ID

45876

Description

Principal Investigator: Mario Castro, MD, Washington University School of Medicine, St. Louis, MO, USA MeSH: Asthma,Bronchiolitis, Viral,Respiratory Syncytial Virus, Human https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001009 The goal of the RSV Bronchiolitis in Early Life (RBEL) study is to determine how specific genetic, biologic, and immunologic characteristics interact to predispose individuals to develop asthma. Participants were carefully recruited by selecting a prospective cohort of 206 infants with severe respiratory syncytial virus (RSV) bronchiolitis who were at substantial risk of developing asthma.

Lien

dbGaP study = phs001009

Mots-clés

  1. 06/11/2023 06/11/2023 - Simon Heim
Détendeur de droits

Mario Castro, MD, Washington University School of Medicine, St. Louis, MO, USA

Téléchargé le

6 novembre 2023

DOI

Pour une demande vous connecter.

Licence

Creative Commons BY 4.0

Modèle Commentaires :

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    dbGaP phs001009 Determinants of Asthma Following RSV Bronchiolitis in Early Life

    The dataset includes diagnosis information (asthma diagnosed by physician, reported wheezing episodes) and methacholine provocation concentration required to produce a 20% reduction of baseline forced expiratory volumne, plus basic sociodemographic data (gender, age in days).

    pht005352
    Description

    pht005352

    Alias
    UMLS CUI [1,1]
    C3846158
    De-identified Subject ID
    Description

    SUBJECT_ID

    Type de données

    text

    Alias
    UMLS CUI [1,1]
    C4684638
    UMLS CUI [1,2]
    C2348585
    Gender of participant
    Description

    Gender

    Type de données

    text

    Alias
    UMLS CUI [1,1]
    C0079399
    Self-reported race of participant
    Description

    Race

    Type de données

    text

    Alias
    UMLS CUI [1,1]
    C0034510
    Age of participant when enrolled in the study
    Description

    Age_at_enrollment_days

    Type de données

    text

    Unités de mesure
    • Days
    Alias
    UMLS CUI [1,1]
    C0001779
    UMLS CUI [1,2]
    C1516879
    Days
    Physician-diagnosed asthma at any time before the child's 7th birthday
    Description

    ASTHMA

    Type de données

    text

    Alias
    UMLS CUI [1,1]
    C0031831
    UMLS CUI [1,2]
    C0011900
    UMLS CUI [1,3]
    C0004096
    UMLS CUI [1,4]
    C0332152
    UMLS CUI [1,5]
    C0001779
    Physician-diagnosed asthma at any time with parent-reported wheezing during the last year of follow-up between the child's 3rd and 7th birthdays
    Description

    Active_Asthma

    Type de données

    text

    Alias
    UMLS CUI [1,1]
    C0031831
    UMLS CUI [1,2]
    C0011900
    UMLS CUI [1,3]
    C0004096
    UMLS CUI [1,4]
    C0030551
    UMLS CUI [1,5]
    C0700287
    UMLS CUI [1,6]
    C0043144
    UMLS CUI [1,7]
    C0872291
    UMLS CUI [1,8]
    C1522577
    UMLS CUI [1,9]
    C0001779
    Having at least one wheezing episode in the first three years of life and at least one wheezing episode between the child's 3rd and 7th birthday
    Description

    Persistent_wheezing

    Type de données

    text

    Alias
    UMLS CUI [1,1]
    C0332189
    UMLS CUI [1,2]
    C0043144
    UMLS CUI [1,3]
    C0872291
    Provocation concentration of inhaled methacholine that caused a 20% drop in baseline forced expiratory volume in one second at age 6
    Description

    PC20_at_age_6_mg_dl

    Type de données

    text

    Unités de mesure
    • mg/dl
    Alias
    UMLS CUI [1,1]
    C2021458
    UMLS CUI [1,2]
    C0001779

    Similar models

    The dataset includes diagnosis information (asthma diagnosed by physician, reported wheezing episodes) and methacholine provocation concentration required to produce a 20% reduction of baseline forced expiratory volumne, plus basic sociodemographic data (gender, age in days).

    Name
    Type
    Description | Question | Decode (Coded Value)
    Type de données
    Alias
    Item Group
    pht005352
    C3846158 (UMLS CUI [1,1])
    SUBJECT_ID
    Item
    De-identified Subject ID
    text
    C4684638 (UMLS CUI [1,1])
    C2348585 (UMLS CUI [1,2])
    Item
    Gender of participant
    text
    C0079399 (UMLS CUI [1,1])
    Code List
    Gender of participant
    CL Item
    Male (0)
    C0086582 (UMLS CUI [1,1])
    CL Item
    Female (1)
    C0086287 (UMLS CUI [1,1])
    Item
    Self-reported race of participant
    text
    C0034510 (UMLS CUI [1,1])
    Code List
    Self-reported race of participant
    CL Item
    African American (0)
    CL Item
    Caucasian (1)
    Age_at_enrollment_days
    Item
    Age of participant when enrolled in the study
    text
    C0001779 (UMLS CUI [1,1])
    C1516879 (UMLS CUI [1,2])
    Item
    Physician-diagnosed asthma at any time before the child's 7th birthday
    text
    C0031831 (UMLS CUI [1,1])
    C0011900 (UMLS CUI [1,2])
    C0004096 (UMLS CUI [1,3])
    C0332152 (UMLS CUI [1,4])
    C0001779 (UMLS CUI [1,5])
    Code List
    Physician-diagnosed asthma at any time before the child's 7th birthday
    CL Item
    No (0)
    CL Item
    Yes (1)
    Item
    Physician-diagnosed asthma at any time with parent-reported wheezing during the last year of follow-up between the child's 3rd and 7th birthdays
    text
    C0031831 (UMLS CUI [1,1])
    C0011900 (UMLS CUI [1,2])
    C0004096 (UMLS CUI [1,3])
    C0030551 (UMLS CUI [1,4])
    C0700287 (UMLS CUI [1,5])
    C0043144 (UMLS CUI [1,6])
    C0872291 (UMLS CUI [1,7])
    C1522577 (UMLS CUI [1,8])
    C0001779 (UMLS CUI [1,9])
    Code List
    Physician-diagnosed asthma at any time with parent-reported wheezing during the last year of follow-up between the child's 3rd and 7th birthdays
    CL Item
    No (0)
    CL Item
    Yes (1)
    CL Item
    Unknown (-9)
    Item
    Having at least one wheezing episode in the first three years of life and at least one wheezing episode between the child's 3rd and 7th birthday
    text
    C0332189 (UMLS CUI [1,1])
    C0043144 (UMLS CUI [1,2])
    C0872291 (UMLS CUI [1,3])
    Code List
    Having at least one wheezing episode in the first three years of life and at least one wheezing episode between the child's 3rd and 7th birthday
    CL Item
    No (0)
    CL Item
    Yes (1)
    CL Item
    Unknown (-9)
    Item
    Provocation concentration of inhaled methacholine that caused a 20% drop in baseline forced expiratory volume in one second at age 6
    text
    C2021458 (UMLS CUI [1,1])
    C0001779 (UMLS CUI [1,2])
    Code List
    Provocation concentration of inhaled methacholine that caused a 20% drop in baseline forced expiratory volume in one second at age 6
    CL Item
    Unknown (-9)

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