ID
45910
Description
Principal Investigator: Rulla Tamimi, ScD, Brigham and Women's Hospital, Boston, MA, USA MeSH: Mammographic density,Breast Neoplasms https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000975 The Nurses' Health Study is an on-going prospective cohort study of women that was initiated in 1976. This specific study was part of a larger study to advance our knowledge of breast cancer etiology, expand the current knowledge of mammographic density, and clarify the relationship between mammographic density and breast cancer risk. We conducted a nested case control study of breast cancer among women who provided a blood sample. We then targeted our mammogram collection to participants that were selected as part of this nested case-control study (i.e. those who had provided a blood sample). The mammogram closest to the date of blood draw (~1989-1990) was used. We assessed mammographic breast density from digitized film images using a computer assisted thresholding method (Cumulus). The women in this study were genotyped using the Illumina Omni Express Platform.
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Versions (1)
- 1/22/24 1/22/24 - Simon Heim
Copyright Holder
Rulla Tamimi, ScD, Brigham and Women's Hospital, Boston, MA, USA
Uploaded on
January 22, 2024
DOI
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License
Creative Commons BY 4.0
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dbGaP phs000975 Nurses' Health Study (NHS)
The subject consent file includes subject IDs, consent information, and breast cancer status of the subject.
- StudyEvent: SEV1
- Eligibility Criteria
- The subject consent file includes subject IDs, consent information, and breast cancer status of the subject.
- This subject sample mapping data table contains a mapping of study subject IDs to sample IDs. Samples are the final preps submitted for genotyping, sequencing, and/or expression data. For example, if one patient (subject ID) gave one sample, and that sample was processed differently to generate 2 sequencing runs, there would be two rows, both using the same subject ID, but having 2 unique sample IDs. The data table also includes sample use.
- This subject phenotype table contains de-identified subject ID, breast cancer status, measurements at the time of mammogram (n=3 variables; age, menopausal status, and BMI), mean left and right mammographic measurements (n=4 variables; percent density and nondensity, breast area, and density area), principal components 1-4, tumor size and grade, and nodal status.
- This sample attributes table contains de-identified sample ID, body site where sample was collected, analyte type, and tumor status.
Similar models
The subject consent file includes subject IDs, consent information, and breast cancer status of the subject.
- StudyEvent: SEV1
- Eligibility Criteria
- The subject consent file includes subject IDs, consent information, and breast cancer status of the subject.
- This subject sample mapping data table contains a mapping of study subject IDs to sample IDs. Samples are the final preps submitted for genotyping, sequencing, and/or expression data. For example, if one patient (subject ID) gave one sample, and that sample was processed differently to generate 2 sequencing runs, there would be two rows, both using the same subject ID, but having 2 unique sample IDs. The data table also includes sample use.
- This subject phenotype table contains de-identified subject ID, breast cancer status, measurements at the time of mammogram (n=3 variables; age, menopausal status, and BMI), mean left and right mammographic measurements (n=4 variables; percent density and nondensity, breast area, and density area), principal components 1-4, tumor size and grade, and nodal status.
- This sample attributes table contains de-identified sample ID, body site where sample was collected, analyte type, and tumor status.
C0441833 (UMLS CUI [1,2])
C0242481 (UMLS CUI [1,2])
C0449437 (UMLS CUI [1,2])