ID

45764

Description

Principal Investigator: Chanock SJ, MD, National Cancer Institute, Bethesda, MD, USA MeSH: Thyroid Cancer, Papillary,Chernobyl Nuclear Accident,Neoplasms, Radiation-Induced,Iodine Radioisotopes https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001134 The April 26, 1986 accident at the Chernobyl nuclear power plant in northern Ukraine resulted in the release of radioactive contaminants, which were deposited in the surrounding areas in Ukraine, Belarus, and Russia. The main radiation-related health effect resulting from these exposures is the increased occurrence of thyroid cancer among individuals who were children at the time of the accident or born shortly thereafter. The purpose of this study was to conduct a comprehensive genomic landscape analysis of papillary thyroid tumors arising in individuals who were exposed as children to radioactive iodine (I-131) from the Chernobyl nuclear power plant accident.

Link

dbGaP-study=phs001134

Keywords

  1. 6/16/23 6/16/23 - Chiara Middel
Copyright Holder

Chanock SJ, MD, National Cancer Institute, Bethesda, MD, USA

Uploaded on

June 16, 2023

DOI

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License

Creative Commons BY 4.0

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dbGaP phs001134 Radiation-related Genomic Profile of Papillary Thyroid Cancer after the Chernobyl Accident

Subject ID, sex, affection status, age, radiation dose, and diagnosis of participants with papillary thyroid cancer and involved in the "Radiation-related Genomic Profile of Papillary Thyroid Cancer after the Chernobyl Accident" project.

pht011227
Description

pht011227

Alias
UMLS CUI [1,1]
C3846158
De-identified Subject ID
Description

SUBJECT_ID

Data type

string

Alias
UMLS CUI [1,1]
C4684638
UMLS CUI [1,2]
C2348585
Exposure status of the subject
Description

AFFECTION_STATUS

Data type

string

Alias
UMLS CUI [1,1]
C0449438
UMLS CUI [1,2]
C0332157
Sex of participant
Description

SEX

Data type

string

Alias
UMLS CUI [1,1]
C0079399
Age at surgery (for the thyroid cancer removal)
Description

AGE_SURG

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C0001779
UMLS CUI [1,2]
C0011008
UMLS CUI [1,3]
C0543467
Years
Age at exposure
Description

AGE_EXP

Data type

text

Measurement units
  • Years
Alias
UMLS CUI [1,1]
C0001779
UMLS CUI [1,2]
C0011008
UMLS CUI [1,3]
C0332157
Years
Radiation dose
Description

DOSE

Data type

text

Measurement units
  • mGy(milligray)
Alias
UMLS CUI [1,1]
C4019308
mGy(milligray)
Diagnosis of papillary thyroid cancer (PTC)
Description

DIAGNOSIS

Data type

string

Alias
UMLS CUI [1,1]
C0011900
UMLS CUI [1,2]
C0238463

Similar models

Subject ID, sex, affection status, age, radiation dose, and diagnosis of participants with papillary thyroid cancer and involved in the "Radiation-related Genomic Profile of Papillary Thyroid Cancer after the Chernobyl Accident" project.

Name
Type
Description | Question | Decode (Coded Value)
Data type
Alias
Item Group
pht011227
C3846158 (UMLS CUI [1,1])
SUBJECT_ID
Item
De-identified Subject ID
string
C4684638 (UMLS CUI [1,1])
C2348585 (UMLS CUI [1,2])
AFFECTION_STATUS
Item
Exposure status of the subject
string
C0449438 (UMLS CUI [1,1])
C0332157 (UMLS CUI [1,2])
SEX
Item
Sex of participant
string
C0079399 (UMLS CUI [1,1])
AGE_SURG
Item
Age at surgery (for the thyroid cancer removal)
text
C0001779 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
C0543467 (UMLS CUI [1,3])
AGE_EXP
Item
Age at exposure
text
C0001779 (UMLS CUI [1,1])
C0011008 (UMLS CUI [1,2])
C0332157 (UMLS CUI [1,3])
DOSE
Item
Radiation dose
text
C4019308 (UMLS CUI [1,1])
DIAGNOSIS
Item
Diagnosis of papillary thyroid cancer (PTC)
string
C0011900 (UMLS CUI [1,1])
C0238463 (UMLS CUI [1,2])

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