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ID

45876

Descrizione

Principal Investigator: Mario Castro, MD, Washington University School of Medicine, St. Louis, MO, USA MeSH: Asthma,Bronchiolitis, Viral,Respiratory Syncytial Virus, Human https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001009 The goal of the RSV Bronchiolitis in Early Life (RBEL) study is to determine how specific genetic, biologic, and immunologic characteristics interact to predispose individuals to develop asthma. Participants were carefully recruited by selecting a prospective cohort of 206 infants with severe respiratory syncytial virus (RSV) bronchiolitis who were at substantial risk of developing asthma.

collegamento

dbGaP study = phs001009

Keywords

versioni (1)
  1. 06/11/23 06/11/23 - Simon Heim
Titolare del copyright

Mario Castro, MD, Washington University School of Medicine, St. Louis, MO, USA

Caricato su

6 novembre 2023

DOI

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Licenza

Creative Commons BY 4.0
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    dbGaP phs001009 Determinants of Asthma Following RSV Bronchiolitis in Early Life

    Inglese

    The dataset includes diagnosis information (asthma diagnosed by physician, reported wheezing episodes) and methacholine provocation concentration required to produce a 20% reduction of baseline forced expiratory volumne, plus basic sociodemographic data (gender, age in days).

    6 moduli  
    pht005352
    Descrizione

    pht005352

    Alias
    UMLS CUI [1,1]
    C3846158 (Other Coding)
    LOINC
    LA4728-7
    De-identified Subject ID
    Descrizione

    SUBJECT_ID

    Tipo di dati

    text

    Alias
    UMLS CUI [1,1]
    C4684638 (De-identified Information)
    UMLS CUI [1,2]
    C2348585 (Clinical Trial Subject Unique Identifier)
    Gender of participant
    Descrizione

    Gender

    Tipo di dati

    text

    Alias
    UMLS CUI [1,1]
    C0079399 (Gender)
    SNOMED
    263495000
    LOINC
    LP61312-2
    Self-reported race of participant
    Descrizione

    Race

    Tipo di dati

    text

    Alias
    UMLS CUI [1,1]
    C0034510 (Racial group)
    SNOMED
    415229000
    LOINC
    LP7528-5
    Age of participant when enrolled in the study
    Descrizione

    Age_at_enrollment_days

    Tipo di dati

    text

    Unità di misura
    • Days
    Alias
    UMLS CUI [1,1]
    C0001779 (Age)
    SNOMED
    424144002
    LOINC
    LP28815-6
    UMLS CUI [1,2]
    C1516879 (Enrollment)
    Days
    Physician-diagnosed asthma at any time before the child's 7th birthday
    Descrizione

    ASTHMA

    Tipo di dati

    text

    Alias
    UMLS CUI [1,1]
    C0031831 (Physicians)
    SNOMED
    158965000
    LOINC
    LA18968-0
    UMLS CUI [1,2]
    C0011900 (Diagnosis)
    SNOMED
    439401001
    LOINC
    LP30831-9
    UMLS CUI [1,3]
    C0004096 (Asthma)
    SNOMED
    195967001
    LOINC
    MTHU020815
    UMLS CUI [1,4]
    C0332152 (Before)
    SNOMED
    236874000
    UMLS CUI [1,5]
    C0001779 (Age)
    SNOMED
    424144002
    LOINC
    LP28815-6
    Physician-diagnosed asthma at any time with parent-reported wheezing during the last year of follow-up between the child's 3rd and 7th birthdays
    Descrizione

    Active_Asthma

    Tipo di dati

    text

    Alias
    UMLS CUI [1,1]
    C0031831 (Physicians)
    SNOMED
    158965000
    LOINC
    LA18968-0
    UMLS CUI [1,2]
    C0011900 (Diagnosis)
    SNOMED
    439401001
    LOINC
    LP30831-9
    UMLS CUI [1,3]
    C0004096 (Asthma)
    SNOMED
    195967001
    LOINC
    MTHU020815
    UMLS CUI [1,4]
    C0030551 (parent)
    SNOMED
    40683002
    LOINC
    LA30680-5
    UMLS CUI [1,5]
    C0700287 (Reporting)
    SNOMED
    223458004
    UMLS CUI [1,6]
    C0043144 (Wheezing)
    SNOMED
    56018004
    LOINC
    MTHU013532
    UMLS CUI [1,7]
    C0872291 (Time Interval)
    UMLS CUI [1,8]
    C1522577 (follow-up)
    UMLS CUI [1,9]
    C0001779 (Age)
    SNOMED
    424144002
    LOINC
    LP28815-6
    Having at least one wheezing episode in the first three years of life and at least one wheezing episode between the child's 3rd and 7th birthday
    Descrizione

