ID

45626

Beskrivning

Principal Investigator: S. Louis Bridges, Jr., MD, PhD, University of Alabama at Birmingham, Birmingham, AL, USA MeSH: Arthritis, Rheumatoid https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001360 The Consortium for the Longitudinal Evaluation of African-Americans with Early Rheumatoid Arthritis (*CLEAR*) Registry and Repository, supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (*NIAMS*), was established in 2000 to provide a resource for the scientific community to explore genetic and non-genetic factors affecting rheumatoid arthritis (*RA*) occurrence and outcomes in African Americans. The long term objective is a database and a repository of 1,100 RA and 550 matched healthy African-American subjects. This CLEAR Registry and Repository has two arms: a longitudinal arm for subjects with early RA (enrollment from 2000 to 2005) and a cross-sectional arm for subjects with any disease duration (enrollment from 2006 to 2012). CLEAR has two components: a database and a repository. The database contains extensive demographic, socioeconomic, clinical and radiographic (radiographs of hands and feet) information and bone mineral density data from DEXA scans. The repository contains genomic DNA, plasma and serum on most of the participants. Participants in CLEAR II had RNA isolated from peripheral blood cells.

Länk

dbGaP study = phs001360

Nyckelord

  1. 2023-02-28 2023-02-28 - Simon Heim
Rättsinnehavare

S. Louis Bridges, Jr., MD, PhD, University of Alabama at Birmingham, Birmingham, AL, USA

Uppladdad den

28 februari 2023

DOI

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Licens

Creative Commons BY 4.0

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dbGaP phs001360 Genome-Wide Association Study in African-Americans with RA

This subject phenotype table contains subject IDs, sex, Rheumatoid Arthritis (RA) onset age, age at baseline, disease duration, height, weight, cyclic citrullinated peptide (CCP) and rheumatoid factor (RF) IgM status, smoking tobacco and drinking alcohol status, medication and steroid use history, and RA status.

pht006295
Beskrivning

pht006295

Alias
UMLS CUI [1,1]
C3846158
De-identified Subject ID
Beskrivning

SUBJECT_ID

Datatyp

string

Alias
UMLS CUI [1,1]
C4684638
UMLS CUI [1,2]
C2348585
Participant Gender
Beskrivning

Sex

Datatyp

text

Alias
UMLS CUI [1,1]
C0079399
Rheumatoid Arthritis (RA) onset age
Beskrivning

AgeRA

Datatyp

float

Måttenheter
  • years
Alias
UMLS CUI [1,1]
C0003873
UMLS CUI [1,2]
C0206132
years
Age at baseline
Beskrivning

AgeScreen

Datatyp

float

Måttenheter
  • years
Alias
UMLS CUI [1,1]
C0001779
UMLS CUI [1,2]
C1442488
years
Disease duration at baseline visit
Beskrivning

DisDurMonths

Datatyp

float

Måttenheter
  • months
Alias
UMLS CUI [1,1]
C1442488
UMLS CUI [1,2]
C0545082
UMLS CUI [1,3]
C0872146
months
Height measured at enrollment
Beskrivning

Height

Datatyp

float

Måttenheter
  • inches
Alias
UMLS CUI [1,1]
C0005890
UMLS CUI [1,2]
C1442488
inches
Subject's weight
Beskrivning

Weight

Datatyp

float

Måttenheter
  • pounds
Alias
UMLS CUI [1,1]
C0005910
pounds
CCP positivity
Beskrivning

CCP_status

Datatyp

text

Alias
UMLS CUI [1,1]
C5676688
RF positivity
Beskrivning

RFIgM_status

Datatyp

text

Alias
UMLS CUI [1,1]
C0035448
Smoke tobacco or other substance
Beskrivning

SmokingStatus

Datatyp

text

Alias
UMLS CUI [1,1]
C0543414
UMLS CUI [1,2]
C0848734
Drink alcohol
Beskrivning

Alcohol

Datatyp

text

Alias
UMLS CUI [1,1]
C0001948
Medication use history
Beskrivning

MedUse

Datatyp

text

Alias
UMLS CUI [1,1]
C0262926
UMLS CUI [1,2]
C0013227
Steroid use history
Beskrivning

SteroidBL

Datatyp

text

Alias
UMLS CUI [1,1]
C0281991
UMLS CUI [1,2]
C0262926
RA or not RA
Beskrivning

Status

Datatyp

text

Alias
UMLS CUI [1,1]
C0003873

Similar models

This subject phenotype table contains subject IDs, sex, Rheumatoid Arthritis (RA) onset age, age at baseline, disease duration, height, weight, cyclic citrullinated peptide (CCP) and rheumatoid factor (RF) IgM status, smoking tobacco and drinking alcohol status, medication and steroid use history, and RA status.

Name
Typ
Description | Question | Decode (Coded Value)
Datatyp
Alias
Item Group
pht006295
C3846158 (UMLS CUI [1,1])
SUBJECT_ID
Item
De-identified Subject ID
string
C4684638 (UMLS CUI [1,1])
C2348585 (UMLS CUI [1,2])
Item
Participant Gender
text
C0079399 (UMLS CUI [1,1])
Code List
Participant Gender
CL Item
Male (1)
C0086582 (UMLS CUI [1,1])
CL Item
Female (2)
C0086287 (UMLS CUI [1,1])
AgeRA
Item
Rheumatoid Arthritis (RA) onset age
float
C0003873 (UMLS CUI [1,1])
C0206132 (UMLS CUI [1,2])
AgeScreen
Item
Age at baseline
float
C0001779 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
DisDurMonths
Item
Disease duration at baseline visit
float
C1442488 (UMLS CUI [1,1])
C0545082 (UMLS CUI [1,2])
C0872146 (UMLS CUI [1,3])
Height
Item
Height measured at enrollment
float
C0005890 (UMLS CUI [1,1])
C1442488 (UMLS CUI [1,2])
Weight
Item
Subject's weight
float
C0005910 (UMLS CUI [1,1])
Item
CCP positivity
text
C5676688 (UMLS CUI [1,1])
Code List
CCP positivity
CL Item
negative (NEG)
CL Item
positive (POS)
CL Item
unknown (UNK)
Item
RF positivity
text
C0035448 (UMLS CUI [1,1])
Code List
RF positivity
CL Item
negative (NEG)
CL Item
positive (POS)
CL Item
unknown (UNK)
SmokingStatus
Item
Smoke tobacco or other substance
text
C0543414 (UMLS CUI [1,1])
C0848734 (UMLS CUI [1,2])
Alcohol
Item
Drink alcohol
text
C0001948 (UMLS CUI [1,1])
MedUse
Item
Medication use history
text
C0262926 (UMLS CUI [1,1])
C0013227 (UMLS CUI [1,2])
SteroidBL
Item
Steroid use history
text
C0281991 (UMLS CUI [1,1])
C0262926 (UMLS CUI [1,2])
Item
RA or not RA
text
C0003873 (UMLS CUI [1,1])
Code List
RA or not RA
CL Item
Control (1)
C3274648 (UMLS CUI [1,1])
CL Item
Case (2)
C3274647 (UMLS CUI [1,1])

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