ID

45652

Beschrijving

Principal Investigator: Richard A. Young, Whitehead Institute for Biomedical Research, Cambridge, MA and Massachusetts Institute of Technology, Cambridge, MA, USA MeSH: Precursor T-Cell Lymphoblastic Leukemia-Lymphoma https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001242 ChIP-Seq data from 102 cell lines were processed to identify insertions relative to the human reference genome. To confirm the ability of a computational pipeline to identify insertions that are actually present in these genomes, we PCR-amplified and deeply sequenced regions where insertions were predicted to exist in MOLT4 T-cell acute lymphoblastic leukemia cells. The current study release makes available sequences of amplicons from a tumor cell genome (MOLT4) where a computational pipeline predicted small insertions from orthogonal data.

Link

dbGaP study = phs001242

Trefwoorden

  1. 21-03-23 21-03-23 - Simon Heim
Houder van rechten

Richard A. Young, Whitehead Institute for Biomedical Research, Cambridge, MA and Massachusetts Institute of Technology, Cambridge, MA, USA

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21 maart 2023

DOI

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Licentie

Creative Commons BY 4.0

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dbGaP phs001242 Small genomic insertions form enhancers that misregulate oncogenes

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pht006071
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pht006071

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UMLS CUI [1,1]
C3846158
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text

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UMLS CUI [1,1]
C1299222
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text

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C0021430
UMLS CUI [1,2]
C0449438

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Type
Description | Question | Decode (Coded Value)
Datatype
Alias
Item Group
pht006071
C3846158 (UMLS CUI [1,1])
SUBJECT_ID
Item
Sample ID
text
C1299222 (UMLS CUI [1,1])
Item
Consent status
text
C0021430 (UMLS CUI [1,1])
C0449438 (UMLS CUI [1,2])
Code List
Consent status
CL Item
General Research Use (GRU) (1)
C0021430 (UMLS CUI [1,1])
C0242481 (UMLS CUI [1,2])

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