ID

45681

Descripción

Principal Investigator: Nathan O. Stitziel, MD, PhD, McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA MeSH: Coronary Artery Disease https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001227 The genetic basis of coronary artery disease in individuals of non-European ancestry is largely unknown. The Washington University Coronary Artery Disease Study (WUCADS) recruited participants of non-European ancestry with and without coronary artery disease to address this question. Whole genome sequencing in WUCADS was performed at the McDonnell Genome Institute at Washington University.

Link

dbGaP study = phs001227

Palabras clave

Versiones (1)
  1. 26/4/23 26/4/23 - Simon Heim
Titular de derechos de autor

Nathan O. Stitziel, MD, PhD, McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA

Subido en

26 de abril de 2023

DOI

Para solicitar uno, por favor iniciar sesión.

Licencia

Creative Commons BY 4.0
Comentarios del modelo :

Puede comentar sobre el modelo de datos aquí. A través de las burbujas de diálogo en los grupos de elementos y elementos, puede agregar comentarios específicos.

Volver a los comentarios del modelo
Comentarios de grupo de elementos para :

Comentarios del elemento para :

  • El más nuevo
  • Más antiguo
  • Popular
  • El más nuevo
    • El más nuevo
    • Más antiguo
    • Popular

    Sin comentarios

    Para descargar modelos de datos, debe haber iniciado sesión. Por favor iniciar sesión o Registrate gratis.

    dbGaP phs001227 Washington University Coronary Artery Disease Study

    Inglés

    Eligibility Criteria

    5 formularios  
    Inclusion and exclusion criteria
    Descripción

    Inclusion and exclusion criteria

    Alias
    UMLS CUI [1,1]
    C1512693
    UMLS CUI [1,2]
    C0680251
    *Inclusion/Exclusion criteria:* We recruited WUCADS participants from the BJC HealthCare network. Subjects were eligible to participate as a case if they were of self-identified non-European ancestry and had a history of significant coronary artery disease defined as myocardial infarction, coronary revascularization, or stenosis ≥ 50% in a major epicardial coronary artery. To enrich cases for those most likely to be influenced by genetic factors, we preferentially focused on individuals who were diagnosed with significant coronary artery disease at or before the age of 60 and 70 for men and women, respectively. Subjects were eligible to participate as a control if they were of self-identified non-European ancestry and did not have a history of significant coronary artery disease defined above.
    Descripción

    *Inclusion/Exclusion criteria:* We recruited WUCADS participants from the BJC HealthCare network. Subjects were eligible to participate as a case if they were of self-identified non-European ancestry and had a history of significant coronary artery disease defined as myocardial infarction, coronary revascularization, or stenosis ≥ 50% in a major epicardial coronary artery. To enrich cases for those most likely to be influenced by genetic factors, we preferentially focused on individuals who were diagnosed with significant coronary artery disease at or before the age of 60 and 70 for men and women, respectively. Subjects were eligible to participate as a control if they were of self-identified non-European ancestry and did not have a history of significant coronary artery disease defined above.

    Tipo de datos

    boolean

    Alias
    UMLS CUI [1,1]
    C2827031
    UMLS CUI [1,2]
    C2985691
    UMLS CUI [2,1]
    C0085973
    UMLS CUI [2,2]
    C5447420
    UMLS CUI [2,3]
    C1518422
    UMLS CUI [2,4]
    C0239307
    UMLS CUI [2,5]
    C0262926
    UMLS CUI [2,6]
    C1956346
    UMLS CUI [2,7]
    C0027051
    UMLS CUI [2,8]
    C0877341
    UMLS CUI [2,9]
    C0242231
    UMLS CUI [3,1]
    C0085973
    UMLS CUI [3,2]
    C0750501
    UMLS CUI [3,3]
    C1658408
    UMLS CUI [3,4]
    C0206132
    UMLS CUI [4,1]
    C4553389
    UMLS CUI [4,2]
    C1518422
    UMLS CUI [4,3]
    C0239307
    Volver a la parte superior de la página

    Similar models

    Eligibility Criteria

    5 formularios
    Name
    Tipo
    Description | Question | Decode (Coded Value)
    Tipo de datos
    Alias
    Item Group
    Inclusion and exclusion criteria
    C1512693 (UMLS CUI [1,1])
    C0680251 (UMLS CUI [1,2])
    *Inclusion/Exclusion criteria:* We recruited WUCADS participants from the BJC HealthCare network. Subjects were eligible to participate as a case if they were of self-identified non-European ancestry and had a history of significant coronary artery disease defined as myocardial infarction, coronary revascularization, or stenosis ≥ 50% in a major epicardial coronary artery. To enrich cases for those most likely to be influenced by genetic factors, we preferentially focused on individuals who were diagnosed with significant coronary artery disease at or before the age of 60 and 70 for men and women, respectively. Subjects were eligible to participate as a control if they were of self-identified non-European ancestry and did not have a history of significant coronary artery disease defined above.
    Item
    *Inclusion/Exclusion criteria:* We recruited WUCADS participants from the BJC HealthCare network. Subjects were eligible to participate as a case if they were of self-identified non-European ancestry and had a history of significant coronary artery disease defined as myocardial infarction, coronary revascularization, or stenosis ≥ 50% in a major epicardial coronary artery. To enrich cases for those most likely to be influenced by genetic factors, we preferentially focused on individuals who were diagnosed with significant coronary artery disease at or before the age of 60 and 70 for men and women, respectively. Subjects were eligible to participate as a control if they were of self-identified non-European ancestry and did not have a history of significant coronary artery disease defined above.
    boolean
    C2827031 (UMLS CUI [1,1])
    C2985691 (UMLS CUI [1,2])
    C0085973 (UMLS CUI [2,1])
    C5447420 (UMLS CUI [2,2])
    C1518422 (UMLS CUI [2,3])
    C0239307 (UMLS CUI [2,4])
    C0262926 (UMLS CUI [2,5])
    C1956346 (UMLS CUI [2,6])
    C0027051 (UMLS CUI [2,7])
    C0877341 (UMLS CUI [2,8])
    C0242231 (UMLS CUI [2,9])
    C0085973 (UMLS CUI [3,1])
    C0750501 (UMLS CUI [3,2])
    C1658408 (UMLS CUI [3,3])
    C0206132 (UMLS CUI [3,4])
    C4553389 (UMLS CUI [4,1])
    C1518422 (UMLS CUI [4,2])
    C0239307 (UMLS CUI [4,3])
    Volver a la parte superior de la página 

    Ayuda

    Do you need help on how to use the search function? Please watch the corresponding tutorial video for more details and learn how to use the search function most efficiently.

    Watch Tutorial