    Persistent_wheezing

    Tipo di dati

    text

    Alias
    UMLS CUI [1,1]
    C0332189 (Episode of)
    SNOMED
    263503000
    UMLS CUI [1,2]
    C0043144 (Wheezing)
    SNOMED
    56018004
    LOINC
    MTHU013532
    UMLS CUI [1,3]
    C0872291 (Time Interval)
    Provocation concentration of inhaled methacholine that caused a 20% drop in baseline forced expiratory volume in one second at age 6
    Descrizione

    PC20_at_age_6_mg_dl

    Tipo di dati

    text

    Unità di misura
    • mg/dl
    Alias
    UMLS CUI [1,1]
    C2021458 (pulmonary function test FEV1 methacholine dose required to provoke 20% decrease)
    UMLS CUI [1,2]
    C0001779 (Age)
    SNOMED
    424144002
    LOINC
    LP28815-6
    Ritorna all'inizio della pagina

    Similar models

    The dataset includes diagnosis information (asthma diagnosed by physician, reported wheezing episodes) and methacholine provocation concentration required to produce a 20% reduction of baseline forced expiratory volumne, plus basic sociodemographic data (gender, age in days).

    6 moduli
    Name
    genere
    Description | Question | Decode (Coded Value)
    Tipo di dati
    Alias
    Item Group
    pht005352
    C3846158 (UMLS CUI [1,1])
    SUBJECT_ID
    Item
    De-identified Subject ID
    text
    C4684638 (UMLS CUI [1,1])
    C2348585 (UMLS CUI [1,2])
    Item
    Gender of participant
    text
    C0079399 (UMLS CUI [1,1])
    Gender
    Code List
    Gender of participant
    CL Item
    Male (0)
    C0086582 (UMLS CUI [1,1])
    CL Item
    Female (1)
    C0086287 (UMLS CUI [1,1])
    Item
    Self-reported race of participant
    text
    C0034510 (UMLS CUI [1,1])
    Race
    Code List
    Self-reported race of participant
    CL Item
    African American (0)
    CL Item
    Caucasian (1)
    Age_at_enrollment_days
    Item
    Age of participant when enrolled in the study
    text
    C0001779 (UMLS CUI [1,1])
    C1516879 (UMLS CUI [1,2])
    Item
    Physician-diagnosed asthma at any time before the child's 7th birthday
    text
    C0031831 (UMLS CUI [1,1])
    C0011900 (UMLS CUI [1,2])
    C0004096 (UMLS CUI [1,3])
    C0332152 (UMLS CUI [1,4])
    C0001779 (UMLS CUI [1,5])
    ASTHMA
    Code List
    Physician-diagnosed asthma at any time before the child's 7th birthday
    CL Item
    No (0)
    CL Item
    Yes (1)
    Item
    Physician-diagnosed asthma at any time with parent-reported wheezing during the last year of follow-up between the child's 3rd and 7th birthdays
    text
    C0031831 (UMLS CUI [1,1])
    C0011900 (UMLS CUI [1,2])
    C0004096 (UMLS CUI [1,3])
    C0030551 (UMLS CUI [1,4])
    C0700287 (UMLS CUI [1,5])
    C0043144 (UMLS CUI [1,6])
    C0872291 (UMLS CUI [1,7])
    C1522577 (UMLS CUI [1,8])
    C0001779 (UMLS CUI [1,9])
    Active_Asthma
    Code List
    Physician-diagnosed asthma at any time with parent-reported wheezing during the last year of follow-up between the child's 3rd and 7th birthdays
    CL Item
    No (0)
    CL Item
    Yes (1)
    CL Item
    Unknown (-9)
    Item
    Having at least one wheezing episode in the first three years of life and at least one wheezing episode between the child's 3rd and 7th birthday
    text
    C0332189 (UMLS CUI [1,1])
    C0043144 (UMLS CUI [1,2])
    C0872291 (UMLS CUI [1,3])
    Persistent_wheezing
    Code List
    Having at least one wheezing episode in the first three years of life and at least one wheezing episode between the child's 3rd and 7th birthday
    CL Item
    No (0)
    CL Item
    Yes (1)
    CL Item
    Unknown (-9)
    Item
    Provocation concentration of inhaled methacholine that caused a 20% drop in baseline forced expiratory volume in one second at age 6
    text
    C2021458 (UMLS CUI [1,1])
    C0001779 (UMLS CUI [1,2])
    PC20_at_age_6_mg_dl
    Code List
    Provocation concentration of inhaled methacholine that caused a 20% drop in baseline forced expiratory volume in one second at age 6
    CL Item
    Unknown (-9)
    Ritorna all'inizio della pagina 

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