ID
45747
Descrição
Principal Investigator: Sanjay Shete, PhD, UT MD Anderson Cancer Center, Houston, TX, USA MeSH: Carcinoma, squamous cell of head and neck https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001173 Head and neck cancers have well-documented associations with tobacco and alcohol exposure, but the disease develops in only a small fraction of users, which implies an important role for genetic susceptibility. Therefore, head and neck cancers are an excellent model for studying genetic susceptibility to environmental carcinogens. The primary goal of this study is to perform a comprehensive two-stage, high-density, genome-wide single-nucleotide polymorphism (SNP) analysis of head and neck cancer cases and corresponding frequency matched controls to identify novel genetic risk factors for head and neck cancer. In the study, we genotyped 2242 head and neck cancer cases and 1198 controls using Illumina HumanOmniExpress-12v1 BeadChip.
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Versões (1)
- 04/06/2023 04/06/2023 - Chiara Middel
Titular dos direitos
Sanjay Shete, PhD, UT MD Anderson Cancer Center, Houston, TX, USA
Transferido a
4 de junho de 2023
DOI
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Licença
Creative Commons BY 4.0
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dbGaP phs001173 Head and Neck Cancer Genome-wide Association Study
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID, consent group, and affection status of participants with or without head and neck cancer and involved in the "Head and Neck Cancer Genome-wide Association Study" project.
- Subject ID, sample ID, sample source, source sample ID, and sample use variable of participants with or without head and neck cancer and involved in the "Head and Neck Cancer Genome-wide Association Study" project.
- Subject ID, case or control, age, sex, race, and duplicated samples of participants with or without head and neck cancer and involved in the "Head and Neck Cancer Genome-wide Association Study" project.
- Sample ID, case or control, body site where sample was collected, analyte type, tumor status, cell or tissue type or subtype of sample, and name of genotyping center of Subject ID, case or control, age, sex, race, and duplicated samples of participants with or without head and neck cancer and involved in the "Head and Neck Cancer Genome-wide Association Study" project.
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Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- Subject ID, consent group, and affection status of participants with or without head and neck cancer and involved in the "Head and Neck Cancer Genome-wide Association Study" project.
- Subject ID, sample ID, sample source, source sample ID, and sample use variable of participants with or without head and neck cancer and involved in the "Head and Neck Cancer Genome-wide Association Study" project.
- Subject ID, case or control, age, sex, race, and duplicated samples of participants with or without head and neck cancer and involved in the "Head and Neck Cancer Genome-wide Association Study" project.
- Sample ID, case or control, body site where sample was collected, analyte type, tumor status, cell or tissue type or subtype of sample, and name of genotyping center of Subject ID, case or control, age, sex, race, and duplicated samples of participants with or without head and neck cancer and involved in the "Head and Neck Cancer Genome-wide Association Study" project.
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