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ID
45822
Beschrijving
Principal Investigator: MeSH: Neoplasms,Sarcoma,Sarcoma, Ewing,Rhabdomyosarcoma,Wilms Tumor,Desmoplastic Small Round Cell Tumor,Carcinoma, Transitional Cell,Rhabdoid Tumor,Sarcoma, Synovial,Neuroblastoma,Neuroendocrine tumors https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001052 The Center for Cancer Research (CCR), of the intramural NCI undertook a multidimensional clinical genomics study of children and adolescent young adults with relapsed and refractory cancers who were enrolled on other therapeutic trials to determine the feasibility of a genome guided precision therapy protocol in these patients.
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- 09-07-23 09-07-23 - Simon Heim
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dbGAP
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9 juli 2023
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Creative Commons BY 4.0
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dbGaP phs001052 Multi-Dimensional ClinOmics for Precision Therapy
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID and consent group of participants with relapsed and refractory cancer and involved in the "Modelling Multi-Dimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A report from the Center for Cancer Research" project.
- Subject ID, sample ID, and sample use variable obtained from participants with relapsed and refractory cancer and involved in the "Modelling Multi-Dimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A report from the Center for Cancer Research" project.
- Subject ID, age onset, and sex of participants with relapsed and refractory cancer and involved in the "Modelling Multi-Dimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A report from the Center for Cancer Research" project.
- Sample ID, body site where sample was collected, analyte type, tumor status, primary metastatic tumor, name of the center which conducted sequencing of participants with relapsed and refractory cancer and involved in the "Modelling Multi-Dimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A report from the Center for Cancer Research" project.
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Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID and consent group of participants with relapsed and refractory cancer and involved in the "Modelling Multi-Dimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A report from the Center for Cancer Research" project.
- Subject ID, sample ID, and sample use variable obtained from participants with relapsed and refractory cancer and involved in the "Modelling Multi-Dimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A report from the Center for Cancer Research" project.
- Subject ID, age onset, and sex of participants with relapsed and refractory cancer and involved in the "Modelling Multi-Dimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A report from the Center for Cancer Research" project.
- Sample ID, body site where sample was collected, analyte type, tumor status, primary metastatic tumor, name of the center which conducted sequencing of participants with relapsed and refractory cancer and involved in the "Modelling Multi-Dimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A report from the Center for Cancer Research" project.
Name
Type
Description | Question | Decode (Coded Value)
Datatype
Alias
Item Group
Inclusion and exclusion criteria
C1512693 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
C0680251 (UMLS CUI [1,2])
The study was comprised of a unique cohort of 59 pediatric patients with solid tumors outside of the central nervous system (CNS) who presented to the National Institutes of Health (NIH) from 2010 to December 2014. Patients had to have matched tumor/normal DNA and RNA available for analysis to qualify for the study.
Item
The study was comprised of a unique cohort of 59 pediatric patients with solid tumors outside of the central nervous system (CNS) who presented to the National Institutes of Health (NIH) from 2010 to December 2014. Patients had to have matched tumor/normal DNA and RNA available for analysis to qualify for the study.
boolean
C1709709 (UMLS CUI [1,1])
C1521725 (UMLS CUI [1,2])
C0280100 (UMLS CUI [1,3])
C0205101 (UMLS CUI [1,4])
C3714787 (UMLS CUI [1,5])
C0027468 (UMLS CUI [1,6])
C0332168 (UMLS CUI [1,7])
C0150103 (UMLS CUI [1,8])
C4331441 (UMLS CUI [1,9])
C4331443 (UMLS CUI [1,10])
C0035668 (UMLS CUI [1,11])
C0012854 (UMLS CUI [1,12])
C0871309 (UMLS CUI [1,13])
C0936012 (UMLS CUI [1,14])
C1521725 (UMLS CUI [1,2])
C0280100 (UMLS CUI [1,3])
C0205101 (UMLS CUI [1,4])
C3714787 (UMLS CUI [1,5])
C0027468 (UMLS CUI [1,6])
C0332168 (UMLS CUI [1,7])
C0150103 (UMLS CUI [1,8])
C4331441 (UMLS CUI [1,9])
C4331443 (UMLS CUI [1,10])
C0035668 (UMLS CUI [1,11])
C0012854 (UMLS CUI [1,12])
C0871309 (UMLS CUI [1,13])
C0936012 (UMLS CUI [1,14])