ID
45642
Descrizione
Principal Investigator: Roberta L. Hannibal, Stanford University School of Medicine, Stanford, CA, USA MeSH: Pre-eclampsia,Hypertension, Pregnancy-Induced,Diabetes, Gestational,Premature Birth,Anemia,Trisomy,Abnormalities https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001320 Chorionic villus sampling (CVS) is routinely used for prenatal diagnosis of cytogenetic disorders, but also possesses great potential for studying placentation. To better understand villi biology, human placentation, and how these relate to pregnancy outcomes, we examined the morphology and transcriptomes of villi obtained via CVS from 10-14 weeks of pregnancy and correlated these with pregnancy attributes and clinical outcomes.
collegamento
Keywords
versioni (1)
- 13/03/23 13/03/23 - Simon Heim
Titolare del copyright
Roberta L. Hannibal, Stanford University School of Medicine, Stanford, CA, USA
Caricato su
13 marzo 2023
DOI
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Licenza
Creative Commons BY 4.0
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dbGaP phs001320 Investigating Human Placentation and Pregnancy Using First Trimester Chorionic Villi
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- This subject consent file includes subject IDs and consent group information. A SUBJECT_ID is labeled as a "chorionic villus sample from a single human placenta."
- This subject sample mapping file contains a mapping of study subject IDs to sample IDs. Samples are the final preps submitted for genotyping, sequencing, and/or expression data. For example, if one patient (subject ID) gave one sample, and that sample was processed differently to generate 2 sequencing runs, there would be two rows, both using the same subject ID, but having 2 unique sample IDs. The data table also includes sample use.
- This subject phenotype data table includes subject's mother's ethnicity. A SUBJECT_ID is labeled as a "chorionic villus sample from a single human placenta."
- This sample attributes data table includes body site where sample was collected, histological type, tumor status, sample's sex, analyte type, RIN, and chorionic villi sample (CVS) scores (n=4 variables; budding, vein, branching and composite).
Similar models
Eligibility Criteria
- StudyEvent: SEV1
- Eligibility Criteria
- This subject consent file includes subject IDs and consent group information. A SUBJECT_ID is labeled as a "chorionic villus sample from a single human placenta."
- This subject sample mapping file contains a mapping of study subject IDs to sample IDs. Samples are the final preps submitted for genotyping, sequencing, and/or expression data. For example, if one patient (subject ID) gave one sample, and that sample was processed differently to generate 2 sequencing runs, there would be two rows, both using the same subject ID, but having 2 unique sample IDs. The data table also includes sample use.
- This subject phenotype data table includes subject's mother's ethnicity. A SUBJECT_ID is labeled as a "chorionic villus sample from a single human placenta."
- This sample attributes data table includes body site where sample was collected, histological type, tumor status, sample's sex, analyte type, RIN, and chorionic villi sample (CVS) scores (n=4 variables; budding, vein, branching and composite).
C0680251 (UMLS CUI [1,2])
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C0020017 (UMLS CUI [1,6])
C0742765 (UMLS CUI [1,2])
C0043210 (UMLS CUI [1,3])
C0008509 (UMLS CUI [1,4])
C4700202 (UMLS CUI [1,5])
C0332437 (UMLS CUI [1,6])
C2708733 (UMLS CUI [1,7])