ID

45876

Description

Principal Investigator: Mario Castro, MD, Washington University School of Medicine, St. Louis, MO, USA MeSH: Asthma,Bronchiolitis, Viral,Respiratory Syncytial Virus, Human https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001009 The goal of the RSV Bronchiolitis in Early Life (RBEL) study is to determine how specific genetic, biologic, and immunologic characteristics interact to predispose individuals to develop asthma. Participants were carefully recruited by selecting a prospective cohort of 206 infants with severe respiratory syncytial virus (RSV) bronchiolitis who were at substantial risk of developing asthma.

Link

dbGaP study = phs001009

Keywords

  1. 11/6/23 11/6/23 - Simon Heim
Copyright Holder

Mario Castro, MD, Washington University School of Medicine, St. Louis, MO, USA

Uploaded on

November 6, 2023

DOI

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License

Creative Commons BY 4.0

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dbGaP phs001009 Determinants of Asthma Following RSV Bronchiolitis in Early Life

Eligibility Criteria

Inclusion and exclusion criteria
Description

Inclusion and exclusion criteria

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0680251
Infants 12 months of age or younger were *included* in the RBEL study if they had severe bronchiolitis requiring emergency department care or hospitalization, a positive nasopharyngeal swab confirming RSV infection, and physician-documented wheezing during acute illness. *Exclusion* criteria included a history of previous wheezing and/or diagnosis of asthma, congenital abnormalities of the heart and lung, cystic fibrosis diagnosed in the patient or immediate family, regular use of anti-gastroesophageal reflux medication, bronchodilators, or anti-inflammatory medications.
Description

Infants 12 months of age or younger were *included* in the RBEL study if they had severe bronchiolitis requiring emergency department care or hospitalization, a positive nasopharyngeal swab confirming RSV infection, and physician-documented wheezing during acute illness. *Exclusion* criteria included a history of previous wheezing and/or diagnosis of asthma, congenital abnormalities of the heart and lung, cystic fibrosis diagnosed in the patient or immediate family, regular use of anti-gastroesophageal reflux medication, bronchodilators, or anti-inflammatory medications.

Data type

boolean

Alias
UMLS CUI [1,1]
C0021270
UMLS CUI [1,2]
C0001779
UMLS CUI [1,3]
C1512693
UMLS CUI [1,4]
C0947630
UMLS CUI [1,5]
C0006271
UMLS CUI [1,6]
C0205082
UMLS CUI [1,7]
C0583237
UMLS CUI [1,8]
C0019993
UMLS CUI [1,9]
C2266655
UMLS CUI [1,10]
C0035235
UMLS CUI [1,11]
C0031831
UMLS CUI [1,12]
C1301725
UMLS CUI [1,13]
C0043144
UMLS CUI [1,14]
C4061114
UMLS CUI [2,1]
C0680251
UMLS CUI [2,2]
C0262926
UMLS CUI [2,3]
C0043144
UMLS CUI [2,4]
C0011900
UMLS CUI [2,5]
C0004096
UMLS CUI [2,6]
C0018798
UMLS CUI [2,7]
C0158644
UMLS CUI [2,8]
C0010674
UMLS CUI [2,9]
C2371717
UMLS CUI [2,10]
C0240320
UMLS CUI [2,11]
C0205272
UMLS CUI [2,12]
C0017168
UMLS CUI [2,13]
C0006280
UMLS CUI [2,14]
C0003209

Similar models

Eligibility Criteria

Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
Inclusion and exclusion criteria
C1512693 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
Infants 12 months of age or younger were *included* in the RBEL study if they had severe bronchiolitis requiring emergency department care or hospitalization, a positive nasopharyngeal swab confirming RSV infection, and physician-documented wheezing during acute illness. *Exclusion* criteria included a history of previous wheezing and/or diagnosis of asthma, congenital abnormalities of the heart and lung, cystic fibrosis diagnosed in the patient or immediate family, regular use of anti-gastroesophageal reflux medication, bronchodilators, or anti-inflammatory medications.
Item
Infants 12 months of age or younger were *included* in the RBEL study if they had severe bronchiolitis requiring emergency department care or hospitalization, a positive nasopharyngeal swab confirming RSV infection, and physician-documented wheezing during acute illness. *Exclusion* criteria included a history of previous wheezing and/or diagnosis of asthma, congenital abnormalities of the heart and lung, cystic fibrosis diagnosed in the patient or immediate family, regular use of anti-gastroesophageal reflux medication, bronchodilators, or anti-inflammatory medications.
boolean
C0021270 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
C1512693 (UMLS CUI [1,3])
C0947630 (UMLS CUI [1,4])
C0006271 (UMLS CUI [1,5])
C0205082 (UMLS CUI [1,6])
C0583237 (UMLS CUI [1,7])
C0019993 (UMLS CUI [1,8])
C2266655 (UMLS CUI [1,9])
C0035235 (UMLS CUI [1,10])
C0031831 (UMLS CUI [1,11])
C1301725 (UMLS CUI [1,12])
C0043144 (UMLS CUI [1,13])
C4061114 (UMLS CUI [1,14])
C0680251 (UMLS CUI [2,1])
C0262926 (UMLS CUI [2,2])
C0043144 (UMLS CUI [2,3])
C0011900 (UMLS CUI [2,4])
C0004096 (UMLS CUI [2,5])
C0018798 (UMLS CUI [2,6])
C0158644 (UMLS CUI [2,7])
C0010674 (UMLS CUI [2,8])
C2371717 (UMLS CUI [2,9])
C0240320 (UMLS CUI [2,10])
C0205272 (UMLS CUI [2,11])
C0017168 (UMLS CUI [2,12])
C0006280 (UMLS CUI [2,13])
C0003209 (UMLS CUI [2,14])

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