ID
45960
Descrizione
Principal Investigator: Javed Khan, National Institutes of Health, Bethesda, MD, USA MeSH: Neuroblastoma https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000868 Neuroblastoma is the most common extra-cranial solid tumor in children. It represents 8% to 10% of all childhood cancers. Stage 4 Neuroblastoma is characterized by its clinical heterogeneous outcome. The special category, stage 4S tumors (2-5% of all NB) are chemo-sensitive, and the patients show spontaneous regression. On the other hand, MYCN amplification (25-30% of all NB) is associated with poor outcome of neuroblastoma, thus we further categorize stage 4 neuroblastoma into MYCN non-amplified and MYCN amplified group. Here we use transcriptome sequencing to characterize the transcriptome in 29 stage 4 Neuroblastoma samples.
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versioni (1)
- 16/03/24 16/03/24 - Madita Rudolph
Titolare del copyright
Javed Khan, National Institutes of Health, Bethesda, MD, USA
Caricato su
16 marzo 2024
DOI
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Licenza
Creative Commons BY 4.0
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dbGaP phs000868 Transcriptome Sequencing of Pediatric Neuroblastoma
The subject consent data table contains subject IDs and consent information.
- StudyEvent: SEV1
- Eligibility Criteria
- The subject consent data table contains subject IDs and consent information.
- The subject sample mapping data table contains mapping of study subject IDs to sample IDs. dbGaP samples are defined as the final preps submitted for genotyping, sequencing, and/or expression data. For example, if one patient (subject ID) gave one sample, and that sample was processed differently to generate 2 sequencing runs, there would be two rows, both using the same subject ID, but having 2 unique sample IDs. The data table also includes sample use.
- This subject phenotype table includes subject ID and age of onset.
- This sample attributes table includes sample IDs, analyte type, tumor status, histological type, metastatic status, tumor stage and sequencing center.
Similar models
The subject consent data table contains subject IDs and consent information.
- StudyEvent: SEV1
- Eligibility Criteria
- The subject consent data table contains subject IDs and consent information.
- The subject sample mapping data table contains mapping of study subject IDs to sample IDs. dbGaP samples are defined as the final preps submitted for genotyping, sequencing, and/or expression data. For example, if one patient (subject ID) gave one sample, and that sample was processed differently to generate 2 sequencing runs, there would be two rows, both using the same subject ID, but having 2 unique sample IDs. The data table also includes sample use.
- This subject phenotype table includes subject ID and age of onset.
- This sample attributes table includes sample IDs, analyte type, tumor status, histological type, metastatic status, tumor stage and sequencing center.
C0441833 (UMLS CUI [1,2])
C0242481 (UMLS CUI [1,2])
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