ID

45876

Description

Principal Investigator: Mario Castro, MD, Washington University School of Medicine, St. Louis, MO, USA MeSH: Asthma,Bronchiolitis, Viral,Respiratory Syncytial Virus, Human https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001009 The goal of the RSV Bronchiolitis in Early Life (RBEL) study is to determine how specific genetic, biologic, and immunologic characteristics interact to predispose individuals to develop asthma. Participants were carefully recruited by selecting a prospective cohort of 206 infants with severe respiratory syncytial virus (RSV) bronchiolitis who were at substantial risk of developing asthma.

Link

dbGaP study = phs001009

Keywords

Versions (1)
  1. 11/6/23 11/6/23 - Simon Heim
Copyright Holder

Mario Castro, MD, Washington University School of Medicine, St. Louis, MO, USA

Uploaded on

November 6, 2023

DOI

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License

Creative Commons BY 4.0
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dbGaP phs001009 Determinants of Asthma Following RSV Bronchiolitis in Early Life

English

The dataset includes diagnosis information (asthma diagnosed by physician, reported wheezing episodes) and methacholine provocation concentration required to produce a 20% reduction of baseline forced expiratory volumne, plus basic sociodemographic data (gender, age in days).

6 forms  
pht005352
Description

pht005352

Alias
UMLS CUI [1,1]
C3846158
De-identified Subject ID
Description

SUBJECT_ID

Data type

text

Alias
UMLS CUI [1,1]
C4684638
UMLS CUI [1,2]
C2348585
Gender of participant
Description

Gender

Data type

text

Alias
UMLS CUI [1,1]
C0079399
Self-reported race of participant
Description

Race

Data type

text

Alias
UMLS CUI [1,1]
C0034510
Age of participant when enrolled in the study
Description

Age_at_enrollment_days

Data type

text

Measurement units
  • Days
Alias
UMLS CUI [1,1]
C0001779
UMLS CUI [1,2]
C1516879
Days
Physician-diagnosed asthma at any time before the child's 7th birthday
Description

ASTHMA

Data type

text

Alias
UMLS CUI [1,1]
C0031831
UMLS CUI [1,2]
C0011900
UMLS CUI [1,3]
C0004096
UMLS CUI [1,4]
C0332152
UMLS CUI [1,5]
C0001779
Physician-diagnosed asthma at any time with parent-reported wheezing during the last year of follow-up between the child's 3rd and 7th birthdays
Description

Active_Asthma

Data type

text

Alias
UMLS CUI [1,1]
C0031831
UMLS CUI [1,2]
C0011900
UMLS CUI [1,3]
C0004096
UMLS CUI [1,4]
C0030551
UMLS CUI [1,5]
C0700287
UMLS CUI [1,6]
C0043144
UMLS CUI [1,7]
C0872291
UMLS CUI [1,8]
C1522577
UMLS CUI [1,9]
C0001779
Having at least one wheezing episode in the first three years of life and at least one wheezing episode between the child's 3rd and 7th birthday
Description

Persistent_wheezing

Data type

text

Alias
UMLS CUI [1,1]
C0332189
UMLS CUI [1,2]
C0043144
UMLS CUI [1,3]
C0872291
Provocation concentration of inhaled methacholine that caused a 20% drop in baseline forced expiratory volume in one second at age 6
Description

PC20_at_age_6_mg_dl

Data type

text

Measurement units
  • mg/dl
Alias
UMLS CUI [1,1]
C2021458
UMLS CUI [1,2]
C0001779
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Similar models

The dataset includes diagnosis information (asthma diagnosed by physician, reported wheezing episodes) and methacholine provocation concentration required to produce a 20% reduction of baseline forced expiratory volumne, plus basic sociodemographic data (gender, age in days).

6 forms
Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
pht005352
C3846158 (UMLS CUI [1,1])
SUBJECT_ID
Item
De-identified Subject ID
text
C4684638 (UMLS CUI [1,1])
C2348585 (UMLS CUI [1,2])
Item
Gender of participant
text
C0079399 (UMLS CUI [1,1])
Gender
Code List
Gender of participant
CL Item
Male (0)
C0086582 (UMLS CUI [1,1])
CL Item
Female (1)
C0086287 (UMLS CUI [1,1])
Item
Self-reported race of participant
text
C0034510 (UMLS CUI [1,1])
Race
Code List
Self-reported race of participant
CL Item
African American (0)
CL Item
Caucasian (1)
Age_at_enrollment_days
Item
Age of participant when enrolled in the study
text
C0001779 (UMLS CUI [1,1])
C1516879 (UMLS CUI [1,2])
Item
Physician-diagnosed asthma at any time before the child's 7th birthday
text
C0031831 (UMLS CUI [1,1])
C0011900 (UMLS CUI [1,2])
C0004096 (UMLS CUI [1,3])
C0332152 (UMLS CUI [1,4])
C0001779 (UMLS CUI [1,5])
ASTHMA
Code List
Physician-diagnosed asthma at any time before the child's 7th birthday
CL Item
No (0)
CL Item
Yes (1)
Item
Physician-diagnosed asthma at any time with parent-reported wheezing during the last year of follow-up between the child's 3rd and 7th birthdays
text
C0031831 (UMLS CUI [1,1])
C0011900 (UMLS CUI [1,2])
C0004096 (UMLS CUI [1,3])
C0030551 (UMLS CUI [1,4])
C0700287 (UMLS CUI [1,5])
C0043144 (UMLS CUI [1,6])
C0872291 (UMLS CUI [1,7])
C1522577 (UMLS CUI [1,8])
C0001779 (UMLS CUI [1,9])
Active_Asthma
Code List
Physician-diagnosed asthma at any time with parent-reported wheezing during the last year of follow-up between the child's 3rd and 7th birthdays
CL Item
No (0)
CL Item
Yes (1)
CL Item
Unknown (-9)
Item
Having at least one wheezing episode in the first three years of life and at least one wheezing episode between the child's 3rd and 7th birthday
text
C0332189 (UMLS CUI [1,1])
C0043144 (UMLS CUI [1,2])
C0872291 (UMLS CUI [1,3])
Persistent_wheezing
Code List
Having at least one wheezing episode in the first three years of life and at least one wheezing episode between the child's 3rd and 7th birthday
CL Item
No (0)
CL Item
Yes (1)
CL Item
Unknown (-9)
Item
Provocation concentration of inhaled methacholine that caused a 20% drop in baseline forced expiratory volume in one second at age 6
text
C2021458 (UMLS CUI [1,1])
C0001779 (UMLS CUI [1,2])
PC20_at_age_6_mg_dl
Code List
Provocation concentration of inhaled methacholine that caused a 20% drop in baseline forced expiratory volume in one second at age 6
CL Item
Unknown (-9)
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