analyte Type
string
C4744818 (UMLS CUI [1,1])
Item
Tumor status
text
C0475752 (UMLS CUI [1,1])
Code List
Tumor status
CL Item
Is not a tumor (N)
C0027651 (UMLS CUI [1,1])
C1518422 (UMLS CUI [1,2])
CL Item
Is Tumor (Y)
C0027651 (UMLS CUI [1,1])
HISTOLOGICAL_TYPE
Item
Cell or tissue type or subtype of sample
string
C2347026 (UMLS CUI [1,1])
C0007634 (UMLS CUI [1,2])
C0332307 (UMLS CUI [1,3])
C2347026 (UMLS CUI [2,1])
C0007634 (UMLS CUI [2,2])
C0449560 (UMLS CUI [2,3])
C1292533 (UMLS CUI [3,1])
C0332307 (UMLS CUI [3,2])
C1292533 (UMLS CUI [4,1])
C0449560 (UMLS CUI [4,2])
PRIMARY_METASTATIC_TUMOR
Item
Primary tumor, metastasis, or transformed cell line
string
C0677930 (UMLS CUI [1,1])
C0027627 (UMLS CUI [2,1])
C0007601 (UMLS CUI [3,1])
TUMOR_STAGE
Item
Tumor stage of sample
string
C1300072 (UMLS CUI [1,1])
C0370003 (UMLS CUI [1,2])
SEQUENCING_CENTER
Item
Name of the center which conducted sequencing
string
C1301943 (UMLS CUI [1,1])
C0565990 (UMLS CUI [1,2])
C1561491 (UMLS CUI [1,3])

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