ID

45958

Beskrivning

Principal Investigator: Craig Wong MD MPH, University of New Mexico Health Sciences Center and UNM Children's Hospital, NM, USA MeSH: Kidney Diseases,Renal Insufficiency,Renal Insufficiency, Chronic https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000842 The Pediatric Investigation for Genetic Factors Associated with Renal Progression (PediGFR) (RO1-DK082394) is an international collaborative study among three large prospective cohort studies of children with chronic kidney disease. The participating parent cohort studies are the Chronic Kidney Disease in Children (CKiD), the Effect of Strict Blood Pressure Control and ACE Inhibition on CRF Progression in Pediatric Patients (ESCAPE), and the Cardiovascular Comorbidity in Children with Chronic Kidney Disease (4C) study. In these cohorts, pediatric subjects with CKD have been prospectively followed with standardized measurements for renal progression. The dbGaP data upload will utilize the structure of sub-studies to include the genotype and baseline phenotype for the three cohorts, as well as the RBC trait and anemia data for a sub-study under PI Susan Furth: Role of Genetic Variation in the Anemia of Chronic Kidney Disease (K24DK078737). In brief PediGFR is a prospective study of children with chronic kidney disease (CKD) to determine genetic factors associated with kidney function measured by the estimated glomerular filtration rate (eGFR) by Schwartz equation. *The PediGFR_v2 Cohort is utilized in the following dbGaP sub-studies.* To view genotypes, other molecular data, and derived variables collected in these sub-studies, please click on the following sub-studies below or in the "Sub-studies" box located on the right hand side of this top-level study page phs000842 PediGFR_v2 Cohort.- phs000843 4C - phs000650 CKiD - phs000844 ESCAPE

Länk

dbGaP study=phs000842

Nyckelord

  1. 3/16/24 3/16/24 - Madita Rudolph
Rättsinnehavare

Craig Wong MD MPH, University of New Mexico Health Sciences Center and UNM Children's Hospital, NM, USA

Uppladdad den

March 16, 2024

DOI

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Licens

Creative Commons BY 4.0

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dbGaP phs000842 PediGFR

Eligibility Criteria

  1. StudyEvent: SEV1
    1. Eligibility Criteria
    2. Subject ID, race, gender, whether genotyping is performed, child primary diagnosis, height, weight, tanner stage, and laboratory tests of participants with or without chronic kidney disease and involved in the "Pediatric Investigation for Genetic Factors Linked with Renal Progression (PediGFR), version with Chronic Kidney Disease in Children Cohort (CKiD)" project.
    3. Sample ID, analyte type, body site where sample was obtained, histological type of sample, and tumor status of sample of participants with or without chronic kidney disease and involved in the "Pediatric Investigation for Genetic Factors Linked with Renal Progression (PediGFR), version with Chronic Kidney Disease in Children Cohort (CKiD)" project.
    4. Subject ID, subject source, source subject ID, and consent group of participants with or without chronic kidney disease and involved in the "Pediatric Investigation for Genetic Factors Linked with Renal Progression (PediGFR)" project.
    5. Subject ID, sample ID, sample use, and study accession ID of participants with or without chronic kidney disease and involved in the "Pediatric Investigation for Genetic Factors Linked with Renal Progression (PediGFR)" project.
    6. Subject ID, race, country of residence, whether genotyping is performed, sex, child primary diagnosis, height, weight, tanner stage, and laboratory tests of participants with or without chronic kidney disease and involved in the "Pediatric Investigation for Genetic Factors Linked with Renal Disease Progression (PediGFR), version with Cardiovascular Comorbidity in Children with Chronic Kidney Disease (4C) Study" project.
    7. Sample ID, analyte type, body site where sample was obtained, histological type of sample, and tumor status of sample of participants with or without chronic kidney disease and involved in the "Pediatric Investigation for Genetic Factors Linked with Renal Disease Progression (PediGFR), version with Cardiovascular Comorbidity in Children with Chronic Kidney Disease (4C) Study" project.
    8. Subject ID, country of residence, whether genotyping is performed, gender, child primary diagnosis, height, weight, tanner stage, and laboratory tests of participants with or without chronic kidney disease and involved in the "Pediatric Investigation for Genetic Factors Linked with Renal Disease Progression (PediGFR), version with Effect of Strict Blood Pressure Control and ACE Inhibition on the Progression of CRF in Pediatric Patients (ESCAPE) Trial" project.
    9. Sample ID, analyte type, body site where sample was obtained, histological type of sample, and tumor status of samples obtained from participants with or without chronic kidney disease and involved in the "Pediatric Investigation for Genetic Factors Linked with Renal Disease Progression (PediGFR), version with Effect of Strict Blood Pressure Control and ACE Inhibition on the Progression of CRF in Pediatric Patients (ESCAPE) Trial" project.
Inclusion and exclusion criteria
Beskrivning

