ID
45838
Beschrijving
Principal Investigator: MeSH: Lupus Erythematosus, Systemic https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001025 The study comprises SLE patients recruited from specialist rheumatology clinics from the United States, Mexico, Argentina, Chile and Peru. Two strategies were used to enrich samples for Native American ancestry: a. previously genotyped Hispanic and Latin American and US Native American individuals were selected according to their ancestry based on 253 ancestry informative markers as part of the Lupus Large Association 2 Study. The approximate 35% of the samples were primarily of European and Native American admixture was selected; b. the recruitment of patients took place primarily in countries with little African admixture. All samples were genotyped on the HumanOmni1-Quad BeadChip using manifest H at the Oklahoma Medical Research Foundation. The Illumina clustering algorithm with GenomeStudio v2011.1 was used.
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- 15-08-23 15-08-23 - Simon Heim
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dbGAP
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15 augustus 2023
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Creative Commons BY 4.0
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dbGaP phs001025 Hispanic Lupus GWAS_HISPSLEI Study
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID, consent group, and affection status of participants with or without systemic lupus erythematosus and involved in the "GWAS in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture" project.
- Subject ID, sample ID, and sample use variable obtained from participants with or without systemic lupus erythematosus and involved in the "GWAS in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture" project.
- Subject ID, gender, and status of systemic lupus erythematosus of participants with or without systemic lupus erythematosus and involved in the "GWAS in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture" project.
- Sample ID, body site where sample was obtained, analyte type, tumor status of sample, subject country of origin, and principal component 1,2,3,4, and 5 of participants with or without systemic lupus erythematosus and involved in the "GWAS in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture" project.
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Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID, consent group, and affection status of participants with or without systemic lupus erythematosus and involved in the "GWAS in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture" project.
- Subject ID, sample ID, and sample use variable obtained from participants with or without systemic lupus erythematosus and involved in the "GWAS in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture" project.
- Subject ID, gender, and status of systemic lupus erythematosus of participants with or without systemic lupus erythematosus and involved in the "GWAS in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture" project.
- Sample ID, body site where sample was obtained, analyte type, tumor status of sample, subject country of origin, and principal component 1,2,3,4, and 5 of participants with or without systemic lupus erythematosus and involved in the "GWAS in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture" project.
C0680251 (UMLS CUI [1,2])
C0021430 (UMLS CUI [1,2])
C0079399 (UMLS CUI [1,3])
C4055473 (UMLS CUI [1,4])
C0009932 (UMLS CUI [2,1])
C0150103 (UMLS CUI [2,2])
C0079399 (UMLS CUI [2,3])
C0001779 (UMLS CUI [2,4])
C2949735 (UMLS CUI [2,5])
C2825164 (UMLS CUI [2,6])