ID

45876

Descripción

Principal Investigator: Mario Castro, MD, Washington University School of Medicine, St. Louis, MO, USA MeSH: Asthma,Bronchiolitis, Viral,Respiratory Syncytial Virus, Human https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001009 The goal of the RSV Bronchiolitis in Early Life (RBEL) study is to determine how specific genetic, biologic, and immunologic characteristics interact to predispose individuals to develop asthma. Participants were carefully recruited by selecting a prospective cohort of 206 infants with severe respiratory syncytial virus (RSV) bronchiolitis who were at substantial risk of developing asthma.

Link

dbGaP study = phs001009

Palabras clave

Versiones (1)
  1. 6/11/23 6/11/23 - Simon Heim
Titular de derechos de autor

Mario Castro, MD, Washington University School of Medicine, St. Louis, MO, USA

Subido en

6 de noviembre de 2023

DOI

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Licencia

Creative Commons BY 4.0
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    dbGaP phs001009 Determinants of Asthma Following RSV Bronchiolitis in Early Life

    Inglés

    The dataset includes diagnosis information (asthma diagnosed by physician, reported wheezing episodes) and methacholine provocation concentration required to produce a 20% reduction of baseline forced expiratory volumne, plus basic sociodemographic data (gender, age in days).

    6 formularios  
    pht005352
    Descripción

    pht005352

    Alias
    UMLS CUI [1,1]
    C3846158
    De-identified Subject ID
    Descripción

    SUBJECT_ID

    Tipo de datos

    text

    Alias
    UMLS CUI [1,1]
    C4684638
    UMLS CUI [1,2]
    C2348585
    Gender of participant
    Descripción

    Gender

    Tipo de datos

    text

    Alias
    UMLS CUI [1,1]
    C0079399
    Self-reported race of participant
    Descripción

    Race

    Tipo de datos

    text

    Alias
    UMLS CUI [1,1]
    C0034510
    Age of participant when enrolled in the study
    Descripción

    Age_at_enrollment_days

    Tipo de datos

    text

    Unidades de medida
    • Days
    Alias
    UMLS CUI [1,1]
    C0001779
    UMLS CUI [1,2]
    C1516879
    Days
    Physician-diagnosed asthma at any time before the child's 7th birthday
    Descripción

    ASTHMA

    Tipo de datos

    text

    Alias
    UMLS CUI [1,1]
    C0031831
    UMLS CUI [1,2]
    C0011900
    UMLS CUI [1,3]
    C0004096
    UMLS CUI [1,4]
    C0332152
    UMLS CUI [1,5]
    C0001779
    Physician-diagnosed asthma at any time with parent-reported wheezing during the last year of follow-up between the child's 3rd and 7th birthdays
    Descripción

    Active_Asthma

    Tipo de datos

    text

    Alias
    UMLS CUI [1,1]
    C0031831
    UMLS CUI [1,2]
    C0011900
    UMLS CUI [1,3]
    C0004096
    UMLS CUI [1,4]
    C0030551
    UMLS CUI [1,5]
    C0700287
    UMLS CUI [1,6]
    C0043144
    UMLS CUI [1,7]
    C0872291
    UMLS CUI [1,8]
    C1522577
    UMLS CUI [1,9]
    C0001779
    Having at least one wheezing episode in the first three years of life and at least one wheezing episode between the child's 3rd and 7th birthday
    Descripción

    Persistent_wheezing

    Tipo de datos

    text

    Alias
    UMLS CUI [1,1]
    C0332189
    UMLS CUI [1,2]
    C0043144
    UMLS CUI [1,3]
    C0872291
    Provocation concentration of inhaled methacholine that caused a 20% drop in baseline forced expiratory volume in one second at age 6
    Descripción

    PC20_at_age_6_mg_dl

    Tipo de datos

    text

    Unidades de medida
    • mg/dl
    Alias
    UMLS CUI [1,1]
    C2021458
    UMLS CUI [1,2]
    C0001779
    Volver a la parte superior de la página

    Similar models

    The dataset includes diagnosis information (asthma diagnosed by physician, reported wheezing episodes) and methacholine provocation concentration required to produce a 20% reduction of baseline forced expiratory volumne, plus basic sociodemographic data (gender, age in days).

    6 formularios
    Name
    Tipo
    Description | Question | Decode (Coded Value)
    Tipo de datos
    Alias
    Item Group
    pht005352
    C3846158 (UMLS CUI [1,1])
    SUBJECT_ID
    Item
    De-identified Subject ID
    text
    C4684638 (UMLS CUI [1,1])
    C2348585 (UMLS CUI [1,2])
    Item
    Gender of participant
    text
    C0079399 (UMLS CUI [1,1])
    Gender
    Code List
    Gender of participant
    CL Item
    Male (0)
    C0086582 (UMLS CUI [1,1])
    CL Item
    Female (1)
    C0086287 (UMLS CUI [1,1])
    Item
    Self-reported race of participant
    text
    C0034510 (UMLS CUI [1,1])
    Race
    Code List
    Self-reported race of participant
    CL Item
    African American (0)
    CL Item
    Caucasian (1)
    Age_at_enrollment_days
    Item
    Age of participant when enrolled in the study
    text
    C0001779 (UMLS CUI [1,1])
    C1516879 (UMLS CUI [1,2])
    Item
    Physician-diagnosed asthma at any time before the child's 7th birthday
    text
    C0031831 (UMLS CUI [1,1])
    C0011900 (UMLS CUI [1,2])
    C0004096 (UMLS CUI [1,3])
    C0332152 (UMLS CUI [1,4])
    C0001779 (UMLS CUI [1,5])
    ASTHMA
    Code List
    Physician-diagnosed asthma at any time before the child's 7th birthday
    CL Item
    No (0)
    CL Item
    Yes (1)
    Item
    Physician-diagnosed asthma at any time with parent-reported wheezing during the last year of follow-up between the child's 3rd and 7th birthdays
    text
    C0031831 (UMLS CUI [1,1])
    C0011900 (UMLS CUI [1,2])
    C0004096 (UMLS CUI [1,3])
    C0030551 (UMLS CUI [1,4])
    C0700287 (UMLS CUI [1,5])
    C0043144 (UMLS CUI [1,6])
    C0872291 (UMLS CUI [1,7])
    C1522577 (UMLS CUI [1,8])
    C0001779 (UMLS CUI [1,9])
    Active_Asthma
    Code List
    Physician-diagnosed asthma at any time with parent-reported wheezing during the last year of follow-up between the child's 3rd and 7th birthdays
    CL Item
    No (0)
    CL Item
    Yes (1)
    CL Item
    Unknown (-9)
    Item
    Having at least one wheezing episode in the first three years of life and at least one wheezing episode between the child's 3rd and 7th birthday
    text
    C0332189 (UMLS CUI [1,1])
    C0043144 (UMLS CUI [1,2])
    C0872291 (UMLS CUI [1,3])
    Persistent_wheezing
    Code List
    Having at least one wheezing episode in the first three years of life and at least one wheezing episode between the child's 3rd and 7th birthday
    CL Item
    No (0)
    CL Item
    Yes (1)
    CL Item
    Unknown (-9)
    Item
    Provocation concentration of inhaled methacholine that caused a 20% drop in baseline forced expiratory volume in one second at age 6
    text
    C2021458 (UMLS CUI [1,1])
    C0001779 (UMLS CUI [1,2])
    PC20_at_age_6_mg_dl
    Code List
    Provocation concentration of inhaled methacholine that caused a 20% drop in baseline forced expiratory volume in one second at age 6
    CL Item
    Unknown (-9)
    Volver a la parte superior de la página 

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