Inclusion and exclusion criteria

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0680251
The PediGFR utilized de-identified data from subjects who had consented for genetic testing, provided a sample of DNA, and who had data available for the renal trait phenotype as well and RBC trait and anemia phenotype. Exclusions are those who did not provide genetic consent, subject IDs whose genotyping did not pass quality control.
Beskrivning

Elig.phs000842.v2.p1.1

Datatyp

boolean

Alias
UMLS CUI [1,1]
C3242136
UMLS CUI [1,2]
C0021430
UMLS CUI [1,3]
C1320549
UMLS CUI [1,4]
C0370003
UMLS CUI [1,5]
C0012854
UMLS CUI [1,6]
C4035953
UMLS CUI [1,7]
C0031437
UMLS CUI [1,8]
C0232804
UMLS CUI [1,9]
C0014792
UMLS CUI [1,10]
C0002871
UMLS CUI [2,1]
C0680251
UMLS CUI [2,2]
C0021430
UMLS CUI [2,3]
C0332268
UMLS CUI [2,4]
C1285573
UMLS CUI [2,5]
C0034378

Similar models

Eligibility Criteria

  1. StudyEvent: SEV1
    1. Eligibility Criteria
    2. Subject ID, race, gender, whether genotyping is performed, child primary diagnosis, height, weight, tanner stage, and laboratory tests of participants with or without chronic kidney disease and involved in the "Pediatric Investigation for Genetic Factors Linked with Renal Progression (PediGFR), version with Chronic Kidney Disease in Children Cohort (CKiD)" project.
    3. Sample ID, analyte type, body site where sample was obtained, histological type of sample, and tumor status of sample of participants with or without chronic kidney disease and involved in the "Pediatric Investigation for Genetic Factors Linked with Renal Progression (PediGFR), version with Chronic Kidney Disease in Children Cohort (CKiD)" project.
    4. Subject ID, subject source, source subject ID, and consent group of participants with or without chronic kidney disease and involved in the "Pediatric Investigation for Genetic Factors Linked with Renal Progression (PediGFR)" project.
    5. Subject ID, sample ID, sample use, and study accession ID of participants with or without chronic kidney disease and involved in the "Pediatric Investigation for Genetic Factors Linked with Renal Progression (PediGFR)" project.
    6. Subject ID, race, country of residence, whether genotyping is performed, sex, child primary diagnosis, height, weight, tanner stage, and laboratory tests of participants with or without chronic kidney disease and involved in the "Pediatric Investigation for Genetic Factors Linked with Renal Disease Progression (PediGFR), version with Cardiovascular Comorbidity in Children with Chronic Kidney Disease (4C) Study" project.
    7. Sample ID, analyte type, body site where sample was obtained, histological type of sample, and tumor status of sample of participants with or without chronic kidney disease and involved in the "Pediatric Investigation for Genetic Factors Linked with Renal Disease Progression (PediGFR), version with Cardiovascular Comorbidity in Children with Chronic Kidney Disease (4C) Study" project.
    8. Subject ID, country of residence, whether genotyping is performed, gender, child primary diagnosis, height, weight, tanner stage, and laboratory tests of participants with or without chronic kidney disease and involved in the "Pediatric Investigation for Genetic Factors Linked with Renal Disease Progression (PediGFR), version with Effect of Strict Blood Pressure Control and ACE Inhibition on the Progression of CRF in Pediatric Patients (ESCAPE) Trial" project.
    9. Sample ID, analyte type, body site where sample was obtained, histological type of sample, and tumor status of samples obtained from participants with or without chronic kidney disease and involved in the "Pediatric Investigation for Genetic Factors Linked with Renal Disease Progression (PediGFR), version with Effect of Strict Blood Pressure Control and ACE Inhibition on the Progression of CRF in Pediatric Patients (ESCAPE) Trial" project.
Name
Typ
Description | Question | Decode (Coded Value)
Datatyp
Alias
Item Group
Inclusion and exclusion criteria
C1512693 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
Elig.phs000842.v2.p1.1
Item
The PediGFR utilized de-identified data from subjects who had consented for genetic testing, provided a sample of DNA, and who had data available for the renal trait phenotype as well and RBC trait and anemia phenotype. Exclusions are those who did not provide genetic consent, subject IDs whose genotyping did not pass quality control.
boolean
C3242136 (UMLS CUI [1,1])
C0021430 (UMLS CUI [1,2])
C1320549 (UMLS CUI [1,3])
C0370003 (UMLS CUI [1,4])
C0012854 (UMLS CUI [1,5])
C4035953 (UMLS CUI [1,6])
C0031437 (UMLS CUI [1,7])
C0232804 (UMLS CUI [1,8])
C0014792 (UMLS CUI [1,9])
C0002871 (UMLS CUI [1,10])
C0680251 (UMLS CUI [2,1])
C0021430 (UMLS CUI [2,2])
C0332268 (UMLS CUI [2,3])
C1285573 (UMLS CUI [2,4])
C0034378 (UMLS CUI [2,5])

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