ID

45756

Description

Principal Investigator: Daphne W. Bell, PhD, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA MeSH: Endometrial Neoplasms,Carcinoma, Endometrioid https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001153 The purpose of this study was to identify somatic (tumor-specific) mutations in advanced stage endometrioid endometrial carcinoma tumor exomes. The dataset was generated at the NIH Intramural Sequencing Center (NISC) and NHGRI by next generation sequencing the exomes of 19 de-identified primary tumor DNAs, from advanced stage tumors, and matched non-tumor DNAs.

Lien

dbGaP-study=phs001153

Mots-clés

  1. 05.06.23 05.06.23 - Chiara Middel
Détendeur de droits

Daphne W. Bell, PhD, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA

Téléchargé le

5. Juni 2023

DOI

Pour une demande vous connecter.

Licence

Creative Commons BY 4.0

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dbGaP phs001153 Somatic Mutational Analysis by Exome Sequencing Late-Stage Endometrioid Endometrial Carcinoma

Eligibility Criteria

Inclusion and exclusion criteria
Description

Inclusion and exclusion criteria

Alias
UMLS CUI [1,1]
C1512693
UMLS CUI [1,2]
C0680251
Inclusion criteria:
Description

Elig.phs001153.v1.p1.1

Type de données

boolean

Alias
UMLS CUI [1,1]
C1512693
Endometrioid endometrial carcinoma
Description

Elig.phs001153.v1.p1.2

Type de données

boolean

Alias
UMLS CUI [1,1]
C0206687
UMLS CUI [1,2]
C0476089
Advanced stage tumors defined as stage III/IV (FIGO or AJCC systems)
Description

Elig.phs001153.v1.p1.3

Type de données

boolean

Alias
UMLS CUI [1,1]
C0205179
UMLS CUI [1,2]
C1300072
UMLS CUI [1,3]
C0441771
UMLS CUI [1,4]
C0441772
UMLS CUI [1,5]
C0474956
Region of tumor tissue used for DNA extraction estimated to be at least 70% neoplastic cellularity
Description

Elig.phs001153.v1.p1.4

Type de données

boolean

Alias
UMLS CUI [1,1]
C0475358
UMLS CUI [1,2]
C3839098
UMLS CUI [1,3]
C0597032
Primary tumor tissue and matched non-tumor tissue available
Description

Elig.phs001153.v1.p1.5

Type de données

boolean

Alias
UMLS CUI [1,1]
C0470187
UMLS CUI [1,2]
C0475358
UMLS CUI [1,3]
C0150103
UMLS CUI [1,4]
C0205307
UMLS CUI [1,5]
C0040300

Similar models

Eligibility Criteria

Name
Type
Description | Question | Decode (Coded Value)
Type de données
Alias
Item Group
Inclusion and exclusion criteria
C1512693 (UMLS CUI [1,1])
C0680251 (UMLS CUI [1,2])
Elig.phs001153.v1.p1.1
Item
Inclusion criteria:
boolean
C1512693 (UMLS CUI [1,1])
Elig.phs001153.v1.p1.2
Item
Endometrioid endometrial carcinoma
boolean
C0206687 (UMLS CUI [1,1])
C0476089 (UMLS CUI [1,2])
Elig.phs001153.v1.p1.3
Item
Advanced stage tumors defined as stage III/IV (FIGO or AJCC systems)
boolean
C0205179 (UMLS CUI [1,1])
C1300072 (UMLS CUI [1,2])
C0441771 (UMLS CUI [1,3])
C0441772 (UMLS CUI [1,4])
C0474956 (UMLS CUI [1,5])
Elig.phs001153.v1.p1.4
Item
Region of tumor tissue used for DNA extraction estimated to be at least 70% neoplastic cellularity
boolean
C0475358 (UMLS CUI [1,1])
C3839098 (UMLS CUI [1,2])
C0597032 (UMLS CUI [1,3])
Elig.phs001153.v1.p1.5
Item
Primary tumor tissue and matched non-tumor tissue available
boolean
C0470187 (UMLS CUI [1,1])
C0475358 (UMLS CUI [1,2])
C0150103 (UMLS CUI [1,3])
C0205307 (UMLS CUI [1,4])
C0040300 (UMLS CUI [1,5])

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