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ID

45805

Beskrivning

Principal Investigator: Patrick Ellinor, MD, PhD, Massachusetts General Hospital, Boston, MA, USA MeSH: Atrial Fibrillation https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001062 The Massachusetts General Hospital (MGH) Atrial Fibrillation Study was initiated in 2001. The study has enrolled serial probands, unaffected and affected family members with atrial fibrillation. At enrollment participants undergo a structured interview to systematically capture their past medical history, AF treatments, and family history. An electrocardiogram is performed; the results of an echocardiogram are obtained; and blood samples are obtained. For the TOPMed WGS project only early-onset atrial fibrillation cases were sequenced. Early-onset atrial fibrillation was defined as an age of onset prior to 66 years of age. Comprehensive phenotypic and pedigree data for study participants are available through dbGaP phs001001.

Länk

dbGaP-study=phs001062

Nyckelord

  1. 2023-06-23 2023-06-23 - Chiara Middel
Rättsinnehavare

Patrick Ellinor, MD, PhD, Massachusetts General Hospital, Boston, MA, USA

Uppladdad den

23 juni 2023

DOI

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Licens

Creative Commons BY 4.0

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    dbGaP phs001062 NHLBI TOPMed - NHGRI CCDG: Massachusetts General Hospital (MGH) Atrial Fibrillation Study

    Eligibility Criteria

    Inclusion and exclusion criteria
    Beskrivning

    Inclusion and exclusion criteria

    Alias
    UMLS CUI [1,1]
    C1512693
    UMLS CUI [1,2]
    C0680251
    Probands were included if they had an onset of atrial fibrillation prior to age 66 years and they did not have a history of a myocardial infarction, heart failure or overt structural heart disease as assessed by echocardiography.
    Beskrivning

    Elig.phs001062.v5.p2.1

    Datatyp

    boolean

    Alias
    UMLS CUI [1,1]
    C1512693
    UMLS CUI [1,2]
    C1279919
    UMLS CUI [1,3]
    C0206132
    UMLS CUI [1,4]
    C0004238
    UMLS CUI [1,5]
    C1298908
    UMLS CUI [1,6]
    C0262926
    UMLS CUI [1,7]
    C0027051
    UMLS CUI [1,8]
    C0018801
    UMLS CUI [1,9]
    C1290384
    UMLS CUI [1,10]
    C1516048
    UMLS CUI [1,11]
    C0013516

    Similar models

    Eligibility Criteria

    Name
    Typ
    Description | Question | Decode (Coded Value)
    Datatyp
    Alias
    Item Group
    Inclusion and exclusion criteria
    C1512693 (UMLS CUI [1,1])
    C0680251 (UMLS CUI [1,2])
    Elig.phs001062.v5.p2.1
    Item
    Probands were included if they had an onset of atrial fibrillation prior to age 66 years and they did not have a history of a myocardial infarction, heart failure or overt structural heart disease as assessed by echocardiography.
    boolean
    C1512693 (UMLS CUI [1,1])
    C1279919 (UMLS CUI [1,2])
    C0206132 (UMLS CUI [1,3])
    C0004238 (UMLS CUI [1,4])
    C1298908 (UMLS CUI [1,5])
    C0262926 (UMLS CUI [1,6])
    C0027051 (UMLS CUI [1,7])
    C0018801 (UMLS CUI [1,8])
    C1290384 (UMLS CUI [1,9])
    C1516048 (UMLS CUI [1,10])
    C0013516 (UMLS CUI [1,11])

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