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45823
Beschrijving
Principal Investigator: Stephen B. Gruber, USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA MeSH: Colorectal Neoplasms https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001045 This study compared Ashkenazi Jewish individuals with Stage IV metastatic colon cancer to those with non-metastatic Stage I or II colon cancers. A genome-wide association study, using a 2-stage design, identified a significant association with rs60745952.
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- 09-07-23 09-07-23 - Simon Heim
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Stephen B. Gruber, USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA
Geüploaded op
9 juli 2023
DOI
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Creative Commons BY 4.0
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dbGaP phs001045 Molecular Epidemiology of Colorectal Cancer (MECC) Metastasis Study
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID and consent group of participants with or without colorectal cancer and involved in the "Molecular Epidemiology of Colorectal Cancer (MECC) Metastasis Study: A Germline Variant on Chromosome 4q31.1 Associates with Susceptibility to Developing Colon Cancer Metastasis" project.
- Subject ID and sample ID of participants with or without colorectal cancer and involved in the "Molecular Epidemiology of Colorectal Cancer (MECC) Metastasis Study: A Germline Variant on Chromosome 4q31.1 Associates with Susceptibility to Developing Colon Cancer Metastasis" project.
- Subject ID, sex, affection status, age at diagnosis, and colorectal cancer stage category of participants with or without colorectal cancer and involved in the "Molecular Epidemiology of Colorectal Cancer (MECC) Metastasis Study: A Germline Variant on Chromosome 4q31.1 Associates with Susceptibility to Developing Colon Cancer Metastasis" project.
- Sample ID, analyte type, body site where from sample was obtained, histological type of sample, and tumor status of sample obtained from participants with or without colorectal cancer and involved in the "Molecular Epidemiology of Colorectal Cancer (MECC) Metastasis Study: A Germline Variant on Chromosome 4q31.1 Associates with Susceptibility to Developing Colon Cancer Metastasis" project.
Similar models
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID and consent group of participants with or without colorectal cancer and involved in the "Molecular Epidemiology of Colorectal Cancer (MECC) Metastasis Study: A Germline Variant on Chromosome 4q31.1 Associates with Susceptibility to Developing Colon Cancer Metastasis" project.
- Subject ID and sample ID of participants with or without colorectal cancer and involved in the "Molecular Epidemiology of Colorectal Cancer (MECC) Metastasis Study: A Germline Variant on Chromosome 4q31.1 Associates with Susceptibility to Developing Colon Cancer Metastasis" project.
- Subject ID, sex, affection status, age at diagnosis, and colorectal cancer stage category of participants with or without colorectal cancer and involved in the "Molecular Epidemiology of Colorectal Cancer (MECC) Metastasis Study: A Germline Variant on Chromosome 4q31.1 Associates with Susceptibility to Developing Colon Cancer Metastasis" project.
- Sample ID, analyte type, body site where from sample was obtained, histological type of sample, and tumor status of sample obtained from participants with or without colorectal cancer and involved in the "Molecular Epidemiology of Colorectal Cancer (MECC) Metastasis Study: A Germline Variant on Chromosome 4q31.1 Associates with Susceptibility to Developing Colon Cancer Metastasis" project.
Name
Type
Description | Question | Decode (Coded Value)
Datatype
Alias
Item Group
Inclusion and exclusion criteria
C1512693 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
C0680251 (UMLS CUI [1,2])
*Inclusion Criteria* Cases Diagnosis with a primary colorectal cancer Stage IV, Stage I, Stage II Ashkenazi Jewish/Jewish
Item
*Inclusion Criteria* Cases Diagnosis with a primary colorectal cancer Stage IV, Stage I, Stage II Ashkenazi Jewish/Jewish
boolean
C1512693 (UMLS CUI [1,1])
C0011900 (UMLS CUI [1,2])
C0677950 (UMLS CUI [1,3])
C0677947 (UMLS CUI [1,4])
C0677948 (UMLS CUI [1,5])
C3844810 (UMLS CUI [1,6])
C0011900 (UMLS CUI [1,2])
C0677950 (UMLS CUI [1,3])
C0677947 (UMLS CUI [1,4])
C0677948 (UMLS CUI [1,5])
C3844810 (UMLS CUI [1,6])
*Exclusion Criteria* Stage III colon cancer Rectal cancer
Item
*Exclusion Criteria* Stage III colon cancer Rectal cancer
boolean
C0680251 (UMLS CUI [1,1])
C0278480 (UMLS CUI [1,2])
C0278480 (UMLS CUI [1,2])