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ID

45595

Beschrijving

Principal Investigator: Louis Fiore, MD, VA Boston Healthcare System, Boston, MA, USA MeSH: Neoplasms https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs001374 The Research for Precision Oncology Program (RePOP) is a research activity that establishes a cohort of Veterans diagnosed with cancer and who have had genomic analyses performed on their tumor tissue as part of standard of care. All data relevant to a patient's cancer and cancer care will be collected under RePOP, including patient demographics, co-morbidities, genomic analysis, treatments, medications, lab values, imaging studies, and outcomes. All RePOP participants will have signed/verbal informed consent and signed HIPAA authorization to have their data stored and shared from RePOP's Precision Oncology Program Data Repository (PODR). The Applied Proteogenomics OrganizationaL Learning and Outcomes (APOLLO) network is a collaboration between NCI, the Department of Defense (DoD), and the Department of Veterans Affairs (VA) to incorporate proteogenomics into patient care as a way of looking beyond the genome, to the activity and expression of the proteins that the genome encodes. The emerging field of proteogenomics aims to better predict how patients will respond to therapy by screening their tumors for both genetic abnormalities and protein information, an approach that has been made possible in recent years due to advances in proteomic technology.

Link

dbGaP study = phs001374

Trefwoorden

  1. 07-02-23 07-02-23 - Simon Heim
Houder van rechten

Louis Fiore, MD, VA Boston Healthcare System, Boston, MA, USA

Geüploaded op

7 februari 2023

DOI

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Licentie

Creative Commons BY 4.0

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    dbGaP phs001374 VA APOLLO Project - Research for Precision Oncology (RePOP)

    Eligibility Criteria

    Inclusion and exclusion criteria
    Beschrijving

    Inclusion and exclusion criteria

    Alias
    UMLS CUI [1,1]
    C1512693
    UMLS CUI [1,2]
    C0680251
    To be eligible to participate in the Research for the Precision Oncology Program, an individual must: Be a VA patient with a cancer diagnosis as confirmed by pathology, physician report, medical record, etc.
    Beschrijving

    To be eligible to participate in the Research for the Precision Oncology Program, an individual must: Be a VA patient with a cancer diagnosis as confirmed by pathology, physician report, medical record, etc.

    Datatype

    boolean

    Alias
    UMLS CUI [1,1]
    C1548635
    UMLS CUI [1,2]
    C0035168
    UMLS CUI [1,3]
    C1706245
    UMLS CUI [1,4]
    C0027651
    UMLS CUI [1,5]
    C0920688
    UMLS CUI [1,6]
    C0521093
    UMLS CUI [1,7]
    C0030664
    UMLS CUI [1,8]
    C0184603
    UMLS CUI [1,9]
    C0025102
    Have had mutational analysis performed on a cancer and/or blood specimen as part of routine clinical care
    Beschrijving

    Have had mutational analysis performed on a cancer and/or blood specimen as part of routine clinical care

    Datatype

    boolean

    Alias
    UMLS CUI [1,1]
    C0012878
    UMLS CUI [1,2]
    C0006826
    UMLS CUI [1,3]
    C0178913
    UMLS CUI [1,4]
    C0205210
    UMLS CUI [1,5]
    C0205547
    Be at least 18 years of age
    Beschrijving

    Be at least 18 years of age

    Datatype

    boolean

    Alias
    UMLS CUI [1,1]
    C0001779
    Plan to continue to seek care at the VA
    Beschrijving

    Plan to continue to seek care at the VA

    Datatype

    boolean

    Alias
    UMLS CUI [1,1]
    C0032074
    UMLS CUI [1,2]
    C0599788
    Be competent to provide informed consent
    Beschrijving

    Be competent to provide informed consent

    Datatype

    boolean

    Alias
    UMLS CUI [1,1]
    C0086035
    UMLS CUI [1,2]
    C1999230
    UMLS CUI [1,3]
    C0021430

    Similar models

    Eligibility Criteria

    Name
    Type
    Description | Question | Decode (Coded Value)
    Datatype
    Alias
    Item Group
    Inclusion and exclusion criteria
    C1512693 (UMLS CUI [1,1])
    C0680251 (UMLS CUI [1,2])
    To be eligible to participate in the Research for the Precision Oncology Program, an individual must: Be a VA patient with a cancer diagnosis as confirmed by pathology, physician report, medical record, etc.
    Item
    To be eligible to participate in the Research for the Precision Oncology Program, an individual must: Be a VA patient with a cancer diagnosis as confirmed by pathology, physician report, medical record, etc.
    boolean
    C1548635 (UMLS CUI [1,1])
    C0035168 (UMLS CUI [1,2])
    C1706245 (UMLS CUI [1,3])
    C0027651 (UMLS CUI [1,4])
    C0920688 (UMLS CUI [1,5])
    C0521093 (UMLS CUI [1,6])
    C0030664 (UMLS CUI [1,7])
    C0184603 (UMLS CUI [1,8])
    C0025102 (UMLS CUI [1,9])
    Have had mutational analysis performed on a cancer and/or blood specimen as part of routine clinical care
    Item
    Have had mutational analysis performed on a cancer and/or blood specimen as part of routine clinical care
    boolean
    C0012878 (UMLS CUI [1,1])
    C0006826 (UMLS CUI [1,2])
    C0178913 (UMLS CUI [1,3])
    C0205210 (UMLS CUI [1,4])
    C0205547 (UMLS CUI [1,5])
    Be at least 18 years of age
    Item
    Be at least 18 years of age
    boolean
    C0001779 (UMLS CUI [1,1])
    Plan to continue to seek care at the VA
    Item
    Plan to continue to seek care at the VA
    boolean
    C0032074 (UMLS CUI [1,1])
    C0599788 (UMLS CUI [1,2])
    Be competent to provide informed consent
    Item
    Be competent to provide informed consent
    boolean
    C0086035 (UMLS CUI [1,1])
    C1999230 (UMLS CUI [1,2])
    C0021430 (UMLS CUI [1,3])